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Note: Explore our full index to key excerpts of revealing major media news articles on several dozen engaging topics. And don't miss amazing excerpts from 20 of the most revealing news articles ever published.
Japanese health authorities are investigating a flu medicine that is also available in Australia after a teenager jumped 11 storeys to his death after taking the drug. It was the 18th juvenile fatality linked to Tamiflu in 17 months. The Ministry of Health, Labour and Welfare has asked the Japanese importer of Tamiflu, an anti-viral drug regarded as the most important shield against bird flu in humans, to collect information about the conditions of patients who take the drug. The 14-year-old boy's death follows a similar case two weeks ago, when a girl also 14, died after jumping from an apartment building at Gamagori, in central Japan. It also comes after a warning by the US Food and Drug Administration late last year about the dangers of giving children Tamiflu. The drug is being stockpiled in Australia as the first line of defence against bird flu. In Australia, as in Japan, it is only available by prescription. Drug companies reported that 54 people using Tamiflu died in Japan before November, the ministry said.
Note: Tamiflu is the vaccine on which Donald Rumsfeld profited $5 million and on which the U.S. government has spent hundreds of millions of dollars stockpiling, even though it might not work. For more, click here.
A Florida man with no medical training has invented a machine that he believes may lead to a cure for cancer. John Kanzius ... wondered if his background in physics and radio could come in handy in treating the disease from which he suffers himself. After 24 rounds of chemotherapy, the former broadcaster decided that he did not want to see others suffer trying to cure the disease. Kanzius said it was watching kids being treated that affected him the most. "Particularly, young children walk in with smiles, and then you'd see them three weeks later and their smiles had disappeared. I said to myself, 'We're in a barbaric type of medicine." Kanzius said his machine basically makes cells act like antennae to pick up a signal and self-destruct. Unlike current cancer treatment, Kanzius' machine does not use radiation, and unlike today's radio-frequency treatments, it's noninvasive. Now, some of the nation's most prominent doctors and scientists are using Kanzius' machines in their research. In January, researchers said they performed a breakthrough at the M. D. Anderson Cancer Center in Houston. "The complete killing of pancreatic cells in laboratory conditions is encouraging," Dr. Steve Curley said. Kanzius explained that his machine uses a solution filled with nanoparticles, which measure no more than one-billionth of a meter. A test subject would be injected with either gold or carbon nanoparticles, which would make their way through the body and attach to the cancerous cells. The test subject would then enter the machine and receive a dose of radio frequency waves, theoretically heating and killing the cancerous cells in moments and leaving nearby cells untouched.
Note: For more on this exciting machine and the man behind it, click here. For other major media articles relating potential cancer cures, click here.
Gov. Rick Perry on Thursday angrily defended his relationship with Merck & Co. and his executive order requiring that schoolgirls receive the drugmaker's vaccine against the sexually transmitted cervical-cancer virus. The Associated Press reported Wednesday that Perry's chief of staff had met with key aides about the vaccine on Oct. 16, the same day Merck's political action committee donated $5,000 to the governor's campaign. In issuing the order, the governor made Texas the first state to require the vaccine Gardasil for all schoolgirls. But many lawmakers have complained about his bypassing the Legislature altogether. The executive order has inflamed conservatives, who said it contradicts Texas' abstinence-only sexual education policies and intrudes into families' lives. Critics have previously questioned Perry's ties to Merck. Mike Toomey, Perry's former chief of staff, now lobbies for the drug company. And the governor accepted a total of $6,000 from Merck during his re-election campaign. Merck has waged a behind-the-scenes lobbying campaign to get state legislatures to require girls to get the three-dose vaccine to enroll in school. But on Tuesday the pharmaceutical company announced it was suspending the effort because of pressure from parents and medical groups. The Kentucky House on Thurday passed a bill that would require the vaccination for middle school girls unless their parents sign a form opposing it. Virginia lawmakers have also passed legislation requiring the vaccine, but the governor has not decided if he will sign it.
