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A man from London has become the second person in the world to be cured of HIV, doctors say. Adam Castillejo is still free of the virus more than 30 months after stopping anti-retroviral therapy. He was not cured by the HIV drugs, however, but by a stem-cell treatment he received for a cancer he also had, the Lancet HIV journal reports. The donors of those stem cells have an uncommon gene that gives them, and now Mr Castillejo, protection against HIV. In 2011, Timothy Brown, the "Berlin Patient" became the first person reported as cured of HIV, three and half years after having similar treatment. Stem-cell transplants appear to stop the virus being able to replicate inside the body by replacing the patient's own immune cells with donor ones that resist HIV infection. Adam Castillejo - the now 40-year-old "London Patient" who has decided to go public with his identity - has no detectable active HIV infection in his blood, semen or tissues, his doctors say. It is now a year after they first announced he was clear of the virus and he still remains free of HIV. Lead researcher Prof Ravindra Kumar Gupta, from the University of Cambridge, told BBC News: "This represents HIV cure with almost certainty. "We have now had two and a half years with anti-retroviral-free remission. "Our findings show that the success of stem-cell transplantation as a cure for HIV, first reported nine years ago in the Berlin Patient, can be replicated."

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Vice-premier Sun Chunlan, one of the most senior government officials to visit the centre of the coronavirus outbreak [was] heckled by residents who yelled “fake, fake, everything is fake” as she inspected the work of a neighbourhood committee charged with taking care of quarantined residents. Videos posted online showed Sun and a delegation walking along the grounds while residents appeared to shout from their apartment windows, “fake, fake,” “it’s all fake,” as well as “we protest”. Since 12 February, all residential compounds in Wuhan have been put under lockdown, barring most residents from leaving their homes. In an unusual turn of events, on Friday various Chinese state media outlets reported the videos showing public discontent. Such videos are frequently censored. Yet, the People’s Daily posted a video subtitled in English showing one person shouting “fake, fake,” which has since been removed. A government-affiliated account on WeChat ... said in an essay posted on Thursday that all the facts of the incident were “basically true”. According to state broadcaster CCTV, Sun held a meeting immediately after the incident to deal with the complaints. Staff have been dispatched to visit the residents one by one. Observers say state media may be trying to co-opt discussion of the videos, which circulated widely online, and provide their own narrative of events. Elsewhere in China, schools in provinces reporting no new cases for a number of days, started to set their opening dates in a sign of the country returning to normal. Wuhan reported 126 new coronavirus cases on Thursday but the wider province of Hubei excluding the capital recorded none for the first time during the outbreak.

Note: Remember all of the privacy and freedoms given up after 9/11? How many of those have been given back? Learn more about the serious risk of the Coronavirus increasing the surveillance state in this excellent article. For more along these lines, see concise summaries of deeply revealing news articles on government corruption and the disappearance of privacy from reliable major media sources.

In a direct challenge to California regulators and Bay Area environmentalists, the Trump administration Thursday ordered companies to ignore state requirements that businesses warn customers if their products contain glyphosate, a weed killer that has been linked to cancer. The decision flies in the face of three California court rulings against Monsanto, which markets the chemical as Roundup. The agricultural giant faces more than 13,000 suits nationwide by users of Roundup, the world’s best-selling herbicide. The U.S. Environmental Protection Agency announced it would no longer approve labels saying glyphosate is known to cause cancer. The state requires companies to warn customers about chemicals known to cause cancer under the Safe Drinking Water and Toxic Enforcement Act. Glyphosate was classified as a probable human carcinogen in 2015 by the International Agency for Research on Cancer, which is part of the World Health Organization. Lawyers for sick clients who were awarded tens of millions of dollars after suing Monsanto introduced evidence that glyphosate can cause genetic damage that leads to non-Hodgkin’s lymphoma. They claimed Monsanto ignored that information and published information “ghost written” by staffers denying the toxicity of the chemical. Superior Court Judge Winifred Smith said there was clear evidence that Monsanto, after learning of the dangers, “made efforts to impede, discourage or distort scientific inquiry” by regulators.

Note: For more along these lines, see concise summaries of deeply revealing news articles on corporate corruption from reliable major media sources.

