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The coronavirus might be new, but nature long ago gave humans the tools to recognize it, at least on a microscopic scale: antibodies, Y-shaped immune proteins that can latch onto pathogens and block them from infiltrating cells. Millions of years of evolution have honed these proteins into the disease-fighting weapons they are today. But in a span of just months, a combination of human and machine intelligence may have beaten Mother Nature at her own game. Using computational tools, a team of researchers at the University of Washington designed and built from scratch a molecule that, when pitted against the coronavirus in the lab, can attack and sequester it at least as well as an antibody does. This molecule, called a mini-binder for its ability to glom onto the coronavirus, is petite and stable enough to be shipped en masse in a freeze-dried state. Bacteria can also be engineered to churn out these mini-binders, potentially making them not only effective but also cheap and convenient. Eventually, healthy people might be able to self-administer the mini-binders as a nasal spray, and potentially keep any inbound coronavirus particles at bay. Mini-binders are not antibodies, but they thwart the virus in broadly similar ways. The coronavirus enters a cell using a kind of lock-and-key interaction, fitting a protein called a spike – the key – into a molecular lock called ACE-2, which adorns the outsides of certain human cells. Antibodies made by the human immune system can interfere with this process.
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Each weekend, while New York City's East Village packs into sidewalk tables for brunch, activist Carmen Trotta leads a vigil for ending the U.S.-backed war in Yemen in Tompkins Square Park. He only has a few more Saturday mornings before he must report to federal prison, along with fellow activists from Plowshares, the anti-nuclear, Christian pacifist movement. Trotta, Martha Hennessy, Clare Grady, and Patrick O'Neill are due to report to prison within the next few months for activism against a suspected nuclear weapons depot. Trotta and Hennessy ... peacefully broke into the naval base in Brunswick, Georgia – risking their own lives to protest the suspected nuclear arsenal housed within. Armed only with vials of their own blood, hammers, GoPro cameras, spray paint, protest banners, and whistleblower Daniel Ellsberg's book, the activists symbolically attempted to disarm the nuclear weapons located on the Trident submarines at the base. All but one of the activists have quietly been sentenced in their faith-based battle with the U.S. government. The activists were charged with three felonies – conspiracy, destruction of government property, depredation – and misdemeanor trespassing. The sentencing – sending aging activists to federal prisons amid the coronavirus pandemic – fits squarely within the long history of the U.S. government throwing the book at people of conscience who dare to dissent. Trotta got 14 months, Grady was given 12 months and one day, and Hennessy was sentenced to 10 months.
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A great deal of conflicting information has emerged about the immune response that develops in patients who have recovered from Covid-19. The good news is that we are unlikely to be reinfected with Sars-Cov-2 repeatedly until it eventually wipes us all out. Most of the evidence ... shows that the immune response to this is quite typical for an acute viral infection. Initially, the body ramps up high levels of IgG antibodies, but after the infection is cleared, those antibodies drop to a baseline level, which may be below the limit of detection of some serological tests. Most people who recover from Covid-19 have detectable neutralising antibodies months after infection. This suggests that Sars-Cov-2 infection does produce an immune response that is protective, at least for several months. Furthermore, antibodies are not the only important part of the immune system. T-cells are also a key component to the immune response. They come in two flavours: helper T-cells, which coordinate immune responses and facilitate immunological memory, and killer T-cells, which kill infected cells. Previous studies have shown that Sars-Cov-2 infection induces robust T-cell responses. Interestingly, some people who have never had Covid-19 have memory T-cells from prior common-cold coronavirus infections that cross-react with Sars-Cov-2, suggesting that there may be some existing protection in the population. T-cells alone are unlikely to provide complete immune protection, but they are a key contributor to immune memory.
Note: The author of this article, Angela Rasmussen, is a virologist and affiliate of the Georgetown Center for Global Health Science and Security. For more along these lines, see concise summaries of deeply revealing news articles on the coronavirus from reliable major media sources.
