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Berra Yazar-Klosinski [is the] chief scientific officer at the Multidisciplinary Association for Psychedelic Studies (MAPS). I ... committed to working with her on the phase 3 program that would assess the efficacy and safety of MDMA–known recreationally as Molly or Ecstasy–for severe PTSD, or post-traumatic stress disorder. Although more than half a dozen phase 2 studies have demonstrated the effectiveness and safety of MDMA for PTSD, early trials often fail to accurately predict the outcome of the larger, multisite phase 3 trials that follow. In the case of MDMA, we have been lucky. At 15 study sites across three countries, working with more than 70 different therapists and with study participants with childhood trauma, depression and a treatment-resistant subtype of PTSD, we have obtained incredibly promising results. Phase 3 study participants receiving MDMA-assisted therapy showed a greater reduction in PTSD symptoms and functional impairment than participants receiving placebo plus therapy. In addition, their symptoms of depression plummeted. By the end of the study more than 67 percent of the participants in the MDMA group no longer met criteria for PTSD. An additional 21 percent had a clinically meaningful response–in other words, a lessening of anxiety, depression, vigilant mental states, and emotional flatness. MDMA-assisted therapy did not increase measures of suicidal thinking or behavior. MDMA also did not demonstrate any measurable misuse potential.
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President Biden became the first sitting president to give extensive comments supporting the right to repair and acknowledging the anticompetitive practices of electronics manufacturers that have spent the last decade creating repair monopolies and making it difficult for consumers to fix the things they own. At a cabinet meeting Monday, Biden gave an update on the executive order he issued last year that directed the Federal Trade Commission to create right to repair rules that would enforce against anticompetitive practices. "Too many areas, if you own a product, from a smartphone to a tractor, you don't have the freedom to choose how or where to repair that item you purchased," Biden added. "It's broke. Well, what do I do about it if it's broke, you had to go to the dealer and you had to pay the dealer's cost, the dealer's price. If you tried to fix it yourself, some manufacturers actually would void the warranty." Biden was referring here to practices by John Deere and Apple, as well as by video game console manufacturers, who as Motherboard reported violate the Magnusson-Moss Warranty Act with "Warranty Void if Removed" stickers. Biden ... also took credit for recent moves from Amazon and Microsoft that will, in theory, make it easier for people to gain access to repair parts and manuals for their devices. "It's going to make it easy for millions of Americans to repair their electronics instead of paying an arm and a leg to repair or just throwing a device out."
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Three British women, one of whom has incurable cancer, have shattered the world record for rowing across the Atlantic. Kat Cordiner, who has secondary ovarian cancer, and teammates Abby Johnston and Charlotte Irving, arrived in Antigua on Sunday evening. The women completed the 3,000-mile crossing from La Gomera in the Canary Islands to English Harbour in 42 days ... knocking an astonishing seven days off the female trio record in the Talisker Whisky Atlantic Challenge. Rowing the world's second largest ocean is acknowledged as the ultimate endurance race. More people have summitted Mount Everest than have successfully rowed the Atlantic and fewer than 20% of ocean rowers are women. It is thought Ms Cordiner is the first person to tackle this challenge as a cancer patient. The women are raising money for Cancer Research UK, Macmillan Cancer Support and The Royal Marsden Cancer Charity. Race organisers said they had shown the impossible was possible. Ms Cordiner, 42, Ms Irving, 31, and Ms Johnston, 32, were on a 25ft boat – called Dolly Parton – rowing two hours on and two hours off. During their epic trip they experienced scorching heat, enormous night-time waves, sleep deprivation, blisters and callouses on their hands, and sharks trailing their small boat. Ms Cordiner said: "The doctors have told me I don't have decades, I have years, so I really want to make the most of them. I don't want to muck around doing stuff that doesn't matter – I want to do things that are challenging and fun."