In May 2008, as the opioid epidemic was raging in America, a representative of the nation’s largest manufacturer of opioid pain pills sent an email to a client at a wholesale drug distributor in Ohio. Victor Borelli, a national account manager for Mallinckrodt, told Steve Cochrane, the vice president of sales for KeySource Medical, to check his inventories and “[i]f you are low, order more. If you are okay, order a little more, Capesce?” Then Borelli joked, “destroy this email ... Is that really possible? Oh Well...” Those email excerpts are quoted in a 144-page plaintiffs’ filing along with thousands of pages of documents unsealed by a judge’s order Friday in a landmark case in Cleveland against many of the largest companies in the drug industry. A Drug Enforcement Administration database released earlier in the week revealed that the companies had inundated the nation with 76 billion oxycodone and hydrocodone pills from 2006 through 2012. Nearly 2,000 cities, counties and towns are alleging that the companies knowingly flooded their communities with opioids, fueling an epidemic that has killed more than 200,000. The filing by plaintiffs depict some drug company employees as driven by profits and undeterred by the knowledge that their products were wreaking havoc across the country. Plaintiffs in the case argue that the actions of some of America’s biggest and best-known companies - including Mallinckrodt, Cardinal Health, McKesson, Walgreens, CVS, Walmart and Purdue Pharma - amounted to a civil racketeering enterprise.

Note: For more along these lines, see concise summaries of deeply revealing news articles on pharmaceutical industry corruption from reliable major media sources.

The Centers for Disease Control and Prevention is conflating the results of two different types of coronavirus tests, distorting several important metrics and providing the country with an inaccurate picture of the state of the pandemic. We’ve learned that the CDC is making, at best, a debilitating mistake: combining test results that diagnose current coronavirus infections with test results that measure whether someone has ever had the virus. The agency confirmed to The Atlantic on Wednesday that it is mixing the results of viral and antibody tests, even though the two tests reveal different information and are used for different reasons. This is not merely a technical error. The upshot is that the government’s disease-fighting agency is overstating the country’s ability to test people who are sick with COVID-19. States have set quantitative guidelines for reopening their economies based on these flawed data points. Several states - including Pennsylvania, the site of one of the country’s largest outbreaks, as well as Texas, Georgia, and Vermont - are blending the data in the same way. Virginia likewise mixed viral and antibody test results until last week, but it reversed course and the governor apologized for the practice. These results damage the public’s ability to understand what is happening in any one state. On a national scale, they call the strength of America’s response to the coronavirus into question. The number of tests conducted nationwide each day has more than doubled in the past month. At the same time, the portion of tests coming back positive has plummeted.

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Former patients of a retired Indianapolis fertility doctor expressed anger that he avoided jail time Thursday for lying about using his own sperm to impregnate as many as dozens of women after telling them the donors were anonymous. Dr. Donald Cline was given a one-year suspended sentence after pleading guilty to two counts of obstruction of justice. No other charges were filed ... because Indiana law doesn't specifically prohibit fertility doctors from using their own sperm. The charges stemmed from two confirmed cases of paternity. Matt White and his mother, Liz White, said Cline deserved far greater punishment. He said DNA tests showed that Cline was his biological father even though Cline told his mother decades ago that he used anonymous sperm donations. "There's dozens of us," said Matt White. Some of the now-adult children of Cline's former patients filed a complaint with the Indiana Attorney General's Office in 2014, after they became suspicious while scouring online records to find biological relatives. Paternity tests performed the Marion County prosecutor's office determined Cline was likely the biological father of at least two of his patients' children. Cline, who retired in 2009, initially denied the allegations when he wrote to investigators, saying the women who filed the complaints were trying to slander him. On Thursday, he acknowledged that he had lied. Matt White said private DNA tests have identified 23 people as Cline's biological children with mothers who were his patients.

Note: See a list of powerful articles revealing egregious and rampant sexual abuse by doctors around the US. For more along these lines, see concise summaries of deeply revealing news articles on sexual abuse scandals and health.

