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High doses of vitamin C injected into the blood stream could prove effective in treating cancer, according to new research. Scientists said vitamin C infusions, which were up to 1,000 times higher than recommended intake levels, selectively targeted tumour cells in cancer patients. This increased the rates of cell deaths and sensitised them to radiation and chemotherapy. The treatment also appeared to be safe, producing mild side effects such as frequent bathroom trips and a dry mouth. Eleven brain cancer patients were given three infusions of vitamin C a week for two months followed by a further two per week for seven months while receiving standard radiotherapy and chemotherapy. Tests showed that iron in their tumours reacted with the vitamin to form highly reactive and destructive “free radical” hydrogen peroxide molecules. The free radicals were thought to cause selective DNA damage in cancerous, but not healthy, cells. This in turn was expected to lead to enhanced cancer cell death as well as sensitisation to radiation and chemotherapy drugs. US researcher Dr Garry Buettner, from the University of Iowa, said: “This paper reveals a metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilise existing redox active compounds, like vitamin C, to sensitise cancer cells to radiation and chemotherapy.” The safety study sets the stage for larger Phase II trials investigating whether high-dose vitamin C injections can extend the lifespan of cancer patients.
Note: This study was published in the journal Cancer Cell. For more along these lines, see concise summaries of deeply revealing news articles on promising cancer research.
As a physician, I have encountered many people who believe that heart disease, which is the single biggest cause of death among Americans, is largely controllable. After all, if people ate better, were physically active and stopped smoking, then lots of them would get better. This ignores the fact that people can’t change many risk factors of heart disease like age, race and family genetics. People don’t often seem to feel the same way about cancer. They think it’s out of their control. A ... recent study published in Nature argues that there is a lot we can do. Many studies have shown that environmental risk factors and exposures contribute greatly to many cancers. Diet is related to colorectal cancer. Alcohol and tobacco are related to esophageal cancer. HPV is related to cervical cancer, and hepatitis C is related to liver cancer. And you’d have to be living under a rock not to know that smoking causes lung cancer and that too much sun can lead to skin cancer. Using sophisticated modeling techniques, the researchers argued that less than 30 percent of the lifetime risk of getting many common cancers was because of intrinsic risk factors, or the “bad luck.” The rest were things you can change. [More] recently, in JAMA Oncology, researchers sought to quantify how a healthful lifestyle might actually alter the risk of cancer. They [found that] about 25 percent of cancer in women and 33 percent in men was potentially preventable.
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The phrase “cancer screening saves lives” is ... familiar to most consumers of public service announcements. But that advice may be misleading. The ubiquitous adage ... fails to take into account deaths linked to factors related to the screening itself. For example, prostate cancer screening is known to return “numerous” false positives, writes Vinay Prasad, an assistant professor at Oregon Health and Science University, and contributes to over 1 million prostate biopsies a year. The procedure is “associated with serious harms, including admission to hospital and death.” What’s more, men diagnosed with prostate cancer are “more likely to have a heart attack or commit suicide in the year after diagnosis,” he writes. A similar case can be made for breast cancer screening. Fully 60 percent of women who get regular mammograms for 10 years have been handed a false positive result at some point. Being told you have breast cancer - even if it turns out that the test result was incorrect - has been associated with “psychosocial distress as great as a breast cancer diagnosis.” A massive study of 90,000 women over 25 years found that the regular screening did not change the women’s death rates. In fact, if anything, the screenings harmed some women: Out of every five cancers detected with the technology and treated, one was “not a threat to the woman’s health and did not need treatment such as chemotherapy, surgery or radiation,” all of which can cause serious side effects.
Note: Read more about routine over-diagnosis and unnecessary treatment of cancer in this New York Times article. And learn about the promising cancer research that has been largely suppressed by the medical-industrial complex. For more, see concise summaries of deeply revealing health news articles from reliable major media sources. Then explore the excellent, reliable resources provided in our Health Information Center.
A group of experts advising the nation’s premier cancer research institution has recommended changing the definition of cancer and eliminating the word from some common diagnoses as part of sweeping changes in the nation’s approach to cancer detection and treatment. The recommendations, from a working group of the National Cancer Institute, were published [in] The Journal of the American Medical Association. They say, for instance, that some premalignant conditions, like one that affects the breast called ductal carcinoma in situ, which many doctors agree is not cancer, should be renamed to exclude the word carcinoma so that patients are less frightened and less likely to seek what may be unneeded and potentially harmful treatments that can include the surgical removal of the breast. The group, which includes some of the top scientists in cancer research, also suggested that many lesions detected during breast, prostate, thyroid, lung and other cancer screenings should not be called cancer at all but should instead be reclassified as IDLE conditions, which stands for “indolent lesions of epithelial origin.” The impetus behind the call for change is a growing concern among doctors, scientists and patient advocates that hundreds of thousands of men and women are undergoing needless and sometimes disfiguring and harmful treatments for premalignant and cancerous lesions that are so slow growing they are unlikely to ever cause harm. Once doctors and patients are aware a lesion exists, they typically feel compelled to biopsy, treat and remove it, often at great physical and psychological pain and risk to the patient.
