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Scientists in China have genetically modified human embryos in a world first. The Chinese group used a genome editing procedure called Crispr to modify an aberrant gene that causes beta-thalassaemia, a life-threatening blood disorder, in faulty IVF embryos obtained from local fertility clinics. The team, led by Junjiu Huang at Sun Yat-sen University in Guangzhou, is the first to publish such work, confirming rumours that have been circulating for months that human embryos had been modified in China. The work is described in the journal Protein and Cell. Two prominent journals, Nature and Science, rejected the paper citing ethical objections, Huang said. Last month, researchers writing in Nature called for a global moratorium on the genetic modification of human embryos, citing “grave concerns” over the ethics and safety. They added that any therapeutic benefits were tenuous. Genetic modification of the DNA in human embryos would not only affect the individual but their children and their children’s children and so on down the generations. That could halt the inheritance of genetic diseases that run in families, but it could also pass on unforeseen medical problems that the procedures may cause. One of the main safety concerns with genome editing is the risk of changes being made to healthy genes by accident. These so-called “off-target” edits happened far more than expected in Huang’s study, suggesting that the procedure they used is far from safe.
Note: The negative effects of generically modified foods on health are becoming clear. What will happen if our human gene-pool is similarly tinkered with?
NutraSweet says it will no longer make the artificial sweetener aspartame as a result of foreign competition. The privately held company said Wednesday it expects to shut down a major portion of a plant that employs about 210 workers, including contractors, by year-end as a result. That will leave it with only about 10 to 20 employees to focus on its two other smaller sweeteners, the company said. "Low-cost imports now dominate the aspartame market, making it impossible for us to sustain a profitable business while maintaining our unmatched standard of quality," NutraSweet CEO William DeFer said in a statement. Aspartame is more commonly known as the ingredient used in Equal, the blue packets of sweetener often found on tables at restaurants. NutraSweet spokesman Hud Englehart said the company started facing competition as a supplier of aspartame once its patents on the artificial sweetener expired.
Note: This article fails to mention anything about the serious risks and dangers of aspartame which have been exposed by top doctors and scientists. See the powerful documentary "Sweet Misery" on this which has saved many lives. For more on health corruption and manipulation, see concise summaries of deeply revealing health news articles from reliable major media sources.
Women diagnosed with early-stage cancer in one breast are increasingly choosing to have both breasts removed to reduce their chances of getting cancer again, but they'll likely have no better chance at long-term survival than those who had a far less invasive lumpectomy followed by radiation, researchers said [on September 2]. Researchers at Stanford University and the Cancer Prevention Institute of California in Fremont reached the conclusion after taking the largest and perhaps most comprehensive look at the survival rates for the most common surgical choices for early-stage breast cancer: double mastectomy, a single mastectomy and lumpectomy followed by radiation. "We thought we'd maybe see some survival benefit with bilateral mastectomy, particularly in younger women," said Dr. Allison Kurian, assistant professor of health research and policy at Stanford and lead author of the study. "We looked and looked, and saw no difference there." For their study, the researchers relied on data from the California Cancer Registry, which involved nearly 190,000 cases or virtually every woman in California diagnosed with one cancerous tumor in a single breast between 1998 and 2011. More than half were treated with lumpectomies, which involve removing just the tumor and surrounding tissue. The study showed the rate of bilateral mastectomies rose from 2 percent of all patients in 1998 to 12.3 percent in 2011, an increase most pronounced in younger white women. In that group, the percentage of patients younger than 40 choosing to have both breasts removed skyrocketed from 3.6 percent in 1998 to 33 percent in 2011.
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It sounds counterintuitive: Researchers found rates of the most common type of thyroid cancer had tripled since the 1970s, but they weren't particularly alarmed. That's because they say the problem is rooted in the way we diagnose the disease rather than the cancer itself. In essence, technology is allowing us to find tiny tumors that may never even go on to cause symptoms, let alone death. The study ... found that despite the threefold increase from 1975 to 2009 in this particular form of thyroid cancer, mortality rates have remained unchanged. Add papillary thyroid cancer to the list of cancers that more and more researchers believe may [be] overdiagnosed because of overzealous screenings and advanced technologies. Other studies have suggested this problem may include such conditions as slow-growing prostate cancer and precancerous ductal carcinoma in situ, or DCIS, of the breast. The concern among the researchers is that treatment of these diseases may cause more patient harm than the disease itself. "In the last few years, the tide has turned. People are recognizing overdiagnosis more and more," said Dr. Louise Davies, the thyroid cancer study's author. The disease in the thyroid ... is often detected incidentally, meaning that it's discovered during a scan for something else or picked up during a routine exam. "The cancers that are picked up incidentally are not causing symptoms and are small. Those are the ones that are probably not going to be a problem," said Davies. "The risk of death from thyroid cancer is very, very small ... but it's not zero."