Researchers taught male mice to fear the smell of cherry blossoms by associating the scent with mild foot shocks. Two weeks later, they bred with females. The resulting pups were raised to adulthood having never been exposed to the smell. Yet when the critters caught a whiff of it for the first time, they suddenly became anxious and fearful. They were even born with more cherry-blossom-detecting neurons in their noses and more brain space devoted to cherry-blossom-smelling. The memory transmission extended out another generation when these male mice bred. Neuroscientists at Emory University found that genetic markers, thought to be wiped clean before birth, were used to transmit a single traumatic experience across generations, leaving behind traces in the behavior and anatomy of future pups. The study, published ... in the journal Nature Neuroscience, adds to a growing pile of evidence suggesting that characteristics outside of the strict genetic code may also be acquired from our parents through epigenetic inheritance. Epigenetics studies how molecules act as DNA markers that influence how the genome is read. We pick up these epigenetic markers during our lives and in various locations on our body as we develop and interact with our environment. The researchers also artificially inseminated females using the sperm from the original fear-conditioned mice. The results were the same, suggesting epigenetic inheritance rather than environment.

Note: The emerging field of epigenetics implies that lifestyle and environment influence the expression of DNA. For more along these lines, see concise summaries of deeply revealing news articles on health from reliable major media sources.

Patients prescribed drugs for movement disorders - including restless leg syndrome (RLS) - say doctors did not warn them about serious side effects that led them to seek out risky sexual behaviour. Twenty women have told the BBC that the drugs - given to them for RLS, which causes an irresistible urge to move - ruined their lives. A report by drugs firm GSK - seen by the BBC - shows it learned in 2003 of a link between the medicines, known as dopamine agonist drugs, and what it described as "deviant" sexual behaviour. It cited a case of a man who had sexually assaulted a child while taking the drug for Parkinson's. Some of the women who described being drawn to risky sexual behaviour told us they had no idea of what was causing it. Others said they felt compelled to gamble or shop with no history of such activities. Impulsive behaviours, including gambling and increased sex drive, have long been listed as side effects in medicine leaflets for dopamine agonist drugs - and are thought to affect between 6% to 17% of RLS patients taking them, according to health guidance body NICE. The cases of what the GSK report from 2003 described as "deviant behaviour" involved two men who were prescribed Ropinirole for Parkinson's disease. In one, a 63-year-old-man sexually assaulted a seven-year-old girl, leading to a custodial sentence. In the second case, a 45-year-old man carried out "uncontrolled acts of exhibitionism and indecent behaviour".

Note: For more along these lines, read our concise summaries of news articles on Big Pharma corruption.

Health care is so expensive that 31 million U.S. adults, or 12%, had to borrow a total of $74 billion last year to obtain medical care, new data shows. That includes people with health insurance, making such numbers even more troubling. Almost one-third of the more than 3,500 people surveyed by Gallup and West Health, a group of nonprofit health care organizations, said they're "very concerned" that a major health event would lead to medical debt despite most of them having some form of health care coverage. To avoid taking on debt, families sometimes make tradeoffs, such as purchasing fewer groceries or not paying rent in order to get the care they need. Nearly one in five adults between the ages of 18 and 28 reported borrowing money to pay for health care, according to the survey. Only 9% of Americans between 50 and 64 and 2% of those 65 or older reported having to borrow money to obtain needed medical care. "There are a lot of disparities in terms of who borrows," [Tim Lash, president of West Health] said. That's in part because Medicare, which is available to people who are 65 or older, provides enrollees with relatively comprehensive coverage. As of mid-2024, U.S. residents owed at least $220 billion in medical debt, according to data from the American Hospital Association. Health care bills have for years been a leading cause of personal bankruptcies.

Note: Two-thirds of personal bankruptcies in the US are caused by illnesses and medical bills. For more along these lines, read our concise summaries of news articles on health and financial inequality.

Antidepressants are frequently prescribed to people with dementia for symptoms like anxiety, depression, aggressiveness and sleeplessness. But a specific class of antidepressant medications - selective serotonin reuptake inhibitors (SSRIs) - actually might speed up brain decline among some dementia patients, a new Swedish study suggests. Heavier doses of certain SSRIs are tied to a higher risk for severe dementia, researchers reported in a new study ... in the journal BMC Medicine. The SSRI drug escitalopram was associated with the fastest cognitive decline, followed by citalopram and sertraline. For the study, researchers tracked the brain health of more than 18,700 patients enlisted in the Swedish Registry for Cognitive/Dementia Disorders between May 2007 and Oct. 2018. The patients' average age was 78. During an average follow-up of more than four years, about 23% of patients received a new prescription for an antidepressant, researchers said. SSRIs were the most commonly prescribed antidepressant, amounting to 65% of all those prescriptions, the study says. "Higher dispensed doses of SSRIs were associated with higher risk for severe dementia, fractures, and all-cause mortality," the researchers concluded. "These findings highlight the significance of careful and regular monitoring to assess the risks and benefits of different antidepressants use in patients with dementia."