While I was in anesthesia residency at the University of Southern California Hospital's Department of Anesthesiology from 2006 to 2009, I learned how to put people under for surgery using an anesthetic called ketamine. Afterwards, as I began work as an anesthesiologist at a hospital, I began hearing interesting things about the anesthetic. Researchers had begun testing it as a treatment for mental health conditions like anxiety, depression, and PTSD – and with encouraging results. It also has psychedelic properties, so people can gain insight into their lives and even have mystical experiences on it. One study found that it reduced symptoms of depression and anxiety in patients with severe depression, both immediately after it was administered and as well as a month down the line. Another found that it even provided relief from chronic pain that lasted for up to two weeks after treatment. In 2014, inspired by findings like these and conversations with psychiatrists who were beginning to incorporate ketamine into their practices, I founded the Ketamine Healing Clinic of Los Angeles. Over time, I've seen people undergo big changes in their lives because of their work with ketamine, including a few who left abusive relationships, grew their businesses, or pursued totally new ventures. Overall ... people typically come out of their infusions with a newfound will to live and increased clarity about their future. Some patients who came in with suicidal thoughts no longer have them at all.
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Special Olympics athlete Chris Nikic crossed the finish line on Saturday to become the first person with Down syndrome to complete an Ironman triathlon. Guiness World Records recognized Nikic's achievement after he finished a 2.4-mile swim, a 112-mile bike ride and a 26.2-marathon run at the Ironman Florida competition in Panama City Beach. "Ironman. Goal set and achieve," said Nikic in a post to Instagram. "Time to set a new and Bigger Goal for 2021." Nikic completed the race in 16 hours 46 minutes and 9 seconds - 14 minutes under the 17-hour cutoff time. Nikic fell off his bike and was attacked by ants at a nutrition stop, but he pushed on to finish the competition. "We are beyond inspired, and your accomplishment is a defining moment in Ironman history that can never be taken away from you," the Ironman Triathlon organization said. Nikic and his father Nik developed the "1 percent better challenge" to stay motivated during training. The idea is to promote Down syndrome awareness while achieving 1% improvement each day, according to Nikic's website. "To Chris, this race was more than just a finish line and celebration of victory," Nik Nikic said. "Ironman has served as his platform to become one step closer to his goal of living a life of inclusion and leadership." Nikic's accomplishment earned him congratulatory messages from celebrities, such as tennis great Billie Jean King and runner Kara Goucher, and people around the world, including 33,000 new followers on social media
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With less than 24 hours' notice, President Emmanuel Macron announced his plan to plunge the French into a second national lockdown for at least a month. And if everything I hear and read about the UK is to be believed, this country is heading in the same direction. While Boris Johnson will be the person announcing that catastrophic decision, the measures are being dictated by a small group of scientists who, in my view, have repeatedly got things terribly wrong. The Scientific Advisory Group for Emergencies (Sage) has made three incorrect assumptions which have had, and continue to have, disastrous consequences for people's lives and the economy. Firstly, Sage assumes that the vast majority of the population is vulnerable to infection; second, that only 7 per cent of the population has been infected so far; and third, that the virus causing Covid-19 has a mortality rate of about 1 per cent. Multiple research groups in Europe and the US have shown that around 30 per cent of the population was likely already immune to Covid-19 before the virus arrived. Sage has similarly failed to accurately revise down its estimated mortality rate for the virus. Pre-eminent scientists ... have concluded that the mortality rate is closer to 0.2 per cent. That figure means one in 500 people infected die. When applied to the total number of Covid deaths in the UK (around 45,000), this would imply that approximately 22.5million people have been infected. That is 33.5 per cent of our population – not Sage's 7 per cent calculation.
Note: The author of this article, Dr. Mike Yeadon, is a former Vice President and served as Chief Science Officer of the A&R Research Unit of Pfizer for 16 years. For more along these lines, see concise summaries of deeply revealing news articles on the coronavirus from reliable major media sources.
After the COVID-19 pandemic forced nonessential businesses to temporarily shut down across Southern California, the Los Angeles Times invited readers to send in the names of businesses in their areas that had failed as a result. [#1] The Awesome Playground was in the first wave of Los Angeles businesses to close as a result of the pandemic, shutting its doors in March. Owner Kay Osorio opened the Awesome Playground in Highland Park 10 years ago. But when the coronavirus crisis began making headlines in Southern California, Osorio knew immediately it could have a devastating effect on her business. Unlike other businesses that have been able to pivot to outdoor-only or remote offerings, "we couldn't come up with another way to deliver our service." [#2] Sasha Jones had just one day in late July to clear out Cuties Coffee before its lease was taken over. "I got an email late Thursday afternoon, like, we need to get what we can out tomorrow, Friday," the Cuties CEO said. For weeks, the threat of closure had loomed over the LGBTQ-owned and -operated coffee shop. Since the closure of the coffee shop, Cuties is continuing to operate without a physical space. [#3] When Alan Abdo negotiated with his landlord to end the lease for Olive Tree Restaurant, he remembers saying, "I can't close fast enough. I'm losing money by the minute." Olive Tree was a thriving, well-known Middle Eastern restaurant in Anaheim right up until the enforced business closures began.
