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Vinyl chloride entered the spotlight after the Feb. 3 Ohio train derailment. But the hazardous substance has been around for decades and is everywhere – from buildings and vehicle upholstery to children's toys and kitchen supplies – and factories have been emitting the EPA-designated toxic chemical into the air for years. The train that derailed had the manmade and volatile compound on board, prompting temporary evacuations. But the derailment isn't the first time vinyl chloride has alarmed experts. Experts say that the volatile compound, "used almost exclusively by the plastics industry," has "leached into groundwater from spills, landfills, and industrial sources," and that people who live around plastic manufacturing facilities "may be exposed to vinyl chloride by inhalation of contaminated air." According to the EPA's Toxics Release Inventory (TRI), which "tracks the management of certain toxic chemicals that may pose a threat to human health and the environment," there are 38 TRI facilities in 15 states – mostly around the Gulf of Mexico and the eastern U.S. – that use vinyl chloride, emitting about half a million pounds of the substance every year. The problem begins at vinyl chloride's origins. It's generated from ethane, which is obtained through fracking natural gas. The U.S. Energy Information Administration said ethane production hit a monthly record last year of more than 2.4 million barrels per day. The global PVC market is expected to become a $56.1 billion industry within the next 3 years. 

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Roughly 110,000 Americans died from a drug overdose between February 2021 and February 2022. That figure is part of a larger troubling trend. Life expectancy in the U.S. fell in 2020 and again in 2021, after decades of progress. Deaths linked to alcohol, drugs, and suicide are a major part of that change. Overdoses, suicides and other "deaths of despair" ... have been climbing since the 1990s and may have accelerated in recent years. Losing a job, recovering from an accident or illness, and experiencing divorce or financial difficulties may trigger desperation. People may use drugs and alcohol to ease these uncomfortable mental states. Scientific evidence shows that one common denominator in this cycle of stress, anxiety, depression and substance abuse is physical pain. The relationship between despair and pain is multifaceted. As most people know from personal experience, physical pain increases psychological distress and anxiety. The reverse relationship is also possible: psychological distress can cause physical pain. When someone is in a negative mood, researchers have found, the brain areas that play a role in physical pain also engage. The opioid epidemic may be the most prominent example of how physical pain and despair interact. The misuse of painkillers, especially opioids, generates changes in the brain that trigger higher pain sensitivity, as well as greater tolerance of and addiction to these drugs. As a result, people are more likely to overdose on these medications.

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When Covid-19 struck ... four organizations took on roles often played by governments – but without the accountability of governments. While nations were still debating the seriousness of the pandemic, the groups identified potential vaccine makers and targeted investments in the development of tests, treatments and shots. And they used their clout with the World Health Organization to help create an ambitious worldwide distribution plan. The largest and most powerful was the Bill & Melinda Gates Foundation, one of the largest philanthropies in the world. Then there was Gavi, the global vaccine organization that Gates helped to found to inoculate people in low-income nations, and the Wellcome Trust, a British research foundation with a multibillion dollar endowment that had worked with the Gates Foundation in previous years. Finally, there was the Coalition for Epidemic Preparedness Innovations, or CEPI, the international vaccine research and development group that Gates and Wellcome both helped to create in 2017. The organizations spent at least $8.3 million lobbying the U.S. and E.U., according to an analysis of lobbying disclosures. Now, critics are raising significant questions about the equity and effectiveness of the group's response to the pandemic – and the serious limitations of outsourcing the pandemic response to unelected, privately-funded groups.

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Johnson & Johnson must pay a $2.1 billion award to women who claimed its baby powder was contaminated with cancer-causing asbestos, after the U.S. Supreme Court left intact the largest verdict in the almost decadelong litigation over the iconic product. The top U.S. court without comment on Tuesday refused to consider J&J's objections to a St. Louis jury's 2018 finding that its talc-based powder helped cause ovarian cancer in 20 women. J&J prepared for the appeal's denial by announcing in February it was setting aside almost $4 billion to cover the St. Louis verdict. The company still faces more than 25,000 lawsuits blaming baby powder for causing cancers. J&J pulled the product off U.S. and Canadian shelves last year. Jurors in the St. Louis case awarded each woman $25 million in compensatory damages. The panel then added more than $4 billion in punitive damages, making the award the sixth-largest in U.S. legal history. The original verdict sparked a significant drop in J&J's shares. J&J has lost other cases at trial, with juries across the U.S. ordering it to pay hundreds of millions of dollars. Judges slashed some of those awards while others have been thrown out or are on appeal. J&J has won cases as well. Asbestos, which is often found where talc is mined, is a recognized carcinogen. The women also contended that J&J showed years of deceit about its product and disregard for the health of its customers and argued that warranted the punitive damage award.

