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Researchers aren't sure why, but in the 23 U.S. states where medical marijuana has been legalized, deaths from opioid overdoses have decreased by almost 25 percent, according to a new analysis. "Most of the discussion on medical marijuana has been about its effect on individuals in terms of reducing pain or other symptoms," said lead author Dr. Marcus Bachhuber. "The unique contribution of our study is the finding that medical marijuana laws and policies may have a broader impact on public health." California, Oregon and Washington first legalized medical marijuana before 1999, with 10 more following suit between then and 2010, the time period of the analysis. Another 10 states and Washington, D.C. adopted similar laws since 2010. For the study, Bachhuber, of the Philadelphia Veterans Affairs Medical Center and the University of Pennsylvania, and his colleagues used state-level death certificate data for all 50 states between 1999 and 2010. In states with a medical marijuana law, overdose deaths from opioids like morphine, oxycodone and heroin decreased by an average of 20 percent after one year, 25 percent by two years and up to 33 percent by years five and six compared to what would have been expected, according to results in JAMA Internal Medicine. Meanwhile, opioid overdose deaths across the country increased dramatically, from 4,030 in 1999 to 16,651 in 2010, according to the Centers for Disease Control and Prevention (CDC). Three of every four of those deaths involved prescription pain medications.
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What should happen if a massive viral outbreak appears out of nowhere and the only possible treatment is an untested drug? And who should receive it? The two American missionaries who contracted the almost-always-fatal virus in West Africa were given access to an experimental drug cocktail called ZMapp. It consists of immune-boosting monoclonal antibodies that were extracted from mice exposed to bits of Ebola DNA. Now in isolation at an Atlanta hospital, they appear to be doing well. It’s an opportunity the 900 Africans who’ve died so far never had. The reasons for different treatment are partly about logistics, partly about economics and, partly about a lack of any standard policy for giving out untested drugs in emergencies. Before this outbreak, ZMapp had only been tested on monkeys. But privileged humans were always going to be the first ones to try it. ZMapp requires a lot of refrigeration and careful handling, plus close monitoring by experienced doctors and scientists—better to try it at a big urban hospital than in rural West Africa, where no such infrastructure exists. And the two Americans who got it in Africa had been infected for more than a week, making its efficacy completely unknown.
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Three of Britain’s leading Ebola specialists have said experimental treatments for the deadly Ebola virus must be offered to the people of West Africa, after two US aid workers were administered with the “cure” in Liberia. The two missionaries, Dr Kent Brantly and Nancy Writebol, are alive and now being cared for at a specialist isolation unit in Atlanta. Though the pair remain weak – and there is no way of knowing at this stage how much of a help the new drug has actually been – the fact that it was given to the two Americans has resulted in widespread criticism and recriminations in West Africa. Almost 900 people have died from the Ebola virus across Guinea, Liberia and Sierra Leone since the latest outbreak began in February this year. Some strains can have fatality rates of up to 90 per cent, though that of the current crisis appears to be around 60 per cent. Now Peter Piot, who discovered Ebola in 1976, David Heymann, the director of the Chatham House Centre on Global Health Security and Jeremy Farrar from the Wellcome Trust have said there are in fact several drugs and vaccines under study that could be used to combat the disease. Liberia’s assistant health minister, Tolbert Nyenswah, said that the news of Dr Brantly and Ms Writebol’s treatment had “made our job very difficult” as dying patients and their relatives in Africa request the same “cure”. The US aid workers were given ZMapp, a drug made from antibodies produced in a lab that has never gone through human trials or been approved by the US’s FDA Food and Drug Administration. Piot, Farrar and Heymann questioned why Africans were not being given the same chance.
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In recent years there has been a jump in the percentage of young people diagnosed with Attention Deficit and Hyperactivity Disorder, commonly known as ADHD: 7.8 percent in 2003 to 9.5 percent in 2007 and to 11 percent in 2011. Angela Hanscom, a pediatric occupational therapist ... suggests [that] more children are being diagnosed with ADHD, whether or not they really have it [because of] the amount of time kids are forced to sit while they are in school. "I recently observed a fifth grade classroom as a favor to a teacher," [Hanscom explains]. "The teacher was reading a book to the children and it was towards the end of the day. Kids were tilting back their chairs back at extreme angles, others were rocking their bodies back and forth, a few were chewing on the ends of their pencils, and one child was hitting a water bottle against her forehead. This was not a special-needs classroom, but a typical classroom. We quickly learned after further testing, that most of the children in the classroom had poor core strength and balance. In fact, we tested a few other classrooms and found that when compared to children from the early 1980s, only one out of twelve children had normal strength and balance. Only one!" Many children are walking around with an underdeveloped vestibular (balance) system today - due to restricted movement. With sensory systems not quite working right, they are asked to sit and pay attention. Children naturally start fidgeting in order to get the movement their body so desperately needs.