Note: Small businesses have been devastated worldwide by the lockdown, yet most large corporations are thriving and the billionaires are making money hand over fist. So who is really benefitting from these lockdown measures? For more along these lines, see concise summaries of deeply revealing news articles on the coronavirus from reliable major media sources.
More and more people are going hungry, with food bank lines stretching for blocks. One solution has been popping up in cities of all sizes: community fridges. The fridges, usually colorfully painted, can be found in public spaces like sidewalks and storefronts. Volunteers and community members keep them stocked with donated food and other supplies, and people can take what they need – no questions asked. While the pandemic and subsequent economic difficulty may have accelerated their use, community fridges aren't a unique idea; Ernst Bertone Oehninger, the co-founder of Freedge, a network that provides resources and information to community fridge operators around the world, said that he believes he first started hearing about the concept in 2012. Currently, Freedge's database lists nearly 200 fridges in the United States. When it comes to starting a community fridge, organizers described the process as surprisingly easy. The most difficult part, according to Sandra Belat, 24, who is preparing to open a fridge in Denver, Colorado, is securing a location, but the community has been eager to support the initiative. Community fridge organizers are responsible for more than just putting food in fridges: They also need to keep them clean, ensure that the items inside the fridge are safe and healthy and keep the fridges stocked. In addition to food donations, many community fridges are given supplies and financial donations, so the operators can purchase items to put in the fridges.
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America's imprisonment rate has dropped to its lowest level since 1995, led by a dive in the percentage of blacks and Hispanics sent to jail during the Trump administration, according to a new Justice tally. For minorities, the focus of President Trump's First Step Act prison and criminal reform plan, the rate is the lowest in years. For blacks, the imprisonment rate in state and federal prisons is the lowest in 31 years and for Hispanics it is down 24%. "Across the decade from 2009 to 2019, the imprisonment rate fell 29% among black residents, 24% among Hispanic residents and 12% among white residents. In 2019, the imprisonment rate of black residents was the lowest it has been in 30 years, since 1989," said the report. Explaining the rate, Justice said, "At year-end 2019, there were 1,096 sentenced black prisoners per 100,000 black residents, 525 sentenced Hispanic prisoners per 100,000 Hispanic residents and 214 sentenced white prisoners per 100,000 white residents in the U.S. Among sentenced state prisoners at year-end 2018 (the most recent data available), a larger percentage of black (62%) and Hispanic (62%) prisoners than white prisoners (48%) were serving time for a violent offense." For its report, Justice counts those in prison for more than a year. The report did not cite any reasons for the drop. Trump recently led a bipartisan coalition to push through criminal reforms with the First Step Act that have helped to cut prison terms for some.
Note: See the official Bureau of Justice statistics at https://www.bjs.gov/content/pub/press/p19_pr.pdf. Explore a treasure trove of concise summaries of incredibly inspiring news articles which will inspire you to make a difference.
The development of the antibody cocktail used to treat President Donald Trump for Covid-19 – which he heralded as a cure for the disease – was funded largely by the U.S. government, yet the Trump administration has apparently failed to set any guarantees that the treatment would be affordable. The biopharmaceutical company Regeneron, led by the two highest paid executives in the industry, received hundreds of millions in public funds during the research and development of the antibody therapy, and now stands to make a killing from its potentially lifesaving treatment. In January ... Regeneron struck an agreement with a division of Department of Health and Human Services known as the Biomedical Advanced Research and Development Authority, or BARDA, to receive up to $81 million for work on antibodies that would prevent Covid-19 from infecting cells by attaching to the spikes on its surface. The two antibodies Regeneron chose were developed using cell lines that were derived from the kidney tissue of an aborted fetus. The January contract [lacks] a standard clause that ensures interventions developed with government funding are available to the public "on reasonable terms." While Trump promised that the government would provide the antibody cocktail to Americans for free, drug pricing efforts say that many people probably won't have access to the treatment at all, let alone at an affordable price. "You have massive public investment, but ... it doesn't benefit public health," [said drug pricing expert Zain Rizvi].
