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A federal court yesterday struck down an Ohio ban on dairy products whose labels say they're made from milk that's free of hormones that increase cows' milk production. That means companies that want to say their products are "rbGH free" and "rbST free" and "artificial hormone free" are now free to do so. The ruling challenges the FDA's 17-year-old finding that there's "no significant difference" between the milk of cows given growth hormone and those that aren't. Just that sort of distinction ... is part of the ongoing debate about how to label genetically engineered salmon. The Court of Appeals for the Sixth Circuit said there is a "compositional difference" between milk from cows given growth hormones and those without. The court gave three reasons they're different: * Increased levels of the hormone IGF-1; * A period of milk with lower nutritional quality during each lactation; and * Increased somatic cell counts (i.e. more pus in the milk). But the FDA concluded in 1993 when it approved the growth hormone that the milk shows "no significant difference" in milk from untreated cows.
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U.S. Army specialist Ethan McCord was one of the first on the scene when a group of suspected insurgents was blown up on a Baghdad street in 2007, hit by 30-mm bursts from an Apache helicopter. "The top of one guy's head was completely off," he recalls. "Another guy was ripped open from groin to neck. A third had lost a leg ... Their insides were out and exposed. I'd never seen anything like this before." Then McCord heard a child crying from a black minivan caught in the barrage. Inside, he found a frightened and wounded girl, perhaps 4. Next to her was a boy of 7 or so, soaked in blood. Their father, McCord says, "was slumped over on his side, like he was trying to protect the children, but he was just destroyed." McCord couldn't look away from the kids. "I started seeing images of my own two children back home in Kansas." McCord Pulled the two kids out of the minivan--the boy was still alive--and helped get them to a hospital. The Apache gunship killed a dozen men, including a pair working for the Reuters news agency; the episode became a video sensation after WikiLeaks released footage of it in April. Back at his base, McCord washed the children's blood off his uniform and body armor. That night, he told his staff sergeant he needed help. "Get the sand out of your vagina," McCord says his sergeant responded. "He told me I was being a homo and needed to suck it up." McCord says he never spoke to anyone about it after that because he didn't want to get in trouble and instead did what soldiers have done forever. "I decided to try to push it down and bottle it up," he says.
The Obama administration is facing internal dissent from its scientists for approving the use of huge quantities of chemical dispersants to tackle the oil spill in the Gulf of Mexico, the Guardian has learned. Jeff Ruch, the exective director of the whistleblower support group Public Employees for Environmental Responsibility, said he had heard from five [EPA] scientists and two other officials who had expressed concerns to their superiors about the use of dispersants. "There was one toxicologist who was very concerned about the underwater application particularly," he said. "The concern was the agency appeared to be flying blind and not consulting its own specialists and even the literature that was available." Veterans of the Exxon Valdez spill questioned the wisdom of trying to break up the oil in the deep water at the same time as trying to skim it on the surface. Other EPA experts raised alarm about the effect of dispersants on seafood. Ruch said EPA experts were being excluded from decision-making on the spill. "Other than a few people in the united command, there is no involvement from the rest of the agency," he said. EPA scientists would not go public for fear of retaliation, he added.
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Researchers have found a drug that can help the brain grow new cells and said their study may lead to ways to improve experimental Alzheimer's drugs. The researchers' work, done on rodents, builds on findings that all mammals, including humans, make brain cells throughout their lives. Most of these die, but this drug helps more of the baby cells survive and grow to become functioning brain cells. "We make new neurons every day in our brain," Andrew Pieper of the University of Texas Southwestern Medical Center in Dallas who worked on the study, said in a telephone interview. "What our compound does is allow more of them to survive." The compound is called P7C3 for now, and the researchers have already started tweaking it to make it more effective. They said it seems safe and appears to work even when taken as a pill. The compound is similar to Medivation Inc and Pfizer Inc's experimental Alzheimer's drug, Dimebon, and may provide ways to improve its effects, Pieper and colleagues reported in the journal Cell. Alzheimer's gradually destroys the brain and affects 26 million people globally. Drugs, such as Pfizer's Aricept, improve symptoms only minimally.