Note: Isn't it interesting that a diagnosis which might not even be accurate can so change a person's life? For more on promising cancer cures which are being suppressed by the medical-industrial complex, see the deeply revealing reports from reliable major media sources available here.
Marijuana, already shown to reduce pain and nausea in cancer patients, may be promising as a cancer-fighting agent against some of the most aggressive forms of the disease. A growing body of early research shows a compound found in marijuana - one that does not produce the plant's psychotropic high - seems to have the ability to "turn off" the activity of a gene responsible for metastasis in breast and other types of cancers. Two scientists at San Francisco's California Pacific Medical Center Research Institute first released data five years ago that showed how this compound - called cannabidiol - reduced the aggressiveness of human breast cancer cells in the lab. "The preclinical trial data is very strong, and there's no toxicity. There's really a lot of research to move ahead with and to get people excited," said Sean McAllister, who along with scientist Pierre Desprez, has been studying the active molecules in marijuana - called cannabinoids - as potent inhibitors of metastatic disease for the past decade. Martin Lee, director of Project CBD, [a] group that works to raise awareness of the scientific promise of the compound, described the cannabidiol research as potent both as a medicine and a myth buster. "It debunks the idea that medicinal marijuana is really about people wanting to get stoned," said Lee, author of Smoke Signals, a book published last month about the medical and social history of marijuana. "Why do they want it when it doesn't even get them high?"
Note: For an educational, 45-minute documentary on this topic titled "What if Cannabis Cured Cancer?," click here. For an informative 15-minute documentary on the health benefits of juicing raw cannabis, click here. For deeply inspiring reports from reliable sources, click here.
Mounting evidence shows ‘cannabinoids’ in marijuana slow cancer growth, inhibit formation of new blood cells that feed a tumor, and help manage pain, fatigue, nausea, and other side effects. Peer-reviewed studies in several countries ... show that THC and other marijuana-derived compounds, known as “cannabinoids,” are effective not only for cancer-symptom management (nausea, pain, loss of appetite, fatigue), they also confer a direct antitumoral effect. A team of Spanish scientists led by Manuel Guzman conducted the first clinical trial assessing the antitumoral action of THC on human beings. THC treatment was associated with significantly reduced tumor cell proliferation in every test subject. Harvard University scientists reported that THC slows tumor growth in common lung cancer and “significantly reduces the ability of the cancer to spread.” What’s more ... THC selectively targets and destroys tumor cells while leaving healthy cells unscathed. Conventional chemotherapy drugs, by contrast, are highly toxic; they indiscriminately damage the brain and body. There is mounting evidence ... that cannabinoids “represent a new class of anticancer drugs that retard cancer growth, inhibit angiogenesis [the formation of new blood cells that feed a tumor] and the metastatic spreading of cancer cells.” Within the medical science community, the discovery that cannabinoids have anti-tumoral properties is increasingly recognized as a seminal advancement in cancer therapeutics.
Note: Yet treatment with cannabinoids continues to be largely illegal in the US. For an informative 15-minute documentary on the health benefits of juicing raw cannabis, click here. For deeply revealing reports from reliable major media sources on promising cancer-cure research, click here.
A single treatment to cure all cancers? Scientists may be one step closer. In a recent study, scientists reported that they successfully tested an antibody treatment that shrank human breast, ovary, colon, bladder, brain, liver and prostate tumors transplanted into mice. The antibody blocks a protein called CD47, which normally sits on the cell surface and issues a “don’t eat me” signal that prevents the body’s immune system from attacking it. About a decade ago, scientists at Stanford University School of Medicine, led by professor of pathology Irving Weissman, discovered that using an antibody to block CD47 cured some cases of leukemia and lymphoma in mice by allowing macrophages to seek and destroy the cancerous cells. In the new study, Weissman’s Stanford team showed that the CD47-blocking antibodies may also work against a number of other cancers. The researchers found that CD47 existed on nearly every cell, which suggests that the protein may be common to all cancers. Cancer cells expressed about three times more CD47 than healthy cells. “If the tumor was highly aggressive, the antibody also blocked metastasis. It’s becoming very clear that, in order for a cancer to survive in the body, it has to find some way to evade the cells of the innate immune system,” said Weissman in a statement. The antibody treatment didn’t work in all cases. Some mice injected with breast cancer cells from a human patient showed no changes after treatment. Yet in five mice with breast cancer, the antibody treatment cured them, with no signs of recurrence four months after treatment.