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Ghislaine Maxwell's answers to questions about the sex-trafficking operation she allegedly ran with the late Jeffrey Epstein were made public Thursday as a federal court released Maxwell's 2016 deposition. The transcript is finally being unsealed after a back-and-forth legal battle between Maxwell and Virginia Giuffre, who has accused Maxwell, Epstein and others of sexually abusing her when she was a minor. In it, Maxwell repeatedly denies "recruiting" girls for Epstein or taking part in orgies and other activities. Persistent allegations that Epstein sexually abused young women under the guise of receiving massages prompted an investigation by Palm Beach police in the early 2000s. Giuffre's attorney asked, "Are you aware there were underage girls, 30 of them, in this police report that were assaulted by Jeffrey Epstein in the Palm Beach house during the time you are working there?" In her reply, Maxwell said she couldn't testify about that, accusing one of Epstein's alleged victims of lying and saying that she spent only limited time at Epstein's house in 2004, the year in question. For years, accusations against Maxwell and Epstein were obscured by legal maneuvers – most famously, a controversial nonprosecution agreement Epstein reached in 2007 with federal prosecutors in Florida. That plea deal with then-U.S. Attorney Alex Acosta led to state charges against Epstein, but it also prevented him and any co-conspirators – including, allegedly, Maxwell – from being prosecuted in federal sex crimes in southern Florida.
Note: For more along these lines, see concise summaries of deeply revealing news articles on Jeffrey Epstein's sex trafficking ring from reliable major media sources.
Cats are unable to distinguish between street clothes and prison uniforms – and that's exactly what makes the relationship between the men at Pendleton Correctional Facility, a maximum-security prison outside of Indianapolis, and the cats that live there, so special. For six hours a day, seven days a week, a handful of men receive unqualified love from the more than 20 cats that live in the prison as part of the FORWARD program, or Felines and Offenders Rehabilitation with Affection, Reformation and Dedication. In exchange for care and a place to stay before being adopted, the cats at Pendleton offer inmates untampered, non-judgemental affection. Through the 5-year-old program, a select few incarcerated men are paid 20 cents an hour to spend their days caring for abandoned and abused cats, preparing them for adoption. Or, as some inmates will say, for a reason to get up in the morning. In partnership with the Animal Protection League of Indiana, the program removes cats from a traditional shelter and places them in the prison's "cat sanctuary," a wide-open room with scratching posts, climbing structures and nooks to hide in. The program houses them with incarcerated caregivers, who, incidentally, gain skills such as empathy, responsibility and self-esteem. The caregivers spend their days cleaning the cat sanctuary, changing litter boxes, and feeding and giving water to the cats. Everything but medical care is under the inmates' purview. The work, albeit behind prison walls, is a full-time job.
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Previous vaccines have taken a decade or more to develop, and more than half of the past 20 years have failed in clinical trials. However, four [COVID-19] vaccine candidates have entered the final phase of clinical trials prior to approval by the Food and Drug Administration. Operation Warp Speed ... organized government agencies and private companies with the goal of developing, manufacturing and distributing hundreds of millions of vaccine doses, with starting doses to be available by early 2021. At the head of the operation is Moncef Slaoui, a Moroccan-born Belgian-American scientist. Operation Warp Speed … has invested in six vaccine candidates (Moderna, Pfizer / BioNTech, Johnson & Johnson, AstraZeneca, Novavax, and Sanofi / GSK) with the hope that at least one ... will prove safe and effective in clinical trials. Four of the six vaccine candidates have already been shown to be safe and effective in the first two test phases, which test whether the vaccinations produce so-called neutralizing antibodies. Serious health problems regularly arise during vaccination attempts. "We know how to distribute vaccines to any location in the US," says Slaoui. "It happens every year for flu and shingles." Tracking systems need to be "incredibly precise" to ensure that patients are each given two doses of the same vaccine and to monitor them for adverse health effects. Operation Warp Speed … has selected medical distributor McKesson and cloud operators Google and Oracle to collect and track vaccine data.
Note: The above article is also available here. Don't miss this excellent article which raises many important questions about this operation. For more along these lines, see concise summaries of deeply revealing news articles on the coronavirus and vaccines from reliable major media sources.