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Nearly 40% of US Marines are declining Covid-19 vaccinations, according to data provided to CNN on Friday by the service, the first branch to disclose service-wide numbers on acceptance and declination. As of Thursday, approximately 75,500 Marines have received vaccines, including fully vaccinated and partially vaccinated service men and women. About 48,000 Marines have chosen not to receive vaccines, for a declination rate of 38.9%. The declination rate at Camp Lejeune in North Carolina, one of the prominent Marine Corps bases, was far higher, at 57%, according to another set of data. Of 26,400 Marines who have been offered vaccinations, 15,100 have chosen not to receive them. The military cannot make the vaccines mandatory now because they have only emergency use authorizations from the Food and Drug Administration, meaning service members who are required to receive a series of other vaccinations have the option of declining shots to protect against Covid-19. Officials say most of the vaccine hesitancy stems from concerns about the speed at which the vaccines were developed and fears over long-term effects. The Defense Department has approximately 2.2 million service members operating around the globe.

Note: For more along these lines, see concise summaries of deeply revealing news articles on coronavirus vaccines from reliable major media sources.

Sperm counts have been dropping; infant boys are developing more genital abnormalities; more girls are experiencing early puberty; and adult women appear to be suffering declining egg quality and more miscarriages. It's not just humans. Scientists report genital anomalies in a range of species, including unusually small penises in alligators, otters and minks. In some areas, significant numbers of fish, frogs and turtles have exhibited both male and female organs. Experts say the problem is a class of chemicals called endocrine disruptors, which mimic the body's hormones and thus fool our cells. This is a particular problem for fetuses as they sexually differentiate early in pregnancy. Endocrine disruptors can wreak reproductive havoc. These endocrine disruptors are everywhere: plastics, shampoos, cosmetics, cushions, pesticides, canned foods and A.T.M. receipts. They often aren't on labels and can be difficult to avoid. Chemical companies ... lobby against even safety testing of endocrine disruptors, so that we have little idea if products we use each day are damaging our bodies or our children. Still, the Endocrine Society, the Pediatric Endocrine Society, the President's Cancer Panel and the World Health Organization have all warned about endocrine disruptors, and Europe and Canada have moved to regulate them. But in the United States, Congress and the Trump administration seemed to listen more to industry lobbyists than to independent scientists.

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Current COVID-19 lockdowns protect low-risk college students and young professional bankers, attorneys, journalists, scientists and others who can work from home, while older high-risk working-class people are risking their lives building the population immunity that will eventually protect us all. While mortality is inevitable during a pandemic, the COVID-19 lockdown strategy has led to more than 220,000 deaths, with the urban working class carrying the heaviest burden. Many older workers have been forced to accept high mortality risk or increased poverty, or both. While the current lockdowns are less strict than in March, the lockdown and contact tracing strategy is the worst assault on the working class since segregation and the Vietnam War. Lockdown policies have closed schools, businesses and churches, while not enforcing strict protocols to protect high-risk nursing home residents. Denying in-person teaching to students is harmful to their education and physical and mental health, with working-class children hardest hit. Online schooling puts a disproportional burden on our children, despite their own minimal risk. For ages 1 to 15, Sweden kept day care and schools open throughout the height of the pandemic, and among the 1.8 million children of that age, there were zero COVID-19 deaths without masks used or physical distancing. Neither was there any excess risk for in-person teachers compared with the average of other professions.

Note: The above article was written by three doctors, one from Stanford, one from Harvard, and one from the UK's Oxford. Explore an abundance of good information questioning the official story of COVID. Explore a summary of alternative views on the coronavirus. Explore a revealing article questioning the origin and causes of the coronavirus. For more along these lines, see concise summaries of deeply revealing news articles on the coronavirus from reliable major media sources.