Note: For more along these lines, read our concise summaries of news articles on Big Pharma corruption.

Pesticide company efforts to push through laws that could block litigation against them is igniting battles in several US farm states. Laws have been introduced in at least eight states so far and drafts are circulating in more than 20 states, backed by a deluge of advertising supporting the measures. The fight is particularly fierce now in Iowa, where opponents call the pesticide-backed proposed law the "Cancer Gag Act", due to high levels of cancer in Iowa that many fear are linked to the state's large agricultural use of pesticides. Iowa has the second-highest rate of new cancer cases in the United States and the fastest growing rate. The bill would bar people from suing pesticide manufacturers for failing to warn them of health risks, as long as the product labels are approved by the Environmental Protection Agency (EPA). Opponents say the legislation will rob farmers and others who use pesticides from holding companies accountable in court if their pesticide products cause disease or injury. "We're very worried. Our farmers feel that if they have injuries or illnesses due to their use of a pesticide they should have access to the courts," said [Iowa Farmers Union president] Aaron Lehman. The actions in the states come alongside a simultaneous push for changes in federal law that would in effect shield companies from lawsuits brought by people claiming they developed cancers or other diseases due to their use of pesticides.

Note: Thousands of farmers and everyday people have filed lawsuits against major corporations for failing to warn consumers about the health risks associated with these chemicals. For more along these lines, read our concise summaries of news articles on toxic chemicals and food system corruption.

A former director at the tobacco giant Philip Morris International (PMI) was handed a role on an influential expert committee advising the UK government on cancer risks. Ruth Dempsey, the ex-director of scientific and regulatory affairs, spent 28 years at PMI before being appointed to the UK Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment (CoC). The committee's role is to provide ministers with independent advice. Yet since taking up the position in February 2020, Dempsey has continued to be paid by PMI for work including authoring a sponsored paper about regulatory strategies for heated tobacco products. She also owns shares in the tobacco giant ... and receives a PMI pension. But her appointment, unreported until now, raises questions about the potential for undue influence and possible access to inside information on policy and regulatory matters that may be valuable to the tobacco industry. PMI has a long history of lobbying and influence campaigns, including pushing against planned crackdowns on vaping. It has also invested heavily in promoting heated tobacco as an alternative to smoking and expects to ship around 140bn heated tobacco units in 2024, a 134% increase on its 59.7bn sales in 2019. Sophie Braznell, who monitors heated tobacco products as part of the University of Bath's Tobacco Control Research Group, said Dempsey's position on the committee risked undermining its work. "In permitting a former senior tobacco employee and consultant for the world's largest tobacco company to join this advisory committee, we jeopardise its objectivity and integrity."

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The tobacco company Philip Morris International has been accused of "manipulating science for profit" through funding research and advocacy work with scientists. Campaigners say that leaked documents from PMI and its Japanese affiliate also reveal plans to target politicians, doctors and the 2020 Tokyo Olympics as part of the multinational's marketing strategy to attract non-smokers to its heated tobacco product, IQOS. A paper from researchers at the Tobacco Control Research Group at the University of Bath said that Philip Morris Japan (PMJ), funded a Kyoto University study into smoking cessation via a third-party research organisation. The researchers said they could find no public record of PMJ's involvement, although a PMI spokesperson said its involvement had been attributed when the results were presented at a scientific conference in Greece in 2021. PMJ paid about Ł20,000 a month to FTI-Innovations, a life sciences consultancy run by a Tokyo University professor, for tasks such as promoting PMI's science and products at academic events. In one internal email, a PMJ employee claimed they had been told "to keep it a secret". Dr Sophie Braznell, one of [the paper's] authors, said: "The manipulation of science for profit harms us all, especially policymakers and consumers. It slows down and undermines public health policies, while encouraging the widespread use of harmful products."

Note: For more along these lines, see concise summaries of deeply revealing news articles on health and science corruption from reliable major media sources.