Voter suppression has taken centre stage in the race to elect potentially the 46th president of the United States. But we've heard little about the 5.2 million Native Americans whose ancestors have called this land home before there was a US president. The rights of indigenous communities – including the right to vote – have been systematically violated for generations with devastating consequences. Voter turnout for Native Americans and Alaskan Natives is the lowest in the country, and about one in three eligible voters (1.2 million people) are not registered to vote. In a new book, Voting in Indian County: The View from the Trenches, Jean Reith Schroedel ... at Claremont Graduate University weaves together historical and contemporary voting rights conflicts. American Indians and Native Alaskans were the last group in the United States to get citizenship and to get the vote. Some laws used to disenfranchise them were still in place in 1975. Voting by mail is very challenging for Native Americans for multiple reasons. First and foremost, most reservations do not have home mail delivery. Instead, people need to travel to post offices or postal provide sites – little places that offer minimal mail services and are located in places like gas stations and mini-marts. Take the Navajo Nation that encompasses 27,425 square miles – it's larger than West Virginia, yet there are only 40 places where people can send and receive mail. In West Virginia, there are 725. Not a single PO box on the Navajo Nation has 24-hour access.
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Evidence of what appears to be aggressive animal abuse, practices leading to heightened disease risk and cows being passed off as organic at a Texan auctioneers has been presented to the US Department of Agriculture (USDA) by undercover welfare investigators. The ... investigation centres on Texan auctioneers, Erath County Dairy Sales (ECDS). Undercover video footage filmed at ECDS between January and March 2020 ... was delivered to the USDA by the US-Brazil based NGO, Strategies for Ethical and Environmental Development (Seed). In one video, the undercover investigator, hired as an animal handler, is told that removing a cowâ₏™s ear tags, and replacing them with new â₏Œback tagsâ₏ť that indicate a cow is organic, can triple or quadruple their meat sale value. The investigator said he witnessed the tag switching process. First, a bladed tool was used to remove the ear tags, which are part of the USDAâ₏™s animal disease traceability framework. These tags were not replaced. Instead, another tag, known as a back tag or sticker, was glued to the cowâ₏™s back. The stickers indicate the cow is organic and from Texas. A lawyer for California-based NGO, Animal Legal Defense Fund, said she was â₏Œnot too surprisedâ₏ť by the tag switching accusations. â₏ŒWe have seen this type of thing before,â₏ť said Kelsey Eberly. She fears the practice is â₏Œmore commonâ₏ť than people would expect, mainly â₏Œbecause the price premium is so much higherâ₏ť for organic and better welfare meat and dairy.
Note: For more along these lines, see concise summaries of deeply revealing news articles on food system corruption from reliable major media sources.
The New York Times Guild, the union of employees of the paper of record, tweeted a condemnation on Sunday of one of their own colleagues, op-ed columnist Bret Stephens. What angered the union today was an op-ed by Stephens on Friday which voiced numerous criticisms of the Pulitzer Prize-winning “1619 Project,” published last year by the New York Times Magazine. One of the Project’s principal arguments was expressed by a now-silently-deleted sentence that introduced it: “that the country’s true birth date” is not 1776, as has long been widely believed, but rather late 1619, when, the article claims, the first African slaves arrived on U.S. soil.” The 1619 Project has become a major controversy. In his Friday column, Stephens addressed the controversy by first noting the Project’s positive contributions and accomplishments, then reviewed in detail the critiques of historians and other scholars of its central claims, and then sided with its critics by arguing that “for all of its virtues, ... the 1619 Project has failed.” But his colleagues in the New York Times Guild evidently do not believe that he had any right to express his views on these debates. In a barely-literate tweet that not once but twice misspelled the word “its” as “it’s” — not a trivial level of ignorance for writers with the world’s most influential newspaper — the union denounced Stephens and the paper itself on these grounds: "It says a lot about an organization when it breaks it's own rules and goes after one of it's own. The act, like the article, reeks."