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The British drug maker GlaxoSmithKline will no longer pay doctors to promote its products and will stop tying compensation of sales representatives to the number of prescriptions doctors write, its chief executive said ..., effectively ending two common industry practices that critics have long assailed as troublesome conflicts of interest. The announcement appears to be a first for a major drug company — although others may be considering similar moves — and it comes at a particularly sensitive time for Glaxo. It is the subject of a bribery investigation in China, where authorities contend the company funneled illegal payments to doctors and government officials in an effort to lift drug sales. For decades, pharmaceutical companies have paid doctors to speak on their behalf at conferences and other meetings of medical professionals, on the assumption that the doctors are most likely to value the advice of trusted peers. But the practice has also been criticized by those who question whether it unduly influences the information doctors give each other and can lead them to prescribe drugs inappropriately to patients. Under the plan, which Glaxo said would be completed worldwide by 2016, the company will no longer pay health care professionals to speak on its behalf about its products or the diseases they treat “to audiences who can prescribe or influence prescribing.” It will also stop providing financial support directly to doctors to attend medical conferences, a practice that is prohibited in the United States through an industry-imposed ethics code but that still occurs in other countries.
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China recently rejected a 60,000-ton shipment of American corn because it included unapproved genetically modified grain, the country’s food-quality watchdog said. The shipment was halted in the southern port city of Shenzhen, near Hong Kong, after it was discovered to contain MIR162, a special insect-resistant variety of maize developed by Syngenta, a Swiss maker of seeds and pesticides, according to Chinese state media. MIR162 is not on the Chinese government's short list of approved grains considered genetically modified organisms, or GMO. Still, Chinese consumers remain wary of GMO crops and some nationalist-leaning pundits have suggested the Western-dominated technology leaves China’s food supply vulnerable. The U.S. is the world’s largest corn exporter and China is its No. 3 customer. The Asian nation is expected to buy a record 7 million tons of corn in the 2013-14 marketing year. Experts described the recent rejection of U.S. corn as probably an isolated incident and said China would continue with its buying binge.
Note: For more on the risks from genetically-modified organisms in food and the environment, see the deeply revealing reports from reliable major media sources available here.
The Centers for Disease Control on [September 16] confirmed a link between routine use of antibiotics in livestock and growing bacterial resistance that is killing at least 23,000 people a year. The report is the first by the government to estimate how many people die annually of infections that no longer respond to antibiotics because of overuse in people and animals. CDC Director Thomas Frieden called for urgent steps to scale back and monitor use, or risk reverting to an era when common bacterial infections of the urinary tract, bloodstream, respiratory system and skin routinely killed and maimed. "We will soon be in a post-antibiotic era if we're not careful," Frieden said. "For some patients and some microbes, we are already there." Along with the annual fatalities, the report estimated at least 2 million antibiotic-resistant infections occur each year. Frieden said these are "minimal estimates" because they count only microbes that are resistant to multiple antibiotics and include only hospital infections, omitting cases from dialysis centers, nursing homes and other medical settings. At least 70 percent of all antibiotics in the United States are used to speed growth of farm animals or to prevent diseases among animals raised in feedlots. Routine low doses administered to large numbers of animals provide ideal conditions for microbes to develop resistance.
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Are the colored additives used in Kraft's popular Macaroni & Cheese products dangerous? That's what two food bloggers are alleging in their petition to Kraft Foods to remove Yellow No. 5 and Yellow No. 6 from the blue-boxed pantry staples. Yellow Nos. 5 and 6 are used to color beverages, dessert powders, candy, ice cream, custards and other foods. Vani Hari, from the blog Food Babe, and Lisa Leake, from 100 Days of Real Food, have taken to Change.org to petition Kraft's management to remove the dyes, saying they may potentially cause health problems and are not included in Kraft's Mac & Cheese products sold in the United Kingdom. "Kraft reformulated their product for the UK, but not for their fellow American citizens," they argued. At press time, the petition had nearly 135,000 signatures. The Center for Science in the Public Interest, a consumer advocacy group, has been petitioning to ban food dyes in the U.S. for years. In a 2010 report called Food Dyes: A Rainbow of Risks, the CSPI says Yellow Nos. 5 and 6 can cause hypersensitivity, or allergic reactions, and contain carcinogens called Benzidine and 4-amino-biphenyl. Some studies reported hyperactivity in children associated with Yellow 5 intake or genotoxicity -- or damage to cellular DNA -- says CSPI. Yellow 5 is the most widely used food dye after Red 40, according to CSPI.