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A top environmental group has sued the U.S. Food and Drug Administration over its failure to regulate bisphenol A, a ubiquitous chemical linked to reproductive harm, cancer and obesity in studies. The Natural Resources Defense Council filed a lawsuit [on June 29] in the U.S. Court of Appeals for the D.C. Circuit arguing that millions of Americans have been unnecessarily exposed to the substance - found in everything from soda bottles and tuna cans to children's sippy cups - in the two years since it first petitioned the agency to outlaw bisphenol A. Under the FDA's own rules, it was required to approve, deny or otherwise respond to the October 2008 petition within 180 days, the lawsuit said. After maintaining for decades that bisphenol A was safe, the FDA reversed position in January, saying exposure to the chemical was of "some concern" for infants and children. The FDA also said it would further study bisphenol A over the next two years. "More research is always welcome and interesting, but at some point you have to say, 'We know enough,' and take action. We've reached that point," said Sarah Janssen, senior scientist at the NRDC's Environment and Public Health program in San Francisco.
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Applying magnets to the brains of Alzheimer's disease sufferers helps them understand what is said to them. The finding by Italian scientsts, who conducted a randomised controlled trial of the treatment, suggests that magnets may alter "cortical activity" in the brain, readjusting unhealthy patterns caused by disease or damage. The study was small, involving just 10 patients, and the results are preliminary. But the scientists from Brescia and Milan say [the results] "hold considerable promise, not only for advancing our understanding of brain plasticity mechanisms, but also for designing new rehabilitation strategies in patients with neurodegenerative disease." Although many may scoff, the capacity of magnets to affect the working of the brain is already well established. Transcranial magnetic stimulation (TMS), the technique investigated by the Italian scientists, has already been shown in separate experiments by British researchers to temporarily stun the part of the brain which controls speech, rendering volunteers unable to utter familiar words. In a similar way, a magnetic wand waved over the left side of the head, can make the right arm jump involuntarily. The excitation of the neuronal pathways that this demonstrates suggests, according to researchers, that the technique might be useful in the rehabilitation of stroke victims.
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Imposing roughly the same cautionary standards for cellphones as for fatty food or sugary soda, this city -- never shy about its opinions -- voted on [June 15] to require all retailers to display the amount of radiation each phone emits. The law -- believed to be the first of its kind in the nation -- came ... amid opposition from the wireless telephone industry, which views the labeling ordinance as a potential business-killing precedent. But the administration of Gavin Newsom, the city's ... mayor ... called the vote a major victory for cell phone shoppers' right to know. Under the law, retailers will be required to post materials -- in at least 11-point type -- next to phones, listing their specific absorption rate, which is the amount of radio waves absorbed into the cellphone user's body tissue. These so-called SAR rates can vary from phone to phone, but all phones sold in the United States must have a SAR rate no greater than 1.6 watts per kilogram, according to the Federal Communications Commission, which regulates the $190 billion wireless industry.
They are the highly trained, generally well-paid employees in the vanguard of American innovation: people who work in biotechnology labs. But the cutting edge can be a risky place to work. The estimated 232,000 employees in the nation’s most sophisticated biotechnology labs work amid imponderable hazards. And some critics say the modern biolab often has fewer federal safety regulations than a typical blue-collar factory. At least three trends are stoking concern among safety advocates. In the wake of the 2001 anthrax attacks, the federal government stepped up research involving biowarfare threats, like anthrax, Ebola and many other of the world’s deadliest pathogens. Another factor is that the new techniques of so-called synthetic biology allow scientists to make wholesale genetic changes in organisms rather than just changing one or two genes, potentially creating new hazards. The third trend involves the shifting focus of the pharmaceuticals industry. Drug makers, responding to competition from cheap generic medications, are moving beyond the traditional business of making pills in chemical factories to focus instead on vaccines and biologic drugs that are made in vats of living cells.
With food stamp use at record highs and climbing every month, a program once scorned as a failed welfare scheme now helps feed one in eight Americans and one in four children. It has grown so rapidly in places so diverse that it is becoming nearly as ordinary as the groceries it buys. More than 36 million people use inconspicuous plastic cards for staples like milk, bread and cheese, swiping them at counters in blighted cities and in suburbs pocked with foreclosure signs. Virtually all have incomes near or below the federal poverty line, but their eclectic ranks testify to the range of people struggling with basic needs. They include single mothers and married couples, the newly jobless and the chronically poor, longtime recipients of welfare checks and workers whose reduced hours or slender wages leave pantries bare. There are 239 counties in the United States where at least a quarter of the population receives food stamps, according to an analysis of local data collected by The New York Times. In more than 750 counties, the program helps feed one in three blacks. In more than 800 counties, it helps feed one in three children. In the Mississippi River cities of St. Louis, Memphis and New Orleans, half of the children or more receive food stamps. Even in Peoria, Ill. — Everytown, U.S.A. — nearly 40 percent of children receive aid. While use is greatest where poverty runs deep, the growth has been especially swift in once-prosperous places hit by the housing bust.