Note: The drug company lobby is the most powerful in the U.S., as reported by the former editor-in-chief of one of the most respected medical journals in the U.S. Click here for more.
Pediatricians, gynecologists and even health insurers all call Gardasil, the first vaccine to prevent cervical cancer, a big medical advance. But medical groups, politicians and parents began rebelling after disclosure of a behind-the-scenes lobbying campaign by Gardasil's maker, Merck & Co., to get state legislatures to require 11- and 12-year-old girls to get the three-dose vaccine as a requirement for school attendance. Some parents' groups and doctors particularly objected because the vaccine protects against a sexually transmitted disease. Vaccines mandated for school attendance usually are for diseases easily spread through casual contact, such as measles and mumps. Bowing to pressure, Merck said Tuesday that it is immediately suspending its controversial campaign, which it had funded through a third party. Legislatures in roughly 20 states have introduced measures that would mandate girls have the vaccine to attend school. Texas Gov. Rick Perry on Feb. 2 issued an executive order requiring Texas girls entering the sixth grade as of 2008 get the vaccinations. Dr. Anne Francis, who chairs an American Academy of Pediatrics committee [stated] "I believe that their timing was a little bit premature," she said, "so soon after (Gardasil's) release, before we have a picture of whether there are going to be any untoward side effects." The country has been "burned" by some drugs whose serious side effects emerged only after they were in wide use, including Merck's withdrawn painkiller Vioxx. The vaccine also is controversial because of its price - $360 for the three doses required.
Note: $360 for every girl in school would amount to quite a hefty transfer of funds from taxpayers into the pockets of Merck. Could profit and campaign contributions be behind the move to make this mandatory?
Cities should close schools for up to three months in the event of a severe flu outbreak, ball games and movies should be canceled ... the federal government advised today in issuing new pandemic flu guidelines to states and cities. Health officials acknowledged that such measures would hugely disrupt public life, but they argued that these measure would buy the time needed to produce vaccines and would save lives. “We have to be prepared for a Category 5 pandemic,” said Dr. Martin Cetron, director of global migration and quarantine for the Centers for Disease Control and Prevention. “It’s not easy. The only thing that’s harder is facing the consequences.” The new guidelines also advocate having sick people and all their families' even apparently healthy members stay home for 7 to 10 days. Any pandemic is expected to move faster than a new vaccine can be produced. Current experimental vaccines against H5N1 avian flu are in short supply and based on strains isolated in 2004 or 2005. Although the government is creating a $4 billion stockpile of the antiviral drug Tamiflu, it is only useful when taken within the first 48 hours, and Tamiflu-resistant flu strains have already been found. The historian John Barry, author of “The Great Influenza,” a history of the 1918 flu, questioned an idea underpinning the study’s conclusions. There is evidence, he said, that some cities with low sickness and death rates in 1918 ... were hit by a milder spring wave of the virus. That would have, in effect, inoculated their citizens against the more severe fall wave and might have been more important than their public health measures.
Note: Why is it that government officials seem to want us to be afraid? Could it be that when we live in fear, we are more willing to give up our freedoms and money and allow them to be in control? For more, click here. And why would the government spend billions on stockpiling drugs of questionable use? For an answer, click here.
The U.S. Food and Drug Administration said on Tuesday it would make organizational changes to improve internal communication about potential risks that emerge after a new drug reaches the market. The move is part of the agency's response to an Institute of Medicine (IOM) report that sharply criticized the FDA's drug safety oversight and called for more staffing, funding and power to police the drug industry. The September 2006 report also found a "dysfunctional" FDA structure that hindered the agency's ability to protect public health. The IOM experts said they found FDA officials had trouble managing scientific disagreements among staff and downplayed some concerns by safety reviewers who monitor drugs after they win approval. On Tuesday, the agency said it was "making specific organizational and management changes to increase communications among FDA review staff and safety staff." The announcement came as lawmakers prepare to debate critical funding legislation for the agency that could become a vehicle for drug safety reforms. The FDA had requested the IOM report after it came under harsh criticism for its handling of Merck & Co. Inc.'s withdrawn arthritis drug Vioxx and other medicines. Merck pulled Vioxx from the market in 2004, five years after its approval, because of a link to heart attacks and strokes.