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A new laboratory analysis of eight prescription drugs that expired between 28 and 40 years ago has found that most have remained just as potent as they were on the day they were made. Overall, the eight drugs included 14 different active ingredients, including aspirin, codeine and hydrocodone. In 86% of cases, the study found, the amount of active ingredient present in the drugs was at least 90% of the amount indicated on the label. That falls within the range deemed acceptable by the Food and Drug Administration. It's impossible to say from the study results alone whether the eight drugs would be effective if used today, but "there's no reason to think that they're not," says Lee Cantrell, the lead author of the study and a professor of clinical pharmacy at the University of California, San Francisco. Most drugs are dated to expire after one to five years, but as the results show, that time frame doesn't necessarily correlate to a drug's potency, Cantrell says. "All [the expiration date] means from the manufacturers' standpoint is that they're willing to guarantee the potency and efficacy for the drug for that long," he says. "It has nothing to do with the actual shelf life." "We're spending billions and billions on medications and medication turnover," Cantrell says. "If a drug has expired, you've got to throw it away, it goes into a landfill, and you have to get a new prescription. This could potentially have a significant impact on cost."
Note: A Wall Street Journal article from the year 2000 also concluded that many drugs last far longer than their expiration dates. Read it at this link.
A New Orleans law firm is challenging government assurances that Gulf Coast seafood is safe to eat in the wake of the BP oil spill, saying it poses “a significant danger to public health.” Citing what the law firm calls a state-of-the-art laboratory analysis, toxicologists, chemists and marine biologists retained by the firm of environmental attorney Stuart Smith contend that the government seafood testing program, which has focused on ensuring the seafood was free of the cancer-causing components of crude oil, has overlooked other harmful elements. And they say that their own testing — examining fewer samples but more comprehensively — shows high levels of hydrocarbons from the BP spill that are associated with liver damage. “What we have found is that FDA simply overlooked an important aspect of safety in their protocol,” contends William Sawyer, a Florida-based toxicologist on Smith’s team. Five months after crude oil stopped gushing from the broken BP wellhead into the Gulf of Mexico, the federal government has reopened more than 90 percent of fishing waters that were in danger of contamination from the broken Deepwater Horizon rig. But many fishermen have yet to return to sea, and consumer confidence in Gulf seafood remains lukewarm.
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Nearly a million workers won't get a consumer protection in the U.S. health reform law meant to cap insurance costs because the government exempted their employers. Thirty companies and organizations, including McDonald's and Jack in the Box, won't be required to raise the minimum annual benefit included in low-cost health plans, which are often used to cover part-time or low-wage employees. The Department of Health and Human Services, which provided a list of exemptions, said it granted waivers in late September so workers with such plans wouldn't lose coverage from employers who might choose instead to drop health insurance altogether. Without waivers, companies would have had to provide a minimum of $750,000 in coverage next year, increasing to $1.25 million in 2012, $2 million in 2013 and unlimited in 2014.
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A new study has suggested that cell phone radiation may be contributing to declines in bee populations in some areas of the world. Bee populations dropped 17 percent in the UK last year, according to the British Bee Association, and nearly 30 percent in the United States says the U.S. Department of Agriculture. Parasitic mites called varroa, agricultural pesticides and the effects of climate change have all been implicated in what has been dubbed "colony collapse disorder" (CCD). But researchers in India believe cell phones could also be to blame for some of the losses. In a study at Panjab University in Chandigarh, northern India, researchers fitted cell phones to a hive and powered them up for two fifteen-minute periods each day. After three months, they found the bees stopped producing honey, egg production by the queen bee halved, and the size of the hive dramatically reduced. It's not just the honey that will be lost if populations plummet further. Bees are estimated to pollinate 90 commercial crops worldwide. Their economic value in the UK is estimated to be $290 million per year and around $12 billion in the U.S..