Note: With millions around the world dying of cancer every year, why aren't the most promising treatments being fast tracked? Why did it take 10 years form Weissman to reach this stage? Why isn't the very promising treatment of DCA, which is both cheap and incredibly promising, being given many millions to move rapidly forward? To read major media articles describing other potential cures not being adequately funded, click here. To understand why some treatments are suppressed, click here.
Born to Chinese immigrants, 17-year-old Angela Zhang of Cupertino, California is a typical American teenager. She's really into shoes and is just learning how to drive. But there is one thing that separates her from every other student at Monta Vista High School, something she first shared with her chemistry teacher, Kavita Gupta. It's a research paper Angela wrote in her spare time -- and it is advanced, to say the least. "Cure for cancer -- a high school student," said Gupta. "It's just so mind-boggling. I just cannot even begin to comprehend how she even thought about it or did this." When she was a freshman, she started reading doctorate level papers on bio-engineering. By sophomore year she'd talked her way into the lab at Stanford, and by junior year was doing her own research. Angela's idea was to mix cancer medicine in a polymer that would attach to nanoparticles -- nanoparticles that would then attach to cancer cells and show up on an MRI, so doctors could see exactly where the tumors are. Then she thought [of aiming] an infrared light at the tumors to melt the polymer and release the medicine, thus killing the cancer cells while leaving healthy cells completely unharmed. It'll take years to know if it works in humans -- but in mice -- the tumors almost completely disappeared. Angela recently entered her project in the national Siemens science contest. It was no contest. She got a check for $100,000.
Note: If this technique has already melted tumors in mice, why is CBS saying it will take years to know if it works in humans? Why wouldn't millions be poured in to fast track research on this exciting technology?
From the island nation known for the quality of its cigars comes some pretty big news today: Cuban medical authorities have released the first therapeutic vaccine for lung cancer. CimaVax-EGF is the result of a 25-year research project at Havana’s Center for Molecular Immunology, and it could make a life or death difference for those facing late-stage lung cancers. CimaVax-EGF isn’t a vaccine in the preventative sense--that is, it doesn’t prevent lung cancer from taking hold in new patients. It’s based on a protein related to uncontrolled cell proliferation--that is, it doesn’t prevent cancer from existing in the first place but attacks the mechanism by which it does harm. As such it can turn aggressive later-stage lung cancer into a manageable chronic disease by creating antibodies that do battle with the proteins that cause uncontrolled cell proliferation, researchers say. Chemotherapy and radiotherapy are still recommended as a primary means of destroying cancerous tissue, but for those showing no improvement the new vaccine could be a literal lifesaver. The vaccine has already been tested in 1,000 patients in Cuba and is being distributed at hospitals there free of charge. That’s a big deal for a country where smoking is part of the national culture and a leading cause of death. If it proves as successful as researchers say it is, it should give those suffering from lung cancer reason to celebrate--just not with a Cohiba.
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An engineered virus, injected into the blood, can selectively target cancer cells throughout the body in what researchers have labelled a medical first. The virus attacked only tumours, leaving the healthy tissue alone, in a small trial on 23 patients, according to the journal Nature. Researchers said the findings could one day "truly transform" therapies. Cancer specialists said using viruses showed "real promise". Using viruses to attack cancers is not a new concept, but they have needed to be injected directly into tumours in order to evade the immune system. The virus, named JX-594 ... was injected at different doses into the blood of 23 patients with cancers which had spread to multiple organs in the body. Prof John Bell, lead researcher and from the University of Ottawa, said: "We are very excited because this is the first time in medical history that a viral therapy has been shown to consistently and selectively replicate in cancer tissue after intravenous infusion in humans. Intravenous delivery is crucial for cancer treatment because it allows us to target tumours throughout the body as opposed to just those that we can directly inject."
Note: With millions of people dying of cancer every year, why isn't this being fast tracked like the AIDS drugs were? For exciting information from reliable sources on promising new cancer cure possibilities, click here.