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Giraffe numbers have increased across Africa, new research shows, a rare spot of good news in the conservation world. According to a recent analysis of survey data from across the African continent, the total giraffe population is now around 117,000, approximately 20 percent higher than it was thought to be in 2015, when the last major survey was published. This rise is a result of genuine growth in some areas, but also stems from more accurate census data, says Julian Fennessy, executive director of the Giraffe Conservation Foundation, based in Namibia. "It's great to see these numbers increasing," says Fennessy, a co-author of the new research. Giraffes were once considered a single species. But recent genetic evidence shows there are likely four species of giraffe, three of which have increased considerably in number: northern, reticulated, and Masai giraffes. The fourth, southern giraffes, have remained relatively stable. Data were collected during the last few years across 21 countries, by governments, researchers, nonprofits, and even citizen scientists. Fennessy and six co-authors then analyzed this vast trove of information and published the results ... in the peer-reviewed research volume Imperiled: The Encyclopedia of Conservation. Northern giraffes, the most threatened species, live in isolated populations across Central and West Africa, as well as Uganda and parts of Kenya. The new paper estimates there are more than 5,900 of this species, a significant increase from 2015, when there were 4,780.
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Dave Isay has created a program called "One Small Step" to get Americans from across the political spectrum to stop demonizing one another and start communicating - face to face, one conversation at a time. It has taped more than half a million Americans telling their stories – to become the largest single collection of human voices ever recorded. StoryCorps is an important part of adding history and context and the individuals who make history. Not just the ones that we see on the news, but the people who are part of the fabric of our American life. Around the time of the 2016 presidential election, Dave Isay says he got the idea for a new kind of StoryCorps that could perhaps help unite a country becoming increasingly divided. He decided to call it "One Small Step." "So we match strangers who disagree politically to put them face-to-face for 50 minutes," [said Isay]. "It's not to talk about politics, it's just to talk about your lives." Facilitators begin by asking the participants to read one another's biography out loud. The project tries to match people who may be from different political parties but have something else in common. The format is derived from a psychological concept developed in the 1950s called contact theory. When you have two people who are enemies and you put them face-to-face under very, very specific conditions , and they have a conversation and a kind of visceral, emotional experience with each other, that hate can melt away. And people can see each other in a new way.
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It started last November with a single string of Christmas lights on a Baltimore County street. Kim Morton was home watching a movie with her daughter when she received a text from her neighbor who lives directly across the road. He told her to peek outside. Matt Riggs had hung a string of white Christmas lights, stretching from his home to hers in the Rodgers Forge neighborhood, just north of the Baltimore city line. He also left a tin of homemade cookies on her doorstep. The lights, he told her, were meant to reinforce that they were always connected despite their pandemic isolation. "I was reaching out to Kim to literally brighten her world," said Riggs. He knew his neighbor was facing a dark time. Morton had shared that she was dealing with depression and anxiety. Riggs could relate. A bit of brightness was in order, he decided, but he certainly did not expect that his one strand of Christmas lights would somehow spark a neighborhood-wide movement. Neighbor after neighbor followed suit, stretching lines of Christmas lights from one side of the street to the other. Leabe Commisso ... wanted in. "I said to my neighbor: â€Let's do it, too,' " she recalled. "Before we knew it, we were cleaning out Home Depot of all the lights." Quickly, other neighbors caught on. "Little by little, the whole neighborhood started doing it," said Morton, 49, who has lived in Rodgers Forge for 17 years. "The lights were a physical sign of connection and love." For the first time in a long time, a feeling of togetherness – and light – had returned.
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Tropical forests can bounce back with surprising rapidity, a new study published today suggests. An international group of researchers looking at a number of aspects of tropical forests has found that the potential for regrowth is substantial if they are left untouched by humans for about 20 years. For example, soil takes an average of 10 years to recover its previous status, plant community and animal biodiversity take 60 years, and overall biomass takes a total of 120, according to their calculations." This is due in part to a multidimensional mechanism whereby old forest flora and fauna help a new generation of forest grow – a natural process known as "secondary succession". These new findings ... suggest that it is not too late to undo the damage that humanity has done through catastrophic climate change over the last few decades. "That's good news, because the implication is that, 20 years ... that's a realistic time that I can think of, and that my daughter can think of, and that the policymakers can think of," said Lourens Poorter ... lead author of the paper. This idea of natural regeneration is frequently disregarded in favour of tree plantations, but according to Poorter, the former yields better results than restoration plantings. "Compared to planting new trees, it performs way better in terms of biodiversity, climate change mitigation and recovering nutrients." The takeaway message is that we don't necessarily need to plant more trees when nature is doing it by itself, Poorter said.