Billionaire Mayor Michael Bloomberg defended multibillion-dollar pharmaceutical companies and their chief executives on Friday, declaring that they "don't make a lot of money" and shouldn't be scapegoats in the health care debate. The mayor — and wealthiest person in New York City with a fortune estimated at $16.5 billion — made the comments on his radio show Friday. "You know, last time I checked, pharmaceutical companies don't make a lot of money, their executives don't make a lot of money," Bloomberg said. Pharmaceutical CEOs are known to make millions, with generous salaries, stock options and other perks. Abbott Laboratories Inc. Chairman and Chief Executive Miles White's compensation was $25.3 million in 2008. The North Chicago, Ill.-based company saw profit rising 35 percent to $4.88 billion. Merck & Co.'s chief executive, Richard T. Clark, received a $17.3 million compensation package for 2008. The company's profit more than doubled to $7.8 billion. The mayor ... often battles criticism that he is out of touch with regular people. Earlier this year he declared "we love the rich people" while arguing against raising taxes on the wealthy. It was clear that Bloomberg or one of his aides realized his gaffe while he was still on the air Friday. The mayor, who has sought to cast himself as a financial and business expert, came back from a break and said he had looked up the pay of some pharmaceutical executives. "Some of them are making a decent amount, more than a decent amount of money," he said.
The new H1N1 influenza virus bears a disturbing resemblance to the virus strain that caused the 1918 flu pandemic, with a greater ability to infect the lungs than common seasonal flu viruses, researchers reported on Monday. Separately, a top official at the World Health Organization said Monday a fully licensed swine flu vaccine might not be available until the end of the year. The report could affect many countries' vaccination plans. But countries could use emergency provisions to get the vaccines out quicker if they decide their populations need them. The swine flu viruses currently being used to develop a vaccine aren't producing enough of the ingredient needed for the vaccine, and WHO has asked its laboratory network to produce a new set of viruses as soon as possible. Other tests showed the virus could be controlled by the antiviral drugs Relenza, made by GlaxoSmithKline, and Tamiflu, made by Roche AG, the researchers said. The World Health Organization said on Monday that vaccine makers should start making immunizations against H1N1 and that healthcare workers should be first in line to get them. The WHO has previously estimated that the world could have as many as 4.9 billion doses of H1N1 swine flu vaccine ready for the next flu season — but this assumes people only need one shot and production yields are similar to seasonal vaccine.
Note: Who's making the big bucks here? Why is the WHO so strongly promoting billions of doses of vaccines for a disease in which the vast majority of the relatively few people who have died had underlying causes. For more on the blatant corruption of our health industry from reliable sources, click here and here.
Miami International Airport [MIA] and 18 other major American airports have been lined up to handle a future pandemic that could require them to quarantine international flights. The U.S. Centers for Disease Control and Prevention has set up stand-by quarantine/screening facilities at the 19 airports to which all flights from affected countries would be diverted. Nationally, airline and airport lobbyists predict chaos, saying there is no way the air-traffic system can handle such extensive rerouting. Now, new proposals are emerging in Washington, including one that would designate Fort Lauderdale-Hollywood, Orlando International and four other major airports as potential second-tier quarantine sites. Local officials say they understand the CDC will approve the new designations only if the airports pay for the quarantine facilities themselves. The CDC would pay for the quarantine stations at the 19 primary airports. The facilities are not cheap. A 2008 study by the Federal Aviation Administration concluded that setting aside space for health screenings and a quarantine of up to 200 people could cost $15,000 a month, with costs of an actual quarantine running into the hundreds of thousands of dollars. Fort Lauderdale-Hollywood officials began developing a plan to handle quarantined passengers and flights several years ago during the bird flu scare. It calls for erecting air-conditioned tents on the runway ramps to screen or quarantine passengers before they enter the terminal. Quarantined passengers might have to remain for days to show they are not infectious.
After a century of declines, the U.S. infant mortality rate barely budged between 2000 and 2005, causing the United States to slip further behind other developed countries despite spending more on healthcare, according to a report released Wednesday. The rate was 6.86 infant deaths per 1,000 live births in 2005, virtually unchanged from 6.89 in 2000. In 1900, the rate was 100 deaths per 1,000 live births. The United States dropped to 29th in the world in infant mortality in 2004, the latest year for which data are available from all countries, tying with Poland and Slovakia. The year before, it was 27th. In 1960, it was 12th. The report from the Centers for Disease Control and Prevention attributed the leveling off in mortality to a 9% increase in premature births over the same period and to stalled progress in saving the earliest preterm infants. Premature birth and low birth weight are by far the biggest causes of infant death. Infant mortality rates vary by race and ethnicity, from a high of 13.63 per 1,000 births for African American women to a low of 4.42 for Cuban Americans, according to the CDC report. Differences in socioeconomic status and access to medical care did not entirely explain the gap, the report said. Premature births are increasing, possibly tied to rising rates of obesity, diabetes and hypertension. What those conditions have in common is that they are preventable, and that ... is where the United States falls behind other developed countries.