Note: Prominent ADHD specialist Keith Connors called increasing ADHD rates "a concoction to justify the giving out of medication at unprecedented and unjustifiable levels" in a 2013 New York Times article. For more along these lines, see concise summaries of deeply revealing health news articles from reliable major media sources. Then explore the excellent, reliable resources provided in our Health Information Center.
Meditating can have an almost instant effect on reducing stress, researchers have found. They say three consecutive days of 25 minute sessions can have a dramatic effect. Researchers studied 'mindful[ness] meditation' - a technique developed in the 1970s. Inspired by ancient Buddhist meditation, mindfulness courses were developed in the late 1970s by US doctors to combat stress. The guiding principle is to live more ‘in the moment’, spending less time going over past stresses and worrying about future problems. Techniques include moving the focus of attention around the body and observing sensations that arise – the so-called ‘body scan’. A secular practice, it is said to help people recognise and overcome negative thoughts while noticing small pleasures. 'More and more people report using meditation practices for stress reduction, but we know very little about how much you need to do for stress reduction and health benefits,' said lead author J. David Creswell. For the study, Creswell and his research team had 66 healthy individuals aged 18-30 years old participate in a three-day experiment. Some participants went through a brief mindfulness meditation training program; for 25 minutes for three consecutive days, the individuals were given breathing exercises to help them monitor their breath and pay attention to their present moment experiences. The participants who received the brief mindfulness meditation training reported reduced stress perceptions to ... speech and math tasks, indicating that the mindfulness meditation fostered psychological stress resilience.
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We have come to think that if something is "in our genes", it is our inevitable destiny. However, this is a gross oversimplification. We have each inherited a particular set of genes, but the outcome of that inheritance is not fixed. Our environment, diet and circumstance flood our bodies with molecules that switch the genes on or off. The result can make a huge difference to our destiny – and that of our descendants. One example of these "epigenetic" changes occurs when a bundle of carbon and hydrogen atoms known as a methyl group attaches itself to the DNA and changes the way its instructions are carried out. Methyl groups often come from what we eat. Lack of food seems to have an epigenetic effect, too. A study of Dutch women starved by the Nazis during the second world war ... found elevated levels of schizophrenia, breast cancer and heart disease. The data suggest that the alterations to which genes are turned on or off survive at least two generations: the one that suffered in the womb during the famine, and their children. They may go much further. A 2011 study published by researchers at the Salk Institute in La Jolla, California, demonstrated epigenetic mutations that lasted for at least 30 generations in plants. What you eat, what your mother ate, the age when your grandfather started smoking, the amount of pollution in your neighbourhood – these factors have all been linked to epigenetic changes that get passed down through the generations. Armed with this new insight, we can take far more control of our health – and the health of future generations.
Note: For a truly engaging and revolutionary book on this topic, read The Biology of Belief by Bruce Lipton, a top researcher in the field of cell biology. For more on this, see concise summaries of deeply revealing health news articles from reliable major media sources.
Elizabeth Holmes founded her revolutionary blood diagnostics company, Theranos, when she was 19. It’s now worth more than $9 billion, and poised to change health care. In the fall of 2003, Elizabeth Holmes, a 19-year-old sophomore at Stanford, plopped herself down in the office of her chemical engineering professor, Channing Robertson, and said, “Let’s start a company.” As a freshman, Holmes had taken Robertson’s seminar on advanced drug-delivery devices–things like patches, pills, and even a contact-lens-like film that secreted glaucoma medication–but now she had invented one the likes of which Robertson had never conceived. It was a wearable patch that, in addition to administering a drug, would monitor variables in the patient’s blood to see if the therapy was having the desired effect, and adjust the dosage accordingly. With Robertson’s blessing, Holmes started her company and, a semester later, dropped out to pursue it full-time. Now she’s 30, and her private, Palo Alto-based corporation, called Theranos–the name is an amalgam of the words “therapy” and “diagnosis”–has 500 employees. Theranos today is a potentially highly disruptive upstart in America’s $73 billion diagnostic-lab industry. It currently offers more than 200–and is ramping up to offer more than 1,000–of the most commonly ordered blood diagnostic tests, all without the need for a syringe. Theranos’s tests can be performed on just a few drops of blood, or about 1/100th to 1/1,000th of the amount that would ordinarily be required–an extraordinary potential boon to frequently tested hospital patients or cancer victims, the elderly, infants, [and] children.