Note: For more from reliable sources on the impacts and realities of the Wall Street financial crisis, click here.
Drug company GlaxoSmithKline has told Canadian doctors to stop using one lot of its H1N1 vaccine until an investigation into a higher-than-expected number of severe allergic reactions is completed. The U.S. vaccine will not be identical to Arepanrix, the GSK H1N1 vaccine used in Canada. Arepanrix contains an adjuvant, a substance designed to boost the immune response, but adjuvants have never been approved for use in U.S. flu vaccines. Almost all of the 172,000 doses in question, distributed the week of Nov. 2 to six Canadian provinces, already have been administered, said Geoffrey Matthews, a spokeswoman for the Public Health Agency of Canada, which, with GSK and Health Canada, is investigating cases of anaphylaxis. Symptoms of anaphylaxis include trouble breathing, chest tightness and swelling of the mouth and throat. Six cases have been reported, Matthews says. In the USA, the Vaccine Adverse Event Reporting System said that as of Nov. 13 it had received 116 reports of serious health events related to the vaccine, including eight deaths – similar to the number in previous years after a similar number of seasonal flu vaccine doses had been shipped.
Note: For lots more on the risks of swine flu vaccines, click here.
LSD, the drug that launched the psychedelic era and became one of the resounding symbols of the counterculture movement of the '60s, is back in the labs. Nearly 40 years after widespread fear over recreational abuse of LSD and other hallucinogens forced dozens of scientists to abandon their work, researchers at a handful of major institutions - including UCSF and Harvard University - are reigniting studies. The study at UCSF ... is looking into the mechanisms of LSD and how it works in the brain. The hope is that such research might support further studies into medical applications of LSD - for chronic headaches, for example - or psychiatric uses. "Psychedelics are in labs all over the world and there's a lot of promise," said Rick Doblin, director of the Multidisciplinary Association for Psychedelic Studies in Santa Cruz. Stanislav Grof was one of the last scientists to abandon hallucinogenic research when he shut down several projects at the Maryland Psychiatric Research Center in 1973 after his funding dried up. He moved to California to work at a research institute in Big Sur, where he turned to studies about how to re-create the effects of those drugs through meditation and breathing techniques. He's pleased to see some of the stigma falling away from drugs like LSD, but it bothers him that the scientific community lost decades of research. "I thought psychiatry and psychology really lost a major opportunity because of the abuse that happened with unsupervised research," Grof said. "These are fascinating substances - and they're very, very powerful, so they should be used with great precaution."
Pharmaceutical companies will be able to produce about 3 billion doses of swine flu vaccine a year ... the World Health Organization said. The U.N. agency had previously predicted that companies would be able to make up to 5 billion doses each year. The World Health Organization admits that not everyone may need vaccination. "Most people will do well without the vaccine," WHO vaccine chief Marie-Paule Kieny told reporters. She said most people infected with the pandemic strain of the H1N1 virus have a mild illness and recover by themselves. Addressing concerns about the safety of the pandemic vaccine, WHO said trials to date suggest it is as safe as a regular seasonal flu shot. Kieny said large-scale vaccination programs would probably detect some cases of severe reaction following the vaccination, but that those would likely have occurred anyway without vaccination. The agency is urging countries to monitor the vaccination procedure for possible further side effects. Meanwhile WHO Director-General Dr. Margaret Chan repeated Thursday her recommendation that governments keep up their guard against swine flu but refrain from closing borders or restricting trade.
Note: With the cost of a regular flu vaccine dose ranging from about $20 to $30, do you think the pharmaceutical companies have any vested interest in the public being vaccinated? Let's see, 3 billion X $20 = $60 billion. Hmm. For more on the danger of this vaccine and rampant fear mongering, click here and here.