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The New Leaf project is a joint study started in 2018 by Foundations for Social Change, a Vancouver-based charitable organization, and the University of British Columbia. After giving homeless Lower Mainland residents cash payments of $7,500, researchers checked on them over a year to see how they were faring. All 115 participants, ranging in age between 19 and 64, had been homeless for at least six months. Of those, 50 people were chosen at random to be given the cash, while the others formed a control group that did not receive any money. "I had no expectations and really high hopes," said Claire Williams, CEO of Foundations for Social Change. What researchers found after 12 months, she said, was "beautifully surprising." Not only did those who received the money spend fewer days homeless than those in the control group, they had also moved into stable housing after an average of three months. On average, cash recipients spent 52 per cent of their money on food and rent, 15 per cent on other items such as medications and bills, and 16 per cent on clothes and transportation. In comparison, spending on alcohol, cigarettes and drugs went down, on average, by 39 per cent. [Williams] said it costs, on average, $55,000 annually for social and health services for one homeless individual. According to study data, the project saved the shelter system approximately $8,100 per person for a total of roughly $405,000 over one year for all 50.
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Something as simple as saying hello to a stranger can enhance your happiness and feelings of well-being in these troubled times, two new studies show. In one survey, a sampling of 856 commuters who initiated "positive social interactions" with their bus or shuttle drivers had greater levels of being satisfied with themselves and their lives. In the other, a group of 265 travelers were split into two groups. Half were told to strike up a positive interaction with their driver by saying "have a nice day" or "thank you" upon leaving the bus, in a warm and sincere way. They were also told to make eye contact. The other half of participants was told not to speak to their driver. The commuters were surveyed after they got off their buses. The first group reported more positive feelings and well-being than the travelers who didn't talk to their drivers. Both studies were recently published as a paper titled "Minimal Social Interactions with Strangers Predict Greater Subjective Well-Being," in the Journal of Happiness Studies. "Simply taking a moment to greet, express good wishes, or say thank you to strangers is linked with greater happiness in everyday life," the authors wrote. So if the coronavirus pandemic is on your last nerve, try a simple hello to the person behind the wheel on your next bus ride.
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Rep. Katie Porter (D-Calif.) got out her marker and scrawled a figure on the whiteboard beside her: $13 million. “Do you know what this number is?” she asked Mark Alles, the former CEO of the pharmaceutical company Celgene, as he testified remotely before the House Oversight Committee on Wednesday. “Does it ring any bells?” Alles could hardly get his answer out before Porter scribbled more math on the board. That multimillion figure — his total compensation in 2017 — was already 200 times the average income in the United States, the congresswoman pointed out. It got even larger, she said, after Celgene needlessly tripled the cost of a cancer medication, thus securing himself hefty bonuses in return. As of early Thursday, the rapid-fire interrogation had been viewed more than 15 million times on Twitter — the latest in a long list of her viral cross-examinations. These stunning exchanges at congressional hearings have themselves gained plenty of attention beyond Capitol Hill — especially when Porter pulls out what one person on Twitter dubbed “her mighty whiteboard of truth.” It is this kind of clear, insistent inquiry that has made Porter — a consumer protection lawyer ... who studied bankruptcy law under Sen. Elizabeth Warren (D-Mass.) — so effective at grilling everyone from Mark Zuckerberg to little-known Trump appointees, all with a dry-erase marker and some simple math. “No one has ever wielded a weapon as terrifying as Katie Porter’s whiteboard,” wrote Molly Wood, a public radio journalist.
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Prescription drug prices in the U.S. are expensive. One vial of insulin can cost as much as $450, while the same amount goes for about $30 in Canada. Now, California could make its own generic insulin - and other prescription drugs - through a new law passed this week that aims to increase access to affordable medications. California governor Gavin Newsom signed legislation this week that allows the California Health and Human Services Agency to partner with drug manufacturers in order to make or distribute generic prescription drugs. The bill builds on a plan Newsom first announced in January to increase generic drug manufacturing, which would lower prescription drug costs through a state-sponsored prescription drug label called Cal Rx. Cal Rx wouldn’t be developing new drugs ... just attempting to make cheaper versions of generic drugs, or drugs that aren’t currently covered by a patent. The bill does not specify what prescription drugs the state’s health agency would create or distribute through such partnerships - officials are in the process of identifying potential medications - but it does require a partnership for “at least one form of insulin, provided that a viable pathway for manufacturing a more affordable form of insulin exists at a price that results in savings.” Current U.S. laws allow pharmaceutical manufacturers to set their own prices, which isn’t common practice in other countries. In England ... a government agency negotiates directly with pharmaceutical companies.
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