Secret emails reveal that the UK's biggest drug company distorted trial results of an anti-depressant, covering up a link with suicide in teenagers. GlaxoSmithKline (GSK) attempted to show that Seroxat worked for depressed children despite failed clinical trials. And that GSK-employed ghostwriters influenced 'independent' academics. GSK faces action in the US where bereaved families have joined together to sue the company. As a result, GSK has been forced to open its confidential internal archive. Karen Barth Menzies is a partner in one of the firms representing many of the families. She has examined thousands of the documents which are stored, box upon box, in an apartment in Malibu, California. She said: "Even when they have negative studies that show that this drug Seroxat is going to harm some kids they still spin that study as remarkably effective and safe for children." An email from a public relations executive working for GSK ... said: "Originally we had planned to do extensive media relations surrounding this study until we actually viewed the results. Essentially the study did not really show it was effective in treating adolescent depression, which is not something we want to publicise." Seroxat was banned for under 18s in 2003 after the MHRA revealed that GSK's own studies showed the drug actually trebles the risk of suicidal thoughts and behaviour in depressed children.
Note: For more reliable information on how the drug companies put profits ahead of your health, click here.
Fluoride has become a controversial additive to our drinking water. While no one denies it can prevent cavities with topical application, a growing number of people, cities and countries have decided that ingesting unknown quantities of fluoride is a bad idea. One of Tennessee's own top health risk scientists is asking Gov. Phil Bredesen to stop adding fluoride to the water. Dr. Kathy Thiessen makes a living assessing health risks and has worked for the Center for Disease Control and Prevention and the Environmental Protection Agency. “The deliberate exposure to uncontrolled and unmonitored intake of fluoride is unwise at best and probably harmful to a substantial number of people,” Thiessen said. Thiessen joins Tennessee lawmaker and medical doctor Joey Hensley as the most prominent Tennessee voices against fluoride. Chris White is a musician with the band Loft, but his other passion is removing fluoride from Gallatin's water supply. “All parties point to the American Dental Association recommending that mothers stop using fluoridated water for baby formula as an obvious sign that fluoride is obviously not for everyone,” he said.
Note: This article fails to mention a key recent study showing "about 28 percent of the children in the low-fluoride area scored as bright, normal or higher intelligence compared to only 8 percent in the 'high' fluoride area. In the high-fluoride city, 15 percent had scores indicating mental retardation and only 6 percent in the low-fluoride city." For a truly awesome, revealing interview with a BBC producer on the major deceptions around and dangers of fluoride in water, click here. For more on this key topic from Dr. Mercola, click here. And for the top website on the risks and dangers of flouride in water, click here.
A new breed of lifestyle drugs could allow us to choose how much we sleep, boost our memories and even allow us to enjoy ourselves more, without any side effects. Will they unleash human capabilities never seen before or create a dystopian 24-hour society where we are dependent on drugs to regulate our lifestyle and behavior? One drug already available is modafinil, marketed as the vaguely Orwellian-sounding Provigil. It enables those who take it to stay awake and alert for 48 hours. It is a eugeroic that delivers a feeling of wakefulness without the physical or mental jitter. There is already a market for it for those without any medical need - it is developing a cult following among workaholics and students studying for exams. The military is also very interested in eugeroic. Their reliance on amphetamines for lengthy operations have had catastrophic consequences in the past. The "friendly-fire" incidents in Afghanistan in 2002 when U.S. pilots killed Canadian troops was blamed on the "go pills" they had taken. The U.S. Defense Advanced Research Projects Agency (DARPA) tested a compound called CX717 in its quest to find a drug that can create a "metabolically dominant war-fighter of the future" able to function for seven days without sleep. CX717 is an ampakine, a compound that increases the brains computing powers. It re-writes the rules of what it takes to create a memory and just how strong those memories can be. Will cans of soda containing eugeroics or ampakines be as common as caffeine drinks on the shelves of 24-hour stores? The potential is certainly there for a brave new world of personality medication.