To the credit of opponents of health-care reform, the lies and exaggerations they're spreading are not made up out of whole cloth—which makes the misinformation that much more credible. Instead, because opponents demand that everyone within earshot (or e-mail range) look, say, "at page 425 of the House bill!," the lies take on a patina of credibility. Take the claim in one chain e-mail that the government will have electronic access to everyone's bank account, implying that the Feds will rob you blind. The 1,017-page bill passed by the House Ways and Means Committee does call for electronic fund transfers—but from insurers to doctors and other providers. There is zero provision to include patients in any such system. Five other myths that won't die: [1] You'll have no choice in what health benefits you receive. [2] No chemo for older Medicare patients. A related myth is that health-care reform will be financed through $500 billion in Medicare cuts. This refers to proposed decreases in Medicare increases. [3] Illegal immigrants will get free health insurance. [4] Death panels will decide who lives. [5] The government will set doctors' wages. To be sure, there are also honest and principled objections to health-care reform. Some oppose a requirement that everyone have health insurance as an erosion of individual liberty. And many are simply scared out of their wits about what health-care reform will mean for them. But when fear and loathing hijack the brain, anything becomes believable.
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Pharmaceutical firms need incentives, including lucrative patents, to keep creating drugs and vaccines against emergent threats such as the H1N1 influenza pandemic, the World Health Organization's head said on Tuesday. "Progress in public health depends on innovation. Some of the greatest strides forward for health have followed the development and introduction of new medicines and vaccines," said WHO Director-General Margaret Chan said. Chan, who last month declared a full pandemic underway from the H1N1 virus, said that patents can help ensure that companies develop medicines to "stay ahead of the development of drug resistance" in diseases like malaria and tuberculosis. The discovery of isolated H1N1 infections that resist the anti-viral Tamiflu, made by Roche and Gilead, and the global scramble to secure flu vaccines have shown the importance of robust research and development, Chan said. "Innovation is needed to keep pace with the emergence of new diseases, including pandemic influenza caused by the new H1N1 virus," she told a meeting on intellectual property and health, a contentious issue that has divided rich and poor nations.
Note: How much more blatant can it get? The WHO is telling us to pump money into the corrupt pharmaceutical corporations, who make huge profits from fear mongering and health disasters. When profit drives the health industry, which do you think comes first, money or public health? For lots more revealing, reliable information on the fear-mongering around swine flu, click here and here.
In a sweeping critique ... an expert panel of the National Research Council said the federal government was not doing enough to identify potential health and environmental risks from engineered nanomaterials. Nanomaterials are engineered on the scale of a billionth of a meter, perhaps 1/10,000 the width of a human hair. They are turning up in a range of items including consumer products like toothpaste and tennis rackets and industrial products like degreasers or adhesives. But some experts say they may pose health or environmental risks. For example, researchers in Scotland reported this year that carbon nanotubes may pose the same health risks as asbestos. “Industry wants to run with it,” said Andrew D. Maynard, chief science adviser to the Project on Emerging Nanotechnologies at the Woodrow Wilson Institute, who was the chairman of the panel. But he added, “one of the big barriers at the moment is understanding how to use it safely.” The panel analyzed the risk research strategy of the National Nanotechnology Initiative, the program to coordinate federal efforts in nanotechnology research and development. Its report concluded that the initiative’s strategy “does not present a vision, contain a clear set of goals, have a plan of action for how the goals are to be achieved, or describe mechanisms to review and evaluate funded research and assess whether progress has been achieved.” An informal coalition of environmental and business organizations praised the report, saying that for three years they had been urging the federal government to do more to assess potential health and environmental effects of nanomaterials.
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What do you do when one arm of the government says everything is O.K. and another tells you to watch out? That is what is happening with bisphenol-A — a chemical used in many plastics and epoxy resins now found in baby bottles and liners for canned goods. The answer is a truism in every family rulebook — when in doubt, especially when it comes to children, err on the side of caution. That means it is a good idea to keep the young away from bisphenol-A, or BPA. Then this week, the National Toxicology Program, the federal agency for toxicological research, reported that their research shows “some concern” about the effects of BPA on the brain development and behavior of fetuses and young children. A new study by the Yale School of Medicine is cause for even more concern. In tests on primates, researchers found that BPA “causes the loss of connections between brain cells” that could cause memory or learning problems and depression.” John Bucher, the associate director of the toxicology program, said ... "We have concluded that the possibility that BPA may affect human development cannot be dismissed.”