A leading epidemiologist says "thousands of people" will be quarantined in isolation facilities for months - and possibly years - into the future. University of Otago professor of public health Michael Baker's appearance on Newshub Nation on Saturday comes after multiple cases of people breaking out of their facilities. Prof Baker says ... we need to be prepared for a "long-term risk management challenge". "Mistakes happen, and we have to learn from them and improve our systems so we don't repeat those errors," he [said]. "We're going to have thousands of people sitting in these facilities, quarantined in isolation facilities for months, maybe years ahead." The latest escapee, a person in their 60s, broke the window of the Waipuna Hotel in Auckland on Friday and climbed out of the building. Their escape is the fourth since last Saturday, when a woman scaled two fences to escape from Auckland's Pullman Hotel. On Tuesday, a 32-year-old man snuck through a gap in the Stamford Plaza fencing and visited an inner-city supermarket. Prof Baker says we need to look at why these people feel the need to escape from the isolation facilities. ACT leader David Seymour said the Government needs to start profiling travelers based on their risk of absconding. "The vast majority of people entering New Zealand will pose absolutely no risk of absconding from managed isolation and quarantine facilities," he said in a statement. "But a tiny minority will be a risk. The Government should ... place them under tighter security."

Note: Baker likely is not referring to individuals being detained for years, but to these policies continuing for years. A second MSN article includes a video describing how police are now guarding the quarantine facilities in New Zealand, which is being called "managed isolation." The "managed isolation" aka quarantine policy started in April. As this article states, "every person arriving in New Zealand will have to go into compulsory quarantine as a measure to try and combat Covid-19." For more, see summaries of revealing news articles on the coronavirus from major media sources.

Doctors have used ultrasound to successfully treat prostate cancer in a new study promising a new alternative to surgery. Prostate is the second most deadly type of cancer in men, with lung cancer the only variant to claim more lives. Treatment is challenging because surgery and radiation can leave men incontinent or impotent. However, a pioneering new technique avoids the risks by using a rod-shaped device inserted into the urethra while guided by magnetic resonance to administer precise bursts of ultrasound. The sound waves heat and destroy the tumour, leaving surrounding areas unharmed. The new study was presented at the annual meeting of the Radiological Society of North America and involved 115 men with localised prostate cancer. After treatment with ultrasound, clinically significant cancer was eliminated in 80 per cent of the group, with 65 per cent having no signs of cancer after one year. Most of the men also saw reduced blood-antigen markers for prostate cancer, and overall no bowel complications were reported. Study co-author Steven Raman, professor of radiology and urology at the University of California at Los Angeles, said: “It’s an outpatient procedure with minimal recovery time. “We saw very good results in the patients, with a dramatic reduction of over 90 per cent in prostate volume and low rates of impotence with almost no incontinence.” The process, called Tulsa-Pro, has been approved for clinical use in Europe.

Note: Why isn't this exciting new development approved or even reported in the US? And learn about a man who developed a similar treatment almost a century ago only to have it quashed by the medical establishment.

Four African countries have reported new cases of polio linked to the oral vaccine, as global health numbers show there are now more children being paralyzed by viruses originating in vaccines than in the wild. In a report late last week, the World Health Organization and partners noted nine new polio cases caused by the vaccine in Nigeria, Congo, Central African Republic and Angola. Seven countries elsewhere in Africa have similar outbreaks and cases have been reported in Asia. Of the two countries where polio remains endemic, Afghanistan and Pakistan, vaccine-linked cases have been identified in Pakistan. In rare cases, the live virus in oral polio vaccine can mutate into a form capable of sparking new outbreaks. All the current vaccine-derived polio cases have been sparked by a Type 2 virus contained in the vaccine. Type 2 wild virus was eliminated years ago. WHO and partners have long relied on oral polio vaccines because they are cheap and can be easily administered. Western countries use a more expensive injectable polio vaccine that contains an inactivated virus incapable of causing polio. The Independent Monitoring Board, a group set up by WHO to assess polio eradication, warned in a report this month that vaccine-derived polio virus is "spreading uncontrolled in West Africa." The group said officials were already "failing badly" to meet a recently approved polio goal of stopping all vaccine-derived outbreaks within 120 days of detection.