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As the year draws to a close, there are reasons to feel cautiously optimistic about areas in which the environment scored victories in 2021. Delayed by a year as a result of COVID-19, November's COP26 - the United Nations Climate Change Conference, held in Glasgow - welcomed the world's second-largest fossil-fuel emitter, the United States, back to the negotiating table after four years of inaction on climate change. By the summit's end, the U.S. and China had made a surprise joint declaration to work together on meeting the goals of the Paris Agreement. The biggest news in forest conservation was the pledge at the UN Climate Conference in Glasgow to end deforestation by 2030; the commitment includes a pledge to provide $12 billion in funding to "help unleash the potential of forests and sustainable land use." The Biden administration spent part of its first year restoring habitat protections that had been rolled back by its predecessor. Perhaps the most prominent was the re-establishment of full protection for the Bears Ears and Grand Staircase-Escalante monuments in southern Utah, as well as the Northeast Canyons and Seamounts National Monument off New England. Populations of some of the world's most iconic species are showing some improvement as a result of protective measures. Humpback whales, whose haunting songs helped build support for the "Save the Whales" campaign that ushered in the modern environmental movement, are increasing in number in many parts of their range.
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Ebony Johnson's enthusiastic service at a Dunkin' location in Ohio is so memorable that regular customer Suzanne Burke noticed when she had not been working the drive-thru for a few weeks in March. When Johnson, 33, returned to work at the Mount Healthy location, where she's been employed for three years, she shared with Burke that she had been struggling financially while also trying to find housing for her and her three children following an eviction. Burke left Johnson a note saying that if Johnson wanted help, Burke would gladly do her best. Johnson accepted, and Burke, who has done work with social services in her career, got to work on reaching out to different businesses and organizations. It all led to a moment nine months in the making on Dec. 3 when Johnson broke down in tears and her young children broke out in smiles when they moved into a fully furnished apartment in Cincinnati. "Oh my God, it was so amazing, I just busted out crying," Johnson said. "I never had a full furnished house. I never had help like this. I had been asking God to put us in a home before Christmas, and He really did. I'm just so thankful." "It was so exciting, we all cried," Burke told TODAY. "I've got three kids, and I can't imagine not having a home to go to and then to have to get up, get the kids to school, and show up at work with a positive, happy attitude? I've been in awe of her." Johnson was able to secure the apartment through the help of the Cincinnati-based organization Strategies to End Homelessness.
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Swastikas on the wall become giant cupcakes with purple icing, and the words "my Hitler" are transformed into "my muffins". All in a day's work for the Italian street artist who fights racism by turning nasty graffiti into food. "I take care of my city by replacing symbols of hate with delicious things to eat," says the 39-year-old artist, whose real name is Pier Paolo Spinazze and whose professional name, Cibo, is the Italian word for food. On a recent sunny morning he had been alerted by one of his 363,000 Instagram followers that there were swastikas and racial slurs in a small tunnel on the outskirts of Verona. Up he turned, wearing his signature straw hat and necklace of stuffed sausages. He took out his bag of spray paints and set to work, while cars drove by beeping. He covered up the slurs with a bright slice of margherita pizza and a caprese salad - mozzarella, tomatoes and basil. A swastika was transformed into a huge red tomato. As he has become a local celebrity in Verona, he has also made enemies: "Cibo sleep with the lights on!" someone spray painted on a wall. He turned the threat into the ingredients of a gnocchi recipe. "Dealing with extremists is never good, because they are violent people, they are used to violence, but they are also cowards and very stupid," Spinazze said. "The important thing is to rediscover values that we may have forgotten, especially anti-fascism and the fight against totalitarian regimes that stem from the Second World War," he said.