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What would you do if had an incurable disease and heard that something simple and common may help -- a chemical found at a pet store, or in an allergy drug, or a breakthrough injection a man in California developed? It's the sort of dilemma Alan Romantowski, a former airline pilot, faces with each news story about Alzheimer's disease treatments. "It is tempting; I'm taking ginseng, fish oil, ginkgo and all the over-the-counter things that the doctors say don't have any proof that it helps, but it doesn't hurt," said Romantowski, 55, who is suffering from the early stages of the disease. Whether scientifically sound or wacky, any news about potential Alzheimer's treatments can fill a doctor's voicemail with calls from desperate families. And a new potential treatment announced Tuesday may be no exception. Discussed at the annual Alzheimer's Association Meeting in Chicago, a drug called Rember sparked hope among researchers and within the Alzheimer community. Rember has completed a phase II trial, which means it's a long way off from meeting FDA approval as a legal therapy. But, thus far the data has shown promise -- double the improvement in cognition than a placebo gives for patients with moderate Alzheimer's disease. "There was an article about that in our paper this morning," said Josie Romantowski. "I actually even called my husband about it... as far as trying [a drug], what is there to lose really, at this point?"
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While carrying out field work in Papua New Guinea in the late 1980s, [Dr. David Pritchard] noticed that Papuans infected with the Necator americanus hookworm, a parasite that lives in the human gut, did not suffer much from an assortment of autoimmune-related illnesses, including hay fever and asthma. Over the years, Dr. Pritchard has developed a theory to explain the phenomenon. "The allergic response evolved to help expel parasites, and we think the worms have found a way of switching off the immune system in order to survive," he said. "That's why infected people have fewer allergic symptoms." To test his theory, and to see whether he can translate it into therapeutic pay dirt, Dr. Pritchard is recruiting clinical trial participants willing to be infected with 10 hookworms each in hopes of banishing their allergies and asthma. Never one to sidestep his own experimental cures, Dr. Pritchard initially used himself as a subject. After Dr. Pritchard's self-infection experiment, the National Health Services ethics committee let him conduct a study in 2006 with 30 participants, 15 of whom received 10 hookworms each. Tests showed that after six weeks, the T-cells of the 15 worm recipients began to produce lower levels of chemicals associated with inflammatory response, indicating that their immune systems were more suppressed than those of the 15 placebo recipients. Despite playing host to small numbers of parasites, worm recipients reported little discomfort. Trial participants raved about their allergy symptoms disappearing.
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Smokers trying to quit sometimes use nicotine patches to fight their tobacco dependence. But patches don't work for everyone. New research suggests that patches might be made more effective if used in combination with hypnosis, just as they tend to work better when used in conjunction with professional counseling. A recently published study showed hypnotherapy to be as effective as standard behavioral counseling when combined with nicotine patches in helping smokers to quit and stay off cigarettes for one year. "This study provides much-needed evidence that hypnosis is indeed a very helpful treatment," says lead author Timothy Carmody. During hypnotherapy, Carmody explained, patients are coaxed into a relaxed state and then provided with a series of skills for coping with withdrawal symptoms and the urge to smoke. A total of 286 participants were randomly divided and received either hypnosis or standard behavioral counseling aimed at smoking cessation. Hypnosis was particularly helpful for would-be quitters who reported a history of depression. That finding suggests that smokers who have struggled with depression—or perhaps with other psychiatric conditions, Carmody says—might someday receive hypnosis as part of the quitting process. Brian Hitsman, assistant professor of preventive medicine at Northwestern University's Feinberg School of Medicine, called the results encouraging and added that the hypnotic intervention evaluated in the study may have the potential to serve as another nonpharmacological treatment option in addition to standard counseling.
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A man who had been given less than a year to live had a complete remission of advanced deadly skin cancer after an experimental treatment that revved up his immune system to fight the tumors. The 52-year-old patient's dramatic turnaround was the only success in a small study, leading doctors to be cautious in their enthusiasm. However, the treatment reported in ... The New England Journal of Medicine is being counted as the latest in a small series of successes involving immune-priming treatments against deadly skin cancers. "Immunotherapy has become the most promising approach" to late-stage, death-sentence skin cancers, said Dr. Darrell Rigel, a dermatology researcher at the New York University Cancer Institute in New York. About 20 years ago, some scientists discovered that immune cells could latch onto and attack skin cancers. "There's a long history behind all of this," said Dr. Steven Rosenberg of the National Cancer Institute. In recent experiments, Rosenberg and other researchers have focused on souping up a certain kind of immune system cell - the "killer T cells" that envelop and kill foreign agents. Scientists focused ... on specific helper T cells that are adept at locking onto a cancer cell and guiding the killer cells to their target. The researchers drew blood from patients, located the special helper cells and then grew more of them in the laboratory. They then infused roughly 5 billion of the cells back into the patients without chemotherapy or the other harsh drugs. "It's a simpler and less toxic approach to melanoma than had been previously employed," said Dr. Louis Weiner, director of the cancer center at Georgetown University.
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