There are no magic bullets in the fight against cancer: that's the first thing every responsible scientist mentions when discussing a possible new treatment, no matter how promising. If there were a magic bullet, though, it might be something like dichloroacetate, or DCA, a drug that kills cancer cells by exploiting a fundamental weakness found in a wide range of solid tumors. So far, though, it kills them just in test tubes and in rats infected with human cancer cells; it has never been tested against cancer in living human beings. DCA ... is an existing drug whose side effects are well-studied and relatively tolerable. Also, it's a small molecule that might be able to cross the blood-brain barrier to reach otherwise intractable brain tumors. Within days after a technical paper on DCA appeared in the journal Cancer Cell last week, the lead author, Dr. Evangelos Michelakis of the University of Alberta, was deluged with calls and e-mails from prospective patients—to whom he can say only, “Hang in there.” DCA is a remarkably simple molecule. It acts in the body to promote the activity of the mitochondria. Researchers have assumed that the mitochondria in cancer cells were irreparably damaged. But Michelakis wondered if that was really true. With his colleagues he used DCA to turn back on the mitochondria in cancer cells—which promptly died. One of the great things about DCA is that it's a simple compound, in the public domain, and could be produced for pennies a dose. But that's also a problem, because big drug companies are unlikely to spend a billion dollars or so on large-scale clinical trials for a compound they can't patent.
Note: Read a 2010 follow-up by Dr. Michelakis with promising results and watch a 10-minute video. Explore the DCA website. Why didn't other mass media report this major story? Why aren't many millions of dollars being poured into research? Notice even Newsweek acknowledges the drug companies are not interested in finding a cure for cancer if they can't make a profit from it. Some suspect the drug companies have even suppressed cancer cures found in the past. See one amazing example of this. For more, see these major media articles on potential cancer cures.
Dr. Brooke Herndon, an internist at Dartmouth-Hitchcock Medical Center, could not stop coughing. Dr. Kathryn Kirkland, an infectious disease specialist at Dartmouth, had a chilling thought: Could she be seeing the start of a whooping cough epidemic? By late April, other health care workers at the hospital were coughing. It was the start of a bizarre episode at the medical center: the story of the epidemic that wasn’t. For months, nearly everyone involved thought the medical center had had a huge whooping cough outbreak, with extensive ramifications. Nearly 1,000 health care workers ... were given a preliminary test and furloughed from work until their results were in; 142 people, including Dr. Herndon, were told they appeared to have the disease; and thousands were given antibiotics and a vaccine for protection. The whole thing was a false alarm. Now, as they look back on the episode, epidemiologists and infectious disease specialists say the problem was that they placed too much faith in a quick and highly sensitive molecular test that led them astray. Such tests are coming into increasing use and may be the only way to get a quick answer in diagnosing diseases like whooping cough, Legionnaire’s, bird flu, tuberculosis and SARS. There are no good estimates of their error rates. But their very sensitivity makes false positives likely, and when hundreds or thousands of people are tested, as occurred at Dartmouth, false positives can make it seem like there is an epidemic.
Note: For more along these lines, see concise summaries of deeply revealing news articles on health from reliable major media sources.
The two sides in the debate over genetically modified crops issued warring reports assessing the first decade of the technology this week, as the industry's sunny view clashed with the darker vision of critics. The world's farmland planted with biotechnology crops reached 252 million acres in 2006, the industry-backed International Service for the Acquisition of Agri-Biotech Applications calculated in a report ... that promotes the products as solutions for hunger and future fuel demand. The report concluded that biotechnology boosts crop yields and benefits the environment. That view was challenged by Friends of the Earth International and the Center for Food Safety in a report released Wednesday. The two groups argued that engineered plants don't produce larger harvests than conventional varieties, are often more vulnerable to drought and have increased the use of pesticides. The United States and Argentina host about 70 percent of the world's biotech crop acreage, both sides said. But adoption of the technology is growing at a faster rate in developing countries than in industrialized nations, according to the International Service. About 10 million farmers in 22 countries sow genetically modified crops, it said. The dominant biotech crop is soybeans, with 57 percent of world acreage, followed by maize, cotton and canola. Opponents said the crops are mainly a boon to agribusiness and big agricultural chemical companies trying to increase sales of seeds, weed-killers and bug sprays. Biotech crop seeds are often engineered to be resistant to the herbicides or pesticides sold by the same company.