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A motorist in the Netherlands sacrificed his own vehicle to save another motorist who was having a seizure on the highway. Henry Temmermans from Nunspeet was driving on the A28 highway near Harderwijk on Friday afternoon when he saw another car driving in the grass on the highway. He peered into her window and realized she was unconscious. "I didn't hesitate for a moment. I had to do something," he [said]. He sped up to get in front of the woman's car and then slowed down so she would crash into him. His plan worked. The woman crashed into the back of his car and came to a complete stop. Behind them was another motorist who managed to record the entire incident on his dashcam. "We both got out immediately. He called 112 and then we looked in the car together," Temmermans said. An ambulance arrived 10 minutes later and took the woman to the hospital. She suffered a few broken ribs but will be okay. Temmermans had to call a [tow] truck as his vehicle was no longer drivable. "The other driver took me home. That turned out to be an old acquaintance from 25 years ago, when we were both young and wild," he said. The next day, the daughter and husband of the woman contacted Temmermans. "They were very grateful to me," he said.
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The U.S. Senate unanimously confirmed Charles "Chuck" Sams III as the next director of the National Park Service on Thursday. He will be the first Native American to lead the agency in its 105-year history. Sams, who is Cayuse and Walla Walla, is a member of the Confederated Tribes of the Umatilla Indian Reservation. The Oregon-based Confederated Tribes is comprised of individuals from the Cayuse, Umatilla and Walla Walla tribes. Sams told the Confederated Tribes' newspaper, the Confederated Umatilla Journal, on Friday that he's "deeply honored" to serve as the 19th director of NPS. "I am also very deeply appreciative of the support, guidance and counsel of my Tribal elders and friends throughout my professional career," Sams told the newspaper. "I look forward to carrying on the responsibility of being a good steward of our natural resources and in joining the dedicated and dynamic staff of the National Park Service." Sams' confirmation marks the first time in nearly five years that the department will have an official director. The position has been filled with various people serving as acting heads since January 2017. Sams has worked in state and tribal governments, as well as in natural resource and conservation management, for more than 25 years. In a press release on Friday, tribal leaders commended the confirmation, with Confederated Tribes trustee member Kat Brigham saying that Sams "knows the outdoors." "He understands the importance of helping families develop a relationship with the land," Brigham said.
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The sweetest Thanksgiving tradition this side of candied yams is back! Jamal Hinton and Wanda Dench will once again get together for the holiday, six years after she accidentally sent him a text inviting him to Thanksgiving dinner, believing she had texted her own grandson. "We are all set for year 6!" Hinton posted Sunday on Twitter, acknowledging that it will be the sixth straight year they have spent Thanksgiving together. He also posted a text message Dench shared inviting him, his girlfriend and his family to dinner. "It would bring my great joy if you, Mikaela and your family would come to my house on Thanksgiving day to share good food and great conversation. Your friend always, Wanda." Hinton, who accepted the invitation, also posted a selfie featuring him and Dench. Hinton and Dench went viral in 2016 after she texted him, saying she's hosting Thanksgiving dinner and would love it if he could attend, thinking she was texting her grandson. They then swapped photos. "You not my grandma," he wrote. "Can I still get a plate tho" Dench didn't miss a beat. "Of course you can," she replied. "That's what grandma's do ...feed every one." Last year, Dench and Hinton (along with Mikaela) met up prior to Thanksgiving, along with a small group of her family, including "the grandson that originally started all of this by changing his phone number and not telling me he changed it," [she said]. "He's changed my life a lot, I know that."