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Why are Americans spending billions on gluten-free products? Is it just a fad or does it make a difference? Perhaps the latter. Several of my patients avoid gluten without any apparent need to do so, and they are convinced their health has improved. One told me that her abdominal bloating, gas and pain have improved. Another says her skin cleared up, and she no longer retains water. Another claims that her "brain fog" is gone, and still another believes that her chronic neck pain due to muscle tension has improved significantly. What are they self-treating? None of them has celiac disease [or] a wheat allergy. They suffer from a syndrome that has yet to be clearly defined. The term "non-celiac gluten sensitivity" (NCGS) appears to be gaining traction. NCGS is what we call a "clinical diagnosis," a syndrome defined by symptoms alone, not by tissue biopsy or blood test. What are the symptoms of NCGS? Abdominal pain, eczema and/or rash, headache, "foggy mind," fatigue, diarrhea, depression, extremity numbness and joint pain. There is nothing unique about these symptoms, which occur in many other conditions. Though the small intestine of those with NCGS looks normal, symptoms appear to go away when gluten is removed from the diet and reappear when gluten is reintroduced. Ultimately, a powerful medical group, such as the American Gastroenterological Association, needs to issue criteria by which someone can be said to have gluten sensitivity.
Note: Some speculate that modern wheat strains, GMOs, and processing methods are behind the increase in gluten sensitivity. For more on this, see this merocla.com article and this article on the history of wheat.
Health care is a tempting target for thieves. Medicaid doles out $415 billion a year; Medicare (a federal scheme for the elderly), nearly $600 billion. Total health spending in America is a massive $2.7 trillion, or 17% of GDP. In 2012 Donald Berwick, a former head of the Centres for Medicare and Medicaid Services (CMS), and Andrew Hackbarth of the RAND Corporation, estimated that fraud ... added as much as $98 billion, or roughly 10%, to annual Medicare and Medicaid spending - and up to $272 billion across the entire health system. Federal prosecutors had over 2,000 health-fraud probes open at the end of 2013. A Medicare “strike force”, which was formed in 2007, boasts of seven nationwide “takedowns”. In the latest, on May 13th, 90 people, including 16 doctors, were rounded up in six cities - more than half of them in Miami, the capital city of medical fraud. Punishments have grown tougher: last year the owner of a mental-health clinic got 30 years for false billing. Yet the sheer volume of transactions makes it easier for miscreants to hide: every day, for instance, Medicare’s contractors process 4.5m claims. In this context the $4.3 billion recovered by fraud-busters in 2013, though a record, looks paltry. Some criminals are switching from cocaine trafficking to prescription-drug fraud because the risk-adjusted rewards are higher. This is the medical world’s “dirty secret”, says John Holcomb of the Texas Medical Association. Everyone talks about it in the doctor’s lounge, but few complain.
Note: For more along these lines, see concise summaries of deeply revealing news articles on corporate corruption and health.
Vermont's governor on [May 8] signed a bill into law that will require the labeling of genetically modified foods -- hailing it as the first such law in the nation. Under the new law, food offered for retail sale that is entirely or partially produced with genetic engineering must be labeled as such by July 2016. "Vermonters take our food and how it is produced seriously, and we believe we have a right to know what's in the food we buy," said Gov. Peter Shumlin. "More than 60 countries have already restricted or labeled these foods, and now one state -- Vermont -- will also ensure that we know what's in the food we buy and serve our families." In the absence of federal action, other states have introduced similar legislation or ballot initiatives, according to the non-profit Center for Food Safety. Maine and Connecticut passed laws requiring labeling, but they won't go into effect until other states pass GMO-labeling laws. Vermont is the first to pass a "no strings attached" bill, the watchdog group said. Supporters of the law expect it will be challenged in court. "I can make no predictions or promises about how the courts will ultimately rule but I can promise that my office will mount a vigorous and zealous defense of the law that has so much support from Vermont consumers," said Vermont Attorney General William Sorrell. The U.S. Department of Agriculture Food Safety and Inspection Service approved a non-GMO label for meat and liquid egg products in June, the first time the department has approved such a label from a third party. GMO foods were approved for human consumption in 1995.