Note: For reliable information showing that you may be eating genetically modified food every day which scientific experiments have repeatedly demonstrated can cause sickness and even death, click here.
Data supplied by tobacco companies strongly suggest that in recent years manufacturers deliberately boosted nicotine levels in cigarettes to more effectively hook smokers, Harvard researchers conclude in a study being released today. The companies increasingly used tobacco richer in nicotine and made design changes to give smokers more puffs per cigarette, according to the analysis from the Harvard School of Public Health. The report expands on a landmark Massachusetts Department of Public Health study issued last August showing that the amount of nicotine that could be inhaled from cigarettes increased an average of 10 percent from 1998 through 2004. A 1996 state law required cigarette makers to test the nicotine that could be inhaled from their products, and the state ordered the use of machines that simulate a typical smoker's puffing. The Harvard researchers, who corroborated the basic findings of the state study, wanted to determine why cigarettes were delivering more nicotine. "Industry says it's changed," said Greg Connolly, an author of the Harvard study. "They've changed -- maybe for the worse." The Harvard study relies on information supplied by the industry. "It was systematic, it was pervasive, it involved all the manufacturers, and it was by design," said Dr. Howard Koh, an associate dean at the Harvard School of Public Health and an author of the study. Another author said that the likelihood that the nicotine increase happened by chance was less than 1 in 1,000.
In results that "astounded" scientists, an inexpensive molecule known as DCA was shown to shrink lung, breast and brain tumours in both animal and human tissue experiments. The study was published yesterday in the journal Cancer Cell. "I think DCA can be selective for cancer because it attacks a fundamental process of cancer that is unique to cancer cells," said Dr. Evangelos Michelakis, a professor at the Edmonton university's medical school and one of the study's key authors. The molecule appears to repair damaged mitochondria in cancer cells. "When a cell is getting too old or doesn't function properly, the mitochondria are going to induce the cell death," lead study author Sebastien Bonnet said yesterday. Bonnet says DCA – or dichloroacetate – appears to reverse the mitochondrial changes in a wide range of cancers. "One of the really exciting things about this compound is that it might be able to treat many different forms of cancer because all forms of cancer suppress mitochondrial function," Michelakis said. Bonnet says DCA may also provide an effective cancer treatment because its small size allows easy absorption into the body, ensuring it can reach areas that other drugs cannot, such as brain tumours. Because it's been used to combat other ailments ... DCA has been shown to have few toxic effects on the body. Its previous use means it can be immediately tested on humans. Unlike other cancer drugs, DCA did not appear to have any negative effect on normal cells. It could provide an extremely inexpensive cancer therapy because it's not patented. But ... the lack of a patent could lead to an unwillingness on the part of pharmaceutical companies to fund expensive clinical trials.
Note: Even these scientists realize that though this discovery could be a huge benefit to mankind, because the drug companies will lose profits, they almost certainly will not fund studies. Expensive AIDS drugs with promising results, on the other hand, are rushed through the studies to market. For more reliable, verifiable information on how hugely beneficial health advances are shut down to keep profits high, click here and here.