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America’s agricultural landscape is now 48 times more toxic to honeybees, and likely other insects, than it was 25 years ago, almost entirely due to widespread use of so-called neonicotinoid pesticides, according to a new study published today in the journal PLOS One. This enormous rise in toxicity matches the sharp declines in bees, butterflies, and other pollinators as well as birds, says co-author Kendra Klein. “This is the second Silent Spring. Neonics are like a new DDT, except they are a thousand times more toxic to bees than DDT was,” Klein says. Using a new tool that measures toxicity to honey bees, the length of time a pesticide remains toxic, and the amount used in a year, Klein and researchers from three other institutions determined that the new generation of pesticides has made agriculture far more toxic to insects. Honey bees are used as a proxy for all insects. The study found that neonics accounted for 92 percent of this increased toxicity. Neonics are not only incredibly toxic to honeybees, they can remain toxic for more than 1,000 days in the environment, said Klein. Some scientists have been warning that there is an “insect apocalypse” underway. A global analysis of 452 species in 2014 estimated that insect abundance had declined 45 percent over 40 years. Not only do bees, butterflies, and other insects pollinate one-third of all food crops, declining insect numbers can also have catastrophic ecological repercussions.

Note: For more along these lines, see concise summaries of deeply revealing news articles on food system corruption from reliable major media sources.

Scientists have long found a possible link between anticholinergic drugs and an increased risk of dementia. A study published in the journal JAMA Internal Medicine on Monday suggests that the link is strongest for certain classes of anticholinergic drugs - particularly antidepressants such as paroxetine or amitriptyline, bladder antimuscarinics such as oxybutynin or tolterodine, antipsychotics such as chlorpromazine or olanzapine and antiepileptic drugs such as oxcarbazepine or carbamazepine. Researchers wrote in the study that "there was nearly a 50% increased odds of dementia" associated with a total anticholinergic exposure of more than 1,095 daily doses within a 10-year period, which is equivalent to an older adult taking a strong anticholinergic medication daily for at least three years, compared with no exposure. The researchers found only an association between anticholinergic drugs and dementia risk, not a causal relationship. "However, if this association is causal, the population-attributable fractions indicate that around 10% of dementia diagnoses are attributable to anticholinergic drug exposure, which would equate, for example, to around 20,000 of the 209,600 new cases of dementia per year in the United Kingdom," the researchers wrote in the study. It has been well known that anticholinergic agents and confusion or memory issues are linked, but the new study investigated this association over a long period of time, said Dr. Douglas Scharre ... at the Ohio State University Wexner Medical Center.

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In 1986, the Soviet minister of hydrometeorology, Yuri Izrael, had a regrettable decision to make. It was his job to track radioactivity blowing from the smoking Chernobyl reactor in the hours after the 26 April explosion and deal with it. If the slow-moving mass of radioactive clouds reached Moscow, where a spring storm front was piling up, millions could be harmed. Soviet air force pilots ... made the easy one-hour flight to Chernobyl, where the reactor burned. When they caught up with a cloud, they shot jets of silver iodide into it. Wherever pilots shot silver iodide, rain fell, along with a toxic brew of a dozen radioactive elements. No one told the Belarusians that the southern half of the republic had been sacrificed to protect Russian cities. The Chernobyl explosions issued 45m curies of radioactive iodine into the atmosphere. Emissions from Soviet and US bomb tests amounted to 20bn curies of radioactive iodine, 500 times more. When the Chernobyl accident occurred, experts in radiation medicine called for a long-term epidemiological study on Chernobyl-exposed people. That study never occurred. Fortunately, Chernobyl health records are now available to the public. They show that people living in the radioactive traces fell ill from cancers, respiratory illness, anaemia, auto-immune disorders, birth defects, and fertility problems two to three times more frequently in the years after the accident than before.