Note: For more on the major risks from GMO foods, see the deeply revealing summary available here. For many major media articles laying bare the serious risks and dangers of GMOs in our food, click here.
If you've never had a heart attack, the FDA says you can put down the aspirin bottle. Taking a daily aspirin is not necessary for people with no history of heart problems, the U.S. Food and Drug Administration says. In a newly released consumer update bound to cause a stir for the 40 million Americans who take aspirin every day, the FDA says it has combed the evidence and concluded that people who have not had heart problems, even if they have a family history of it, will not benefit from taking a daily aspirin. The announcement comes after the FDA denied Bayer’s request to change its aspirin labels to say aspirin can aid in the prevention of heart attacks in people without a history of heart disease. On its website, the FDA has written, “FDA has concluded that the data do not support the use of aspirin as a preventive medication by people who have not had a heart attack, stroke or cardiovascular problems, a use that is called ‘primary prevention.’ In such people, the benefit has not been established but risks — such as dangerous bleeding into the brain or stomach — are still present.” Dr. Robert Temple, deputy director for clinical science at the FDA, said in the recommendation that since the 1990s there has been clinical data showing that people who have undergone a heart attack, stroke or any blood vessel disease in the heart can benefit from taking a daily low dose of aspirin and can lower the risk of having another adverse heart event. This is what the FDA refers to as “secondary prevention.”
Note: Read a mercola.com article on this for more.
Jeffrey M. Smith, author of Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods and founding executive director of The Institute for Responsible Technology, a leading source of GMO-health-risk information, says several animal studies indicate serious health risks associated with genetically modified food, including infertility, immune problems, accelerated aging, faulty insulin regulation and changes in major organs and the gastrointestinal system. In fact, the American Academy of Environmental Medicine has asked physicians to advise all patients to avoid genetically modified foods altogether. Ready to go GMO free? Here are 10 ways to shop smarter: 1. Go organic. The USDA National Organic Standards prohibit GMOs, so shopping organic is a great way to avoid them. 2. Load up on fruits and veggies. Most fresh produce is non-GMO, says Smith, but zucchini, yellow summer squash, edamame, sweet corn and papaya from Hawaii or China are considered high risk and are best avoided. Only buy those high-risk fruits and vegetables if they are labeled "organic" or "non-GMO," he advises. 3. Look for the non-GMO-verified seal. Since GMOs require no labeling, this seal is one of the best ways to tell when foods are free of genetic modification. 4. Join the Tipping Point Campaign. This network of local activists is working to educate communities on the dangers of GMOs. 5. Beware of additives. The five most common GMOs -- corn, canola, soy, cotton and sugar beets -- often end up as additives (in the form of corn syrup, oil, sugar, flavoring agents or thickeners) in packaged foods.
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Katherine Reid, a Bay Area biochemist with a daughter who was autistic, believes she may have found an antidote to the neurodevelopment disorder - and it's as simple as changing a person's diet. It has become increasingly popular for parents of children with autism or attention-deficit/hyperactivity disorder to turn to gluten- and casein-free, or dairy-free, diets in hopes that it will make a difference. But Reid's diet is different. She thinks what it comes down to, at least for some people with autism, is permanently eliminating just a single chemical compound known as monosodium glutamate, or MSG - an ingredient many people associate with Chinese food. Actually, Reid said, the chemical is in nearly every processed food imaginable, but it only appears on food labels as MSG about 1 percent of the time. Instead, MSG is sometimes labeled as flavor or flavoring, soy protein, barley malt, pectin, corn starch or yeast extract, Reid said. "We're getting an abundance of MSG," she said. "It's in 95 percent of processed food. And we don't need it in our diet - ever." While there is no science to back up many of her claims, Reid said the most convincing evidence to her is the results she saw in her daughter. At age 7, Brooke is completely cured, Reid said. [This] persuaded her to quit her high-paying job and help other parents with what she learned, establishing the Fremont nonprofit foundation Unblind My Mind. "Out of the 75 cases of diagnosed autism I've worked on, 74 drastically improved within five weeks," she said.
Note: For more on important health issues, see the deeply revealing reports from reliable major media sources available here.