Research from the Center for International Environmental Law (CIEL) details the widespread burdens that plastic pollution places on US cities and states, and argues that plastic producers may be breaking public-nuisance, product-liability and consumer-protection laws. It comes as cities such as Baltimore have begun to file claims against plastic manufacturers, but the authors write that existing cases "are likely only the beginning, as more states and municipalities grapple with the challenges of accumulating plastic waste and microplastics contamination." Taxpayers foot the bill to clean plastic pollution from streets and waterways, and research shows people could ingest the equivalent of one credit card's worth of plastic per week. From 1950 to 2000, global plastic production soared from 2m tons to 234m tons annually. And over the next 20 years, production more than doubled to 460m tons in 2019. As the public grew concerned about plastic pollution, the industry responded with "sophisticated marketing campaigns" to shift blame from producers to consumers – for instance, by popularizing the term litterbug. Plastic has clogged sewer grates, leading to increased flooding. It has also exposed populations to microplastics. The report outlines different legal theories that could help governments pursue accountability. Nuisance could account for the harms themselves ... and consumer-protection law could be used to combat deceitful marketing practices.

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Nonprofit hospitals have been caught doing some surprising things, given how they are supposed to serve the public good in exchange for being exempt from federal, state and local taxes – exemptions that added up to $28 billion in 2020. Detailed media reports show them hounding poor patients for money, cutting nurse staffing too aggressively and giving preferential treatment to the rich over the poor. Nurses and other workers recently resorted to strikes to improve workplace safety at Kaiser Permanente and the Robert Wood Johnson University Hospital in New Brunswick, N.J. That's not the end of it. Nonprofit executives have embarked on an acquisition spree, assembling huge systems of hospitals and physician practices to raise prices and increase profits. Ample evidence indicates that the growth of these giant systems makes health care less affordable for patients, families and businesses. Calling these hospitals nonprofits can be confusing. It doesn't mean they can't make money. What it means is that they are considered charities by the Internal Revenue Service (as opposed to being owned by investors, like for-profit hospitals). And in return for their tax exemptions, these institutions are supposed to invest the money that would have gone to taxes into their communities by lowering health care costs, providing community health services and free care to those unable to afford it and conducting research.

Note: For more along these lines, see concise summaries of deeply revealing news articles on health and corporate corruption from reliable major media sources.

South Korea is to offer reclusive youths a monthly living allowance of 650,000 won ($490) in order to encourage them out of their homes, as part of a new measure passed by the Ministry of Gender Equality and Family. The measure also offers education, job and health support. The condition is known as "hikikomori", a Japanese term that roughly translated means, "to pull back". The government wants to try to make it easier for those experiencing it to leave the house to go to school, university or work. Included in the programme ... is a monthly allowance for living expenses for people aged between nine and 24 who are experiencing extreme social withdrawal. It also includes an allowance for cultural experiences for teenagers. About 350,000 people between the ages of 19 and 39 in South Korea are considered lonely or isolated – about 3% of that age group – according to the Korea Institute for Health and Social Affairs. Secluded youth are often from disadvantaged backgrounds and 40% began living reclusively while adolescents, according to a government document outlining the measures. The document includes case studies that describe young people using reclusiveness as a way to cope. One young person describes their depression as a result of domestic violence. "When I was 15 years old, domestic violence made me depressed so much that I began to live in seclusion." Another said that they had become a recluse when their family "went bankrupt".

Note: A deeper perspective on this social crisis is how lockdown policies significantly deteriorated youth mental health during the lockdown, as seen in a new University of Cambridge paper. This paper is the first longitudinal study to trace the mental health effects of lockdowns and social isolation on younger children. For more along these lines, see concise summaries of deeply revealing news articles on health from reliable major media sources.