Doctors have treated only three leukemia patients, but the sensational results from a single shot could be one of the most significant advances in cancer research in decades. Doctors at the University of Pennsylvania say the treatment made the most common type of leukemia completely disappear in two of the patients and reduced it by 70 percent in the third. In each of the patients as much as five pounds of cancerous tissue completely melted away in a few weeks, and a year later it is still gone. The results of the preliminary test “exceeded our wildest expectations,” says immunologist Dr. Carl June a member of the Abramson Cancer Center's research team. Chemotherapy and radiation can hold this form of leukemia at bay for years, but until now the only cure has been a bone marrow transplant. A bone marrow transplant requires a suitable match, works only about half the time, and often brings on severe, life-threatening side effects such as pain and infection. So why has this remarkable treatment been tried so far on only three patients? Both the National Cancer Institute and several pharmaceutical companies declined to pay for the research. Neither applicants nor funders discuss the reasons an application is turned down.
Note: For key reports from reliable sources on hopeful new cancer treatments, click here.
Is the common nature of cancer worldwide purely a man-made phenomenon? That is what some researchers now suggest. Scientists have only found one case of the disease in investigations of hundreds of Egyptian mummies, researcher Rosalie David at the University of Manchester in England said in a statement. The rarity of cancer in mummies suggests it was scarce in antiquity, and "that cancer-causing factors are limited to societies affected by modern industrialization," researcher Michael Zimmerman at Villanova University in Pennsylvania said in a statement. "In an ancient society lacking surgical intervention, evidence of cancer should remain in all cases." Zimmerman was the first to diagnose cancer in an Egyptian mummy by analyzing its tissues on a microscopic level, identifying rectal cancer in an unnamed mummy who had lived in the Dakhleh Oasis during the Ptolemaic period 1,600 to 1,800 years ago. As they analyzed ancient literature, they did not find descriptions of operations for breast and other cancers until the 17th century, and the first reports in the scientific literature of distinctive tumors have only occurred in the past 200 years, such as scrotal cancer in chimney sweepers in 1775, nasal cancer in snuff users in 1761 and Hodgkin's disease in 1832. David and Zimmerman therefore argue that cancer nowadays is largely caused by man-made environmental factors such as pollution and diet. They detailed their findings in the October issue of the journal Nature Reviews Cancer.
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Suzanne Somers is at it again. She's back with a new book [on an] emotional topic: Cancer treatment. Specifically, she argues against what she sees as the vast and often pointless use of chemotherapy. Somers, who has rejected chemo herself, seems to relish the fight. "Cancer's an epidemic," said the 63-year-old actress ... a day before [the] release of Knockout: Interviews with Doctors Who Are Curing Cancer--And How to Prevent Getting It in the First Place, her 19th book. "And yet we keep going back to the same old pot, because it's all we've got. Well, this is a book about options." Though she may be one of the most visible, Somers is hardly the only celebrity who's advocated alternative treatments recently. The late Farrah Fawcett underwent a mix of traditional and alternative treatments, and made a poignant plea for supporting alternative methods in her film, "Farrah's Story." Actress Jenny McCarthy advocates a special dietary regime, supplements, metal detox and delayed vaccines to treat autism. In fact, Somers does view chemotherapy as effective for some cancers, but not for the most common, including lung and breast cancer. Diagnosed with breast cancer a decade ago, she had a lumpectomy and radiation, but declined chemotherapy, as she did more recently when briefly misdiagnosed with pervasive cancer.
Note: To watch a video clip of this, click here. For her harrowing experience of being misdiagnosed with stage four cancer, click here. And if you want to understand how big money sometimes ruthlessly acts to stop cancer cures, click here. For media articles discussing potentially powerful cancer cures and how industry sometimes will not support them, click here.
Spontaneous tumor regressions are among the rarest and most mysterious events in medicine, with only several hundred cases in the literature that can be considered well documented. Regressions have most often been reported in melanoma and in kidney cancer. But the phenomenon may, in fact, be an everyday one, taking place beyond doctors' eyes. A recent study suggests that as many as 1 in 3 breast tumors may vanish on their own before being detected by a doctor. Why do some patients get lucky? Scientists are finding tantalizing evidence that the immune system, the body's defense against disease-causing microbes, kicks in to play a critical role in combating cancer. The evidence includes the fact that some unexplained remissions have occurred after infections, which may propel the immune system into high gear--possibly attacking the cancer tumor as well as the infection. The role of the immune system in controlling cancer has been hotly debated for decades--and indeed many scientists remain unconvinced. But Jedd D. Wolchok, an oncologist at New York's Memorial Sloan-Kettering Cancer Center, thinks there is a connection. A spontaneous remission, he says, is "either divine intervention or the immune system." While few researchers directly study such cases--they are far too rare--they provide hints of what the immune system might be able to do if we could harness it.