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U.S. Senator Bernie Sanders plans to send a letter to Catalyst Pharmaceuticals on Monday asking it to justify its decision to charge $375,000 annually for a medication that for years has been available to patients for free. The drug, Firdapse, is used to treat Lambert-Eaton Myasthenic Syndrome (LEMS), a rare neuromuscular disorder. The disorder affects about one in 100,000 people in the United States. The government is intensifying its scrutiny of the pharmaceutical industry and rising prescription drug prices. Both the Democratic-led U.S. House of Representatives and the Senate, controlled by Republicans, have begun holding hearings this year on the rising costs of medicines. In the letter dated Feb. 4, Sanders asked Catalyst to lay out the financial and non-financial factors that led the company to set the list price at $375,000, and say how many patients would suffer or die as a result of the price and how much it was paying to purchase or produce the drug. For years, patients have been able to get Firdapse for free ... through a U.S. Food and Drug Administration (FDA) program called "compassionate use." The program allows patients with rare diseases and conditions access to experimental drugs outside of a clinical trial when there is no viable alternative. Florida-based Catalyst received FDA approval of Firdapse in November, along with exclusive rights to market the medication for several years. In December, Catalyst announced it would price Firdapse at $375,000 a year.

Note: Read how a major drug price increase nearly bankrupted the city of Rockford, Illinois. For more along these lines, see concise summaries of deeply revealing Big Pharma corruption news articles from reliable major media sources.

Social isolation is a growing epidemic — one that’s increasingly recognized as having dire physical, mental and emotional consequences. Since the 1980s, the percentage of American adults who say they’re lonely has doubled from 20 percent to 40 percent. About one-third of Americans older than 65 now live alone, and half of those over 85 do. People in poorer health — especially those with mood disorders like anxiety and depression — are more likely to feel lonely. Those without a college education are the least likely to have someone they can talk to about important personal matters. A wave of new research suggests social separation is bad for us. Individuals with less social connection have disrupted sleep patterns, altered immune systems, more inflammation and higher levels of stress hormones. One recent study found that isolation increases the risk of heart disease by 29 percent and stroke by 32 percent. Another analysis that pooled data from 70 studies and 3.4 million people found that socially isolated individuals had a 30 percent higher risk of dying in the next seven years, and that this effect was largest in middle age. Loneliness can accelerate cognitive decline in older adults, and isolated individuals are twice as likely to die prematurely as those with more robust social interactions. These effects start early: Socially isolated children have significantly poorer health 20 years later. All told, loneliness is as important a risk factor for early death as obesity and smoking.

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After three tours in Iraq and Afghanistan, C. J. Hardin wound up hiding from the world. He had tried almost all the accepted treatments for post-traumatic stress disorder. “Nothing worked for me,” said Mr. Hardin. Then, in 2013, he joined a small drug trial testing whether PTSD could be treated with MDMA, the illegal party drug better known as Ecstasy. “It changed my life,” he said. “It allowed me to see my trauma without fear or hesitation and finally process things and move forward.” Based on promising results like Mr. Hardin’s, the Food and Drug Administration gave permission Tuesday for large-scale, Phase 3 clinical trials of the drug - a final step before the possible approval of Ecstasy as a prescription drug. The Multidisciplinary Association for Psychedelic Studies, a small nonprofit created in 1985 ... sponsored six Phase 2 studies treating a total of 130 PTSD patients. Two trials ... focused on treating combat veterans, sexual assault victims, and police and firefighters with PTSD who had not responded to traditional prescription drugs or psychotherapy. Patients had, on average, struggled with symptoms for 17 years. After three doses of MDMA administered under a psychiatrist’s guidance, the patients reported a 56 percent decrease of severity of symptoms on average, one study found. By the end of the study, two-thirds no longer met the criteria for having PTSD. Follow-up examinations found that improvements lasted more than a year after therapy.

Note: Read more about how MDMA has been found effective for treating PTSD in a therapeutic context. This FDA approval to begin Phase 3 clinical trials of MDMA suggests that the healing potentials of mind-altering drugs are gaining mainstream scientific credibility.