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When Jonathan Tiong was an infant, a neurologist told his parents that he wouldn't live past the age of two. He was diagnosed with type two spinal muscular atrophy, a rare genetic condition that causes muscles to become weak and break down. It is also a progressive disease, meaning he has become ... weaker with time. But in October, the same day he turned 24 years old, he was crowned valedictorian for the National University of Singapore's (NUS) Class of 2021, with the equivalent of a first class honours. He has also landed a prestigious job at sovereign wealth fund GIC, where he currently works full-time as an editorial writer. Speaking to CNA in his home, Mr Tiong candidly described himself as "a very plain and average student" throughout university. In his spare time, he immerses himself in the online game Runescape and watches Twitch streams. He regularly pens columns and blogposts, owing to a love of writing sparked in recent years. "I didn't think I'd be valedictorian for the simple reason that I was not a typical valedictorian. I didn't lead a (co-curricular activity), I wasn't the captain of some sports team, that kind of thing. "I studied a lot, got good grades, but so did a lot of other people. So I didn't really feel outstanding." This is despite the extra challenges he had to grapple with throughout school – namely, fatigue and accessibility in a world mostly built for able-bodied people. Poking fun at NUS' infamously hilly terrain, Mr Tiong joked that the university is also known as the "National University of Stairs".
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With close to two billion dollars devoted to renewable power in the newly passed infrastructure bill, the solar industry is poised for a win. But there have long been some tensions between renewable developers and some farmers. According to NREL, upwards of two million acres of American farmland could be converted to solar in the next decade. But what if it didn't have to be an either or proposition? What if solar panels and farming could literally co-exist, if not even help one another. That was what piqued [Byron] Kominek's interest, especially with so many family farms barely hanging on. Kominek installed the solar panels on one of his pastures. They're spaced far enough apart from one another so he could drive his tractor between them. Still, when it came time to plant earlier this year, Kominek was initially skeptical. But he soon discovered that the shade from the towering panels above the soil actually helped the plants thrive. That intermittent shade also meant a lot less evaporation of coveted irrigation water. And in turn the evaporation actually helped keep the sun-baked solar panels cooler, making them more efficient. By summer, Kominek was a believer. Walking the intricately lined rows of veggies beneath the panels, he beams pointing out where the peppers, tomatoes, squash, pumpkins, lettuces, beets, turnips, carrots were all recently harvested. The farm is still bursting with chard and kale even in November. "Oh yeah, kale never dies," Kominek says, chuckling.
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Kindness is great to give, and especially nice to receive. But isn't something you can see, or touch. So how can science research it? There is a way, and it's concerned with how our brains are behaving when we're doing a good deed for someone else - behaviour that can be recorded and analysed. Have you ever done a selfless act for someone and felt great about it afterwards? That's because part of ... something called the reward pathway. Dr Dan Campbell-Meiklejohn, a senior psychology lecturer ... described that reaction as: "At the moment when you help someone, you donate to charity, etc, the processes that happen in your brain are quite similar to other positive experiences. It activates the reward processing areas of the brain." The brain rewards us for being kind - in the nucleus accumbens - but there is another part where we can learn to be good to others. In 2016, [Dr Patricia Lockwood] led a study at University of Oxford that uncovered a part of the brain which lights up when we help others, compared to when we help ourselves. In the experiment, volunteers made use of a series of symbols. One symbol rewarded them, while another only benefited others. The part of the brain that activated when people deliberately chose to help others is called the subgenual anterior cingulate cortex. When the study was published, it became known as the 'generosity centre'. Dr Lockwood said: "Put another way, the subgenual anterior cingulate seems to be especially tuned to benefiting other people."
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Scientists have developed a novel therapy that promotes recovery from spinal cord injury and reverses paralysis in mice. In the research published in the journal Science ... scientists administered a single injection to tissues surrounding the spinal cords of paralysed mice. Just four weeks later, the rodents could walk again. The therapy, administered in the form of a gel, works by organising molecules at the injury site into a complex network of nanofibers mimicking the natural matrix found in all tissues that play a major role in wound healing and cell to cell communication, the study noted. This gel tunes the motion of molecules at the injury sites, enabling them to find and properly engage with constantly moving receptors on cells, said the researchers. "The key innovation in our research, which has never been done before, is to control the collective motion of more than 100,000 molecules within our nanofibers," study co-author Samuel I Stupp from Northwestern University said. One of the challenges in administering wound healing drugs, the scientists said, is that the receptors sticking out of nerve cells and other types of cells constantly moves around. The novel gel fine-tunes the motion of molecules which "move, â€dance' or even leap temporarily out of these structures", enabling them to connect more effectively with receptors, Dr Stupp explained. With further studies and clinical trials, the scientists believe that the new therapy could be used to prevent paralysis after major trauma.