A team at the institute that cloned Dolly the sheep have made a genetically engineered chicken that produces cancer drugs in its eggs. The chickens produce the cancer drugs in their egg whites, the team at the Roslin Biocentre in Edinburgh reported. The drugs include a monoclonal antibody — themselves lab-engineered immune system proteins — and a human immune system protein used to treat cancer and other conditions. Scientists have been trying to find good ways to turn animals into factories. Cattle, sheep and goats all have been genetically engineered to produce human proteins in their milk, including insulin and drugs to treat cystic fibrosis, but the Roslin team thought chickens, with their shorter life cycles and egg-laying prowess, also might be useful. They used a virus to infect very early chicken embryos. The virus inserted the genetic material into the DNA of chick embryos in newly laid eggs. The researchers hatched these chicks and found the male chicks who had indeed incorporated the new DNA in their semen. These cockerels were then bred with normal hens and they screened the resulting chicks to see which ones still carried the two new genes. The researchers have now bred several hundred chickens that can produce the desired proteins. Other companies have created animals and plants that produce human and animal proteins, as well as vaccines.
Note: It's a brave new world. For more on genetically modified organisms, click here.
Two UK-based academics have devised a way to invent new medicines and get them to market at a fraction of the cost charged by big drug companies. Sunil Shaunak, professor of infectious diseases at Imperial College ... calls their revolutionary new model "ethical pharmaceuticals". Improvements they devise to the molecular structure of an existing, expensive drug turn it technically into a new medicine which is no longer under a 20-year patent to a multinational drug company and can be made and sold cheaply. The process has the potential to undermine the monopoly of the big drug companies and bring cheaper drugs not only to poor countries but back to the UK. Professor Shaunak and his colleague from the London School of Pharmacy, Steve Brocchini, have linked up with an Indian biotech company which will manufacture the first drug - for hepatitis C. Hepatitis C affects 170 million people worldwide and at least 200,000 in the UK. Multinational drug companies put the cost of the research and development of a new drug at $800m (Ł408m). Professors Shaunak and Brocchini say the cost of theirs will be only a few million pounds. Professor Shaunak says it is time that the monopoly on drug invention and production by multinational corporations - which charge high prices because they need to make big profits for their shareholders - was broken. The team's work on the hepatitis C drug has impeccable establishment credentials. But the professors' ethical pharmaceutical model is unlikely to find much favour with the multinational pharmaceutical companies, which already employ large teams of lawyers to defend the patents which they describe as the lifeblood of the industry.
Note: This is very exciting news, but we'll see what happens when the hugely profitable pharmaceutical industry presses its might against this effort. For more, click here.
[Book Review of] Medical Apartheid: The Dark History of Medical Experimentation on Black Americans From Colonial Times to the Present. Harriet Washington opens the door on the torture room in "Medical Apartheid". Experimental operations on the skulls of slave children, Washington writes, were a favorite pursuit of a particularly sadistic South Carolinian doctor named J. Marion Sims, widely revered today as the "father of gynecology." For years, Sims experimented on a group of slave women, to whom he refused anesthesia. The most notorious post-slavery racial crime of American medicine [was] the Tuskegee Syphilis Study, conducted by the U.S. Public Health Service between 1932 and 1972. More than 100 black subjects ... were denied treatment, even and especially after the discovery of penicillin in 1943. The research required that they suffer and die, the more slowly the better. Tuskegee was hardly unique. The Rockefeller Institute ... conducted a study in 1910 that saw 470 black syphilitics injected with a deadly strain of malaria. Black Americans were also disproportionately used ... as subjects in government inquiries into the effects of radiation. Washington's chilling history ends with contemporary case studies. At the Incarnation Children's Center in New York, Columbia University doctors continue to administer experimental AIDS drugs to minority orphans, even after many develop painful and debilitating reactions. As for current clinical trials in Africa, Washington describes the continent as the new "laboratory for the West," where unsuspecting patients regularly receive experimental therapies that might never receive state sanction in the United States or Europe.
Note: For more reliable, verifiable information on major corruption in the health industry, click here. It's also interesting to not that no other major media chose to review this important book.