The American Heart Association and the American College of Cardiology released new guidelines for prescribing cholesterol-lowering medicines. The big winners are expected to be the drug makers that sell statins, since other types of pills were not recommended. Of the 15 panelists that authored these new guidelines, six reported having recent or current ties to drugmakers that already sell or are developing cholesterol medications. And among the half dozen who disclosed these relationships was one of the two panel co-chairs, which contradicts an Institute of Medicine suggestion about managing conflicts and leadership roles on such panels. To be specific, the Institute of Medicine wrote that, “whenever possible, guideline development group members should not have conflicts of interest ... and the chair or co-chairs should not be a person(s) with conflicts of interest.” The Institute of Medicine also wrote that members with conflicts should not represent a majority (here is the IOM report). “One of the reasons the IOM recently recommended eliminating rather than ‘managing’ financial conflicts of interest in guideline development groups is because of concerns about implicit bias,” says Lisa Cosgrove ... at the University of Massachusetts. “When individuals have commercial ties they are vulnerable to developing subtle, but sometimes powerful, pro-industry ways of thinking. Transparency ... can actually worsen the problem, because some people think simply disclosing a tie relieves any moral concern.”

Note: For lots more on this, see an informative article titled "The Statin Mafia Censors Pharmaceutical Harm." For more along these lines, see concise summaries of deeply revealing news articles on pharmaceutical industry corruption from reliable major media sources.

Professor John Lorber ... was not jesting totally when he addressed a conference of pediatricians with a paper entitled "Is your brain really necessary?" "There's a young student at this university," says Lorber, "who has an IQ of 126, has gained a first-class honors degree in mathematics, and is socially completely normal. And yet the boy has virtually no brain." The student's physician at the university noticed that the youth had a slightly larger than normal head, and so referred him to Lorber, simply out of interest. "When we did a brain scan on him," Lorber recalls, "we saw that instead of the normal 4.5-centimeter thickness of brain tissue between the ventricles and the cortical surface, there was just a thin layer of mantle measuring a millimeter or so. His cranium is filled mainly with cerebrospinal fluid." Startling as it may seem, this case is nothing new to the medical world. A substantial proportion of patients appear to escape functional impairment in spite of grossly abnormal brain structure. Lorber concludes from these observations that "there must be a tremendous amount of redundancy or spare capacity in the brain, just as there is with kidney and liver." He also contends that "the cortex probably is responsible for a great deal less than most people imagine. For hundreds of years neurologists have assumed that all that is dear to them is performed by the cortex, but it may well be that the deep structures in the brain carry out many of the functions assumed to be the sole province of the cortex."

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Did you ever feel your own shoulders relax when you saw a friend receive a shoulder massage? For those of you who said "yes," congratulations, your brain is using its power to create a "placebo effect." For those who said "no," you're not alone, but thankfully, the brain is trainable. Since the 1800s, the word placebo has been used to refer to a fake treatment, meaning one that does not contain any active, physical substance. Today, placebos play a crucial role in medical studies in which some participants are given the treatment containing the active ingredients of the medicine, and others are given a placebo. These types of studies help tell researchers which medicines are effective, and how effective they are. Surprisingly, however, in some areas of medicine, placebos themselves provide patients with clinical improvement. Research suggests that the placebo effect is caused by positive expectations, the provider-patient relationship and the rituals around receiving medical care. Depression, pain, fatigue, allergies, irritable bowel syndrome, Parkinson's disease and even osteoarthritis of the knee are just a few of the conditions that respond positively to placebos. In addition to the ever-increasing body of evidence surrounding their effectiveness, placebos offer multiple benefits. They have no side effects. They are cheap. They are not addictive. They provide hope when there might not be a specific chemically active treatment available. They mobilize a person's own ability to heal through multiple pathways.

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The reminders of pandemic-driven suffering among students in Clark County, Nev., have come in droves. Since schools shut their doors in March, an early-warning system that monitors students' mental health episodes has sent more than 3,100 alerts to district officials, raising alarms about suicidal thoughts, possible self-harm or cries for care. By December, 18 students had taken their own lives. The spate of student suicides in and around Las Vegas has pushed the Clark County district, the nation's fifth largest, toward bringing students back as quickly as possible. This month, the school board gave the green light to phase in the return of some elementary school grades and groups of struggling students. Over the summer ... Dr. Robert R. Redfield, then the C.D.C. director, warned that a rise in adolescent suicides would be one of the "substantial public health negative consequences" of school closings. Mental health advocacy groups warned that the student demographics at the most risk for mental health declines before the pandemic – such as Black children and L.G.B.T.Q. students – were among those most marginalized by the school closures. But given the politically charged atmosphere this summer, many of those warnings were dismissed as scare tactics. Parents of students who have taken their lives say connecting suicide to school closings became almost taboo.

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