Note: The number of these cancer miracles are likely far more than suggested in this article. The problem is that most doctors ignore or consider them insignificant. For a most fascinating example of this, click here. For many exciting reports from major media sources describing potentially promising new cancer treatments, click here.
Cancer researchers have known for years that it was possible in rare cases for some cancers to go away on their own. There were occasional instances of melanomas and kidney cancers that just vanished. And neuroblastoma, a very rare childhood tumor, can go away without treatment. But these were mostly seen as oddities — an unusual pediatric cancer that might not bear on common cancers of adults, a smattering of case reports of spontaneous cures. And since almost every cancer that is detected is treated, it seemed impossible even to ask what would happen if cancers were left alone. Now, though, researchers say they have found a situation in Norway that has let them ask that question about breast cancer. And their new study, to be published Tuesday in The Archives of Internal Medicine, suggests that even invasive cancers may sometimes go away without treatment and in larger numbers than anyone ever believed. Robert M. Kaplan, the chairman of the department of health services at the School of Public Health at the University of California, Los Angeles, [is] persuaded by the analysis. The implications are potentially enormous, Dr. Kaplan said. If the results are replicated, he said, it could eventually be possible for some women to opt for so-called watchful waiting, monitoring a tumor in their breast to see whether it grows. “People have never thought that way about breast cancer,” he added. Dr. Kaplan and his colleague, Dr. Franz Porzsolt, an oncologist at the University of Ulm, said in an editorial that accompanied the study, “If the spontaneous remission hypothesis is credible, it should cause a major re-evaluation in the approach to breast cancer research and treatment.”
Note: For reports from major media sources on many hopeful new developments in the battle against cancer, click here.
There is an epidemic of cancer today. One in three Americans will be diagnosed with cancer, often before the age of 65. Since 1940, we have seen in Western societies a marked and rapid increase in common types of cancer. In fact, cancer in children and adolescents has been rising by 1 to 1.5 percent a year since the 1960's. And these are cancers for which there is no screening. For most common cancers - prostate, breast, colon, lung - rates are much higher in the West than in Asian countries. Yet Asians who emigrate to the United States catch up with the rates of Americans within one or two generations. While in Asia, Asians are protected not by their genes, but by their lifestyle. We continue to invest 97 percent of our cancer research funds in better treatments and early detection. Only 3 percent is invested in tackling causes. The World Cancer Research Fund published a report in 2007 concluding that a majority of cancer cases in Western societies could be avoided with life-style measures: 40 percent from changes in diet and physical activity (more vegetables and fruits, less sugar, less red meat, regular walking or the equivalent activity 30 minutes six times per week), 30 percent from smoking cessation, and about 10 percent from reduced alcohol consumption. We now even have data about how specific foods such as broccoli and cabbages, garlic and onions, green tea or the spice turmeric directly help kill cancer cells and reduce the growth of new blood vessels they need to develop into tumors.
Note: The author of this article, Dr. David Servan-Schreiber, is a clinical professor of psychiatry at the University of Pittsburgh and a founding board member of Doctors Without Borders, USA, and author of Anticancer - A new way of life. For an excellent, inspiring 10-minute video interview with this doctor, click here.
In results that "astounded" scientists, an inexpensive molecule known as DCA was shown to shrink lung, breast and brain tumours in both animal and human tissue experiments. The study was published yesterday in the journal Cancer Cell. "I think DCA can be selective for cancer because it attacks a fundamental process of cancer that is unique to cancer cells," said Dr. Evangelos Michelakis, a professor at the Edmonton university's medical school and one of the study's key authors. The molecule appears to repair damaged mitochondria in cancer cells. "When a cell is getting too old or doesn't function properly, the mitochondria are going to induce the cell death," lead study author Sebastien Bonnet said yesterday. Bonnet says DCA – or dichloroacetate – appears to reverse the mitochondrial changes in a wide range of cancers. "One of the really exciting things about this compound is that it might be able to treat many different forms of cancer because all forms of cancer suppress mitochondrial function," Michelakis said. Bonnet says DCA may also provide an effective cancer treatment because its small size allows easy absorption into the body, ensuring it can reach areas that other drugs cannot, such as brain tumours. Because it's been used to combat other ailments ... DCA has been shown to have few toxic effects on the body. Its previous use means it can be immediately tested on humans. Unlike other cancer drugs, DCA did not appear to have any negative effect on normal cells. It could provide an extremely inexpensive cancer therapy because it's not patented. But ... the lack of a patent