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Last year, 13-year-old Abraham Olagbegi found out he was born with a rare blood disorder and needed a bone marrow transplant. About a year later, he found out better news: His transplant was successful, and he qualified for Make-A-Wish, an organization that grants wishes to children will serious illnesses. Abraham wanted a long-lasting wish, and he had an idea that he shared with his mom. "I remember we were coming home from one of his doctor appointments and he said, 'Mom, I thought about it, and I really want to feed the homeless,'" Abraham's mom, Miriam Olagbegi, told CBS News. "I said, 'Are you sure Abraham? You could do a lot ... You sure you don't want a PlayStation?'" Unlike many teenage boys, the PlayStation did not entice Abraham. He was sure of his wish to feed the homeless. Abraham's dad thought it was an awesome idea, too, Miriam said. "So, of course, we weren't going to miss an opportunity like that because we always tried to instill giving into our children." In September, Make-A-Wish helped Abraham organize a day to hand out free food in Jackson, Mississippi, with food and supplies donated from local businesses. Abraham said they ended up feeding about 80 people that day. "When the homeless people get the plate, some of them would come back and sing to us and thank us," he said. "And it just really feels good, it warms our hearts. And my parents always taught us that it's a blessing to be a blessing." Make-A-Wish will help Abraham feed the homeless every month for a year.
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Maine voters approved an amendment Tuesday that enshrines the "right to food" – the first of its kind in the United States. The amendment to the state's constitution declares that all people have a "natural, inherent and unalienable right" to grow, raise, produce and consume food of their own choosing as long as they do so within legal parameters. Maine, a state with a bustling agricultural industry, has been at the forefront of the food sovereignty movement, which envisions a food system where producers also have control over how their goods are sold and distributed. The referendum was meant to ensure local communities have more agency over their food supply. "Power over our food supply is concentrated in a few individuals and corporations," [livestock farmer and advocate Heather] Retberg said. "Global companies dominate our food system and policy at the expense of our food self-sufficiency. This concentration of power threatens Mainers' individual rights to grow, raise, harvest, produce, and consume the food of our choosing now and in the future." Maine state Rep. Billy Bob Faulkingham, a Republican legislator who sponsored the legislation, has called it the "Second Amendment of food," empowering people to fight hunger and regain command over the food supply in an era of corporate domination. The nonprofit WhyHunger called the vote "a transformative step in ensuring the protection of food as an unequivocal basic human right."
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At least $1.7bn of funding will be given directly to indigenous peoples and local communities (IPLCs) in recognition of their key role in protecting the planet's lands and forests, it will be announced at Cop26 today. The governments of the UK, US, Germany, Norway and the Netherlands are leading the $1.7bn (Ł1.25bn) funding pledge, which is being announced as part of ambitious global efforts to reverse forest loss and land degradation by 2030, with campaigners cautiously hopeful that this conference of the parties (Cop) could be the first to properly champion indigenous peoples' rights. Tuntiak Katan, a leader of Ecuador's indigenous Shuar people who serves as general coordinator of the Global Alliance of Territorial Communities, said: "We are happy with the financing announcement, but we will be watching for concrete measures that will reveal whether the intent is to transform a system that has directed less than 1% of climate funding to indigenous and local communities. What matters is what happens next." Darren Walker, president of the Ford Foundation, said the aim was to give IPLCs more of a voice in policymaking and discourse. It is hoped more funding will follow. Walker said: "It's a first step, it's a down payment." The money will support IPLCs' capacity to govern themselves collectively, assist with mapping and registration work, back national land reform and help resolve conflict over territories. It will continue until 2025.
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