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Mobile phones DO increase the risk of brain cancer, scientists claimed yesterday. The chances of developing a malignant tumour are "significantly increased" for people who use a mobile for ten years. The shock finding is the result of the biggest ever study by the International Agency for Research on Cancer, part of the World Health Organisation. Scientists found a type of brain tumour called glioma is more likely in long-term mobile users. French experts analysed data from 13 countries, including Britain. They cross-referenced various types of tumours with mobile use. Researchers admit the cause is unknown, but it is thought radiation from handsets could be the trigger. Study chief Professor Elisabeth Cardis said: "To underestimate the risk would be a complete disaster." Last night a British expert insisted mobiles are not dangerous. Professor Patricia McKinney of the University of Leeds said: "Reasonable use is unlikely to increase the risk of tumours."
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A new study from researchers at the University of Ottawa shows honey to be effective in killing bacteria that cause chronic sinusitis [which] affects millions of people every year. In chronic sinusitis, the mucous membranes in the sinus cavities become inflamed, causing headaches, stuffy nose, and difficulty breathing. Though it can be caused by allergies, chronic sinusitis can also be caused by bacteria that colonize in the nose and sinuses. That's where honey may help. Researchers, led by Tala Alandejani, MD, at the University of Ottawa, tested two honeys, manuka and sidr. [They] singled out three particularly nasty bacteria: two strains of staph bacteria ... and one called Pseudomonas aeriginosa. The two types of honey were effective in killing the bacteria. Even bacteria growing in a biofilm, a thin, slimy layer formed by bacteria that affords resistance to antibiotics, were susceptible to honey. The researchers also found that the two types of honey worked significantly better than an antibiotic against [the staph bacterias]. Scientists hope the results can help lead to a new treatment for people with chronic sinusitis.
Note: One note of caution: Infants one year or younger should never be given honey because it could become toxic in their underformed intestinal tract, causing illness or even death.
In 2002, at a Johns Hopkins University laboratory, a business consultant named Dede Osborn took a psychedelic drug as part of a research project. She felt like she was taking off. She saw colors. Then it felt like her heart was ripping open. But she called the experience joyful as well as painful, and says that it has helped her to this day. "I feel more centered in who I am and what I'm doing," said Osborn, now 66, of Providence, R.I. "I don't seem to have those self-doubts like I used to have. I feel much more grounded (and feel that) we are all connected." Scientists reported ... that when they surveyed volunteers 14 months after they took the drug, most said they were still feeling and behaving better because of the experience. Two-thirds of them also said the drug had produced one of the five most spiritually significant experiences they'd ever had. The drug, psilocybin, is found in so-called "magic mushrooms." It's illegal, but it has been used in religious ceremonies for centuries. The project made headlines in 2006 when researchers published their report on how the volunteers felt just two months after taking the drug. The new study followed them up [to] a year after that. Fourteen months after taking the drug, 64 percent of the volunteers said they still felt at least a moderate increase in well-being or life satisfaction, in terms of things like feeling more creative, self-confident, flexible and optimistic. The questionnaire answers indicated lasting gains in traits like being more sensitive, tolerant, loving and compassionate.
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A new analysis concludes that the Food and Drug Administration approved experiments with artificial blood substitutes even after studies showed that the controversial products posed a clear risk of causing heart attacks and death. The review of combined data from more than 3,711 patients who participated in 16 studies testing five different types of artificial blood, released yesterday, found that the products nearly tripled the risk of heart attacks and boosted the chances of dying by 30 percent. Based on the findings, the researchers questioned why the FDA allowed additional testing of the products to go forward and why the agency is considering letting yet another study proceed. "It's hard to understand," said Charles Natanson, a senior investigator at the National Institutes of Health who led the analysis. "They already had data that these products could cause heart attacks and evidence that they could kill." An artificial blood substitute that has a long shelf life and does not need refrigeration could save untold lives by providing an alternative to trauma patients in emergencies, especially in rural areas and in combat settings. But attempts to develop such products have been marred by repeated failures and fraught with controversy, in part because some products have been studied under rules allowing researchers to administer them without obtaining consent from individual patients. After the Washington-based consumer group Public Citizen sued the FDA to gain access to data submitted to the agency, Natanson and colleagues at NIH and Public Citizen pooled data from studies conducted between 1998 and 2007.
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