Almost 1.5 million people of working age in Japan are living as social recluses, according to a government survey, with about a fifth of cases attributed to the pressures unleashed by the Covid-19 pandemic. Large numbers of hikikomori said they had begun retreating from mainstream society due to relationship issues and after losing or leaving their jobs. A significant proportion – 20.6% – said their predicament had been triggered by changes in lifestyle imposed during the pandemic. Hikikomori – classed as people who withdraw from society, spending all or almost all of their time isolated at home – account for 2% of people aged 15-62. The cabinet office surveyed 30,000 people between the ages of 10 and 69. The poll found that just over a fifth of respondents aged 15-39 had been socially isolated. More than 20% said they had experienced problems with interpersonal relationships, while just over 18% cited the pandemic. Among people in the 40-64 age range, 44.5% said their behaviour had been triggered by leaving their jobs, followed by 20.6% who cited the pandemic. Japan did not enforce UK-style lockdowns to help contain the spread of the virus, but people were asked to avoid unnecessary outings ... and some employers and universities encouraged teleworking and remote learning. On streets that would normally have been teeming with people there was a dramatic drop in footfall after restaurants, bars and other sectors of the nighttime economy were asked to stop serving alcohol and close early, or face fines.

Note: For more along these lines, see concise summaries of deeply revealing news articles on the coronavirus and health from reliable major media sources.

For the first time, adults with mild to moderate hearing loss in the US will be able to buy over-the-counter hearing aids. Those who are under 18 or who have severe hearing loss will still need a prescription. In July, President Joe Biden signed an executive order meant to promote competition; it encouraged the US Food and Drug Administration allow over-the-counter, prescription-free hearing aids, and the FDA announced the long-awaited rule change in August. The move ushers in options that should be cheaper and possibly even better. Now, instead of getting a prescription and having a custom fitting with a hearing health professional, adults can buy hearing aids directly from a store or online. Some doctors estimate that 90% of the population with hearing loss could benefit from these over-the-counter devices. Experts say the move is a "game-changer." The number of people with hearing loss is substantial. About 1 in 8 people in the US ages 12 and older has hearing loss in both ears. About a quarter of people 65 to 74 have hearing loss. On average, people spend at least $4,000 out of pocket for devices for both ears, according to a 2020 study published in the medical journal JAMA. Prices can vary: Large retailers may offer a pair for about $1,400, but some can cost as much as $6,000 per ear. Until now, five companies have controlled 90% of the global marketplace for hearing aids. That kind of consolidation meant there was little price competition.

Note: Why were these not available over the counter before? Explore a treasure trove of concise summaries of incredibly inspiring news articles which will inspire you to make a difference.

More than eight in 10 kids under the age of 17 have antibodies from a past COVID-19 infection, according to new data from the Centers for Disease Control and Prevention. The analysis shows that as of August, 86% of children between 6 months and 17-years-old have had at least one COVID infection since the pandemic began. That number is an increase from data in April, when the public health agency found 75% of people under the age of 17 had been infected with the virus. "What we have to recognize is this is more of an indication that there's been broad spread of this virus in the pediatric community," said Dr. John Brownstein, an ABC News contributor. "And that, you know, the kids are not sheltered from this virus. And we know that in a small number of cases, there's severe impacts." What the findings don't mean is that 86% of children and adolescents are now protected against COVID reinfection because they've had COVID before. Experts have noted that they don't know exactly how long protection from infection lasts after contracting the virus. "What we should not take away from this data is that that the kids are now immune from infection," Brownstein said. "As we know, immunity wanes, variants evolved to evade prior immunity."

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A new peer-reviewed Danish study finds that a mother's exposure to toxic PFAS "forever chemicals" during early pregnancy can lead to lower sperm count and quality later in her child's life. PFAS – per- and polyfluoroalkyl substances – are known to disrupt hormones and fetal development, and future "reproductive capacity" is largely defined as testicles develop in utero during the first trimester of a pregnancy, said study co-author Sandra Søgaard Tøttenborg. PFAS are a class of about 12,000 chemicals typically used to make thousands of products resistant to water, stains and heat. They are called "forever chemicals" because they accumulate in humans and the environment and do not naturally break down. A growing body of evidence links them to serious health problems such as cancer, birth defects, liver disease, kidney disease and decreased immunity. The study ... examined semen characteristics and reproductive hormones in 864 young Danish men born to women who provided blood samples during their pregnancies' first trimesters between 1996 and 2002. Mothers with higher levels of exposure more frequently raised adult men with lower sperm counts, as well as elevated immotile sperm levels, meaning their sperm did not swim. This exposure also increased the amount of non-progressive sperm – sperm that do not swim straight or swim in circles. Both issues can lead to infertility. The ubiquitous chemicals are estimated to be in 98% of Americans' blood.

Note: For more along these lines, see concise summaries of deeply revealing news articles on health from reliable major media sources.

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