Consumer advocates and others have complained bitterly in recent years that the Food and Drug Administration has veered from its scientific roots. Later this week, the agency is expected to release a formal recommendation that milk and meat from cloned animals should be allowed on grocery store shelves. The long-awaited decision comes as polling data to be released this week show that the public continues to have little appetite for such food, with many people saying the FDA should keep it off the market. That raises the issue: Should decisions such as this one be based solely on science, or should officials take into account public sensitivities, which may be unscientific but are undeniably real? "There is more to this issue than just food safety," said Susan Ruland of the International Dairy Foods Association, which represents such major companies as Kraft Foods and Dannon. The organization's member companies are concerned that sales of U.S. dairy products could drop by 15 percent or more if the FDA allows the sale of meat and milk from clones. Relatively few cloned farm animals exist; there are an estimated 150 clones out of the nation's 9 million dairy cows. But biotechnology companies are gearing up to clone farmers' tastiest cattle and pigs and most productive dairy cows. In the University of Maryland survey, nearly half of those polled asserted that it was not yet possible to clone farm animals for food. For the most part, people don't know this is a reality yet.
The drug maker Eli Lilly has engaged in a decade-long effort to play down the health risks of Zyprexa, its best-selling medication for schizophrenia, according to hundreds of internal Lilly documents and e-mail messages among top company managers. The documents ... show that Lilly executives kept important information from doctors about Zyprexa’s links to obesity and its tendency to raise blood sugar — both known risk factors for diabetes. Lilly’s own published data, which it told its sales representatives to play down in conversations with doctors, has shown that 30 percent of patients taking Zyprexa gain 22 pounds or more after a year on the drug, and some patients have reported gaining 100 pounds or more. But Lilly was concerned that Zyprexa’s sales would be hurt if the company was more forthright about the fact that the drug might cause unmanageable weight gain or diabetes, according to the documents, which cover the period 1995 to 2004. Zyprexa has become by far Lilly’s best-selling product, with sales of $4.2 billion last year, when about two million people worldwide took the drug. Critics, including the American Diabetes Association, have argued that Zyprexa, introduced in 1996, is more likely to cause diabetes than other widely used schizophrenia drugs. As early as 1999, the documents show that Lilly worried that side effects from Zyprexa, whose chemical name is olanzapine, would hurt sales. “Olanzapine-associated weight gain and possible hyperglycemia is a major threat to the long-term success of this critically important molecule,” Dr. Alan Breier wrote in a November 1999 e-mail message to two-dozen Lilly employees.
Note: For lots more on corporate corruption from reliable sources, click here.
A Toronto-led team of researchers has discovered a trigger for Type 1 diabetes, a breakthrough that has long evaded scientists and could lead the way to preventing the disease. The team found that abnormal nerve endings in the insulin-producing cells of the pancreas initiated a chain of events that caused Type 1 diabetes in mice. When they removed the nerve cells, the mice did not develop the disorder. That means diabetes may be a disease of the nervous system, not just an autoimmune disease, said Dr. Hans Michael Dosch, a senior scientist at the Hospital for Sick Children and the study's main investigator. In a reversal of what they expected, the researchers also found injecting substance P — a chemical secreted by nerve cells — into mice whose islet cells were inflamed and on the way to being destroyed not only eliminated the inflammation but reversed it. "The blood glucose normalizes overnight and it stays low for weeks to months — this is with a single shot," Dosch said. "We now have 4-month-old mice that are non-diabetic that used to be diabetic" — a period equivalent to six to eight years in humans. Experts say the findings, reported yesterday in the journal Cell, will change the way scientists think about diabetes. "It really is a breakthrough for the diabetes community," said Pam Ohashi, a professor of immunology at the University of Toronto. Dosch has immediate plans to move his research from mice to humans. He is launching a clinical trial in January to figure out if patients who have a high risk of Type 1 diabetes have the same sensory nerve abnormalities. "If they do, then we have fantastic new therapeutic strategies," said Dosch, who is also a professor of pediatrics and immunology at U of T.
Note: The pharmaceutical industry makes huge profits from diabetics. Big profits have been known to prevent cures from making it to market. Click here for more. Let's hope this important research moves forward.
Important Note: Explore our full index to key excerpts of revealing major media news articles on several dozen engaging topics. And don't miss amazing excerpts from 20 of the most revealing news articles ever published.