Take another look at that food label. An ingredient or two may have vanished. As Americans pay closer attention to what they eat, food and beverage companies are learning that unfamiliar ingredients can invite criticism from online petitions and bloggers. The risk of damaging publicity has proven serious enough that some manufacturers have reformulated top-selling products to remove mysterious, unpronounceable components that could draw suspicion. Earlier this year, for example, PepsiCo Inc. said it would stop using brominated vegetable oil in Gatorade and find a another way to evenly distribute color in the sports drink. Last year, Starbucks said it would stop using a red dye made of crushed bugs based on comments it received “through a variety of means,” including an online petition, and switch to a tomato-based extract. Kraft Foods plans to replace artificial dyes with colors derived from natural spices in select varieties of its macaroni and cheese, a nod to the feedback it’s hearing from parents. Ali Dibadj, a Bernstein analyst who covers the packaged food and beverage industry, says the changes reflect a shift from “democratization to activism” by consumers. “It used to be that people would just decide not to buy the product. Now they’re actually agitating for change,” Dibadj said. “There’s a bullhorn — which is the Internet — so you can get a lot of people involved very quickly.” In the past, a customer complaint about an ingredient may have been addressed with a boilerplate letter from corporate headquarters. But now people can go online to share their concerns with thousands of like-minded individuals.
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Baboons vaccinated against whooping cough could still carry the illness in their throats and spread it, research ... has found. The surprising new finding has not been replicated in people, but scientists say it may provide an important clue to a puzzling spike in the incidence of whooping cough across the country, which reached a 50-year high last year. The whooping cough vaccines now in use were introduced in the 1990s after an older version, which offered longer-lasting protection, was found to have side effects. But over the years, scientists have determined that the new vaccines began to lose effectiveness after about five years, a significant problem that many researchers believe has contributed to the significant rise in whooping cough cases. The new study, published ... in Proceedings of the National Academy of Sciences, offers another explanation. Using baboons, the researchers found that recently vaccinated animals continued to carry the infection in their throats. Even though those baboons did not get sick from it, they spread the infection to others that were not vaccinated. “When you’re newly vaccinated you are an asymptomatic carrier, which is good for you, but not for the population,” said Tod J. Merkel, the lead author of the study, who is a researcher in the Office of Vaccines Research and Review in the Food and Drug Administration. The current whooping cough vaccines were developed after a surge in concerns from parents that their children were getting fevers and having seizures after receiving the old vaccine. Those worries added fuel to general skepticism about vaccines that had led some parents to choose not to have their children vaccinated.
Note: For more on the dangers of vaccines, see the deeply revealing reports from reliable major media sources available here.
The public has the right to know what’s in our food. Over 70 percent of processed foods have genetically modified ingredients. GM crops are modified to contain novel patented bacterial and viral DNA never before seen in foods. Not surprisingly, most polls show around 90 percent of the public wants to know which foods are genetically modified. They want the same right to choose as consumers in the 64 countries around the world that mandate some form of labeling of GM foods. Washington state is currently ground zero, with a GM labeling initiative on the Nov. 5 ballot. Chemical and food corporations have raised over $20 million to defeat the measure. They are willing to spend whatever it takes. Last year, the opposition spent over $45 million to narrowly defeat a similar initiative in California. Why are agrichemical companies willing to spend such huge sums to defeat labeling? These companies’ GM foods would not be able to compete in an informed marketplace against non-GM foods. The fact is that, after spending 30 years genetically modifying crops, these companies have failed to come up with a single trait that would attract consumers. GM foods do not have improved nutrition, fewer calories, better taste or lower costs. In other words, they have no market advantage at all. A rational consumer, when faced with a non-genetically engineered bag of corn chips versus a labeled genetically engineered bag would have no incentive to buy the engineered brand. Labeling would expose these companies’ complete failure to provide a single benefit to America’s consumers. The only thing these foods offer is potential risk.
Note: For more on the risks from GMO foods, see the deeply revealing reports from reliable major media sources available here.
Angelina Jolie won plaudits around the world when she announced in May that she’d had a pre-emptive double mastectomy once doctors told her she had a whopping 87 percent risk of developing breast cancer and a 50 percent chance of developing ovarian cancer. Jolie, who regularly leverages her fame for public good, said she chose to share her story in the hope that other women who may be living under the shadow of cancer “will be able to get gene-tested” and know about their “strong options” in the event they’ve been dealt some unlucky genetic cards. While Jolie’s decision to tell the truth about her situation was brave and extraordinarily well intentioned, how much of the truth was she told about her condition? Is her genetic history indeed an automatic death sentence? Here’s what doctors may not have told her. Most breast cancer develops in women without a family history of the disease. The vast majority of women who get cancer (eight out of every nine) don’t have a family history of the disease—and even with a family history, most women will never develop cancer. Four out of five women who have a mother and a sister with breast cancer will never develop the disease, and 12 out of 13 will not die from it. The danger increases with the number of close relatives who have the disease, but the risk may prove to be far less than that described to Jolie. For women who have one close relative with breast cancer, the lifetime risk is 8 percent, which increases to just 13.3 percent for those like Angelina Jolie, with two close relatives who had the disease. There is no solid evidence that just-in-case double mastectomies increase survival.
Note: For more on important health issues, see the deeply revealing reports from reliable major media sources available here.
About half of all Americans take a daily multivitamin as a way to improve their health and cut their risk of diseases. But experts now say that - in almost all cases - the best way to get a full dose of vitamins is from nutritious foods rather than from pills. There is a lot of scientific evidence showing diets rich in produce, nuts, whole grains and fish promote health and decrease risk of heart disease, stroke, diabetes and cancer, according to a new "Vitamins and Minerals" report from Harvard Medical School. On the other hand, studies involving vitamin supplements - and there have been many - show mixed results. In fact, after reviewing a large body of research in 2006, the National Institutes of Health decided not to definitively rule for or against multivitamins' ability to prevent diseases. So what are the quickest ways to boost the vitamin content in your meals? The report identifies about three dozen foods that have the most nutrients per calorie, including avocados, berries, cantaloupe, dark leafy greens, eggs, yogurt, lentils, beans, almonds, fish, chicken and turkey. And although most people think of citrus as the best source of vitamin C, a red pepper has twice as much as an orange. Similarly, potatoes and white beans have more potassium than bananas. The final advice from Dr. Dariush Mozaffarian, the report's editor: "Spend your time and money improving your diet, which is far more likely to pay off in the long run than popping a pill."
Note: The Harvard report can be found here: http://hvrd.me/9Uixox. For a treasure trove of great news articles which will inspire you to make a difference, click here.
The French researcher who caused a scientific storm when he claimed to show that some GM food led to tumours and cancers in rats has accused the UK Food Standards Agency (FSA) of "recklessly endangering public health" by not demanding long-term testing of the foods. In a series of parliamentary and public meetings held this week in London, Edinburgh and Cardiff, Prof Gilles-Eric Séralini has challenged UK politicians and safety authorities to review the way safety is assessed. Séralini, a molecular biologist at Caen University, said: "Our research found severe toxicity from GM maize and [Monsanto pesticide] Roundup. The British Food Standards Agency has uncritically accepted the European Food Safety Authority's dismissal of the study, even though many of EFSA's experts have been exposed as having conflicts of interest with the GM industry. At the very least, the British government should demand long-term mandatory safety testing on all GM foods before they are released onto the market," he said. "The British scientific authorities are deliberately misleading their government and are recklessly endangering public health in ignoring the findings of our research." Séralini's study found that rats developed much higher levels of cancers and died earlier than controls when fed a diet of Monsanto's Roundup-tolerant GM maize NK603 for two years, or were exposed to Roundup over the same period. The usual industry tests last for 90 days.
Note: For more on the risks from GMO foods, see the highly informative summary available here.
We all know exercise promotes health, reducing most people’s risk of developing diabetes and becoming obese. Now light has been shed on how it does this at a cellular level. It seems exercise may be able to drastically alter how genes operate, studies show. Genes are not static. They turn on or off depending on the biochemical signals they receive from elsewhere in the body. One powerful means of affecting gene activity involves a process called methylation, in which methyl groups, a cluster of carbon and hydrogen atoms, attach to the outside of a gene and make it easier or harder for that gene to receive and respond to messages from the body. What is particularly fascinating about the methylation process is that it seems to be driven largely by lifestyle. Diet, for instance, notably affects the methylation of genes. But the role of physical activity in this has been poorly understood. Researchers ... began by recruiting dozens of sedentary but generally healthy adult men. Using new molecular techniques, researchers mapped the methylation patterns on the DNA within [their] cells. Then, under the guidance of a trainer, the volunteers began attending hour-long spin or aerobics classes about twice a week for six months. By the end of that time, the men had ... altered the methylation pattern of many of the genes in their fat cells. More than 17,900 individual sites on 7663 separate genes in the fat cells now displayed changed methylation patterns. Other studies have found that exercise has an equally profound effect on DNA methylation within human muscle cells.
Note: For more on health issues, see the deeply revealing reports from reliable major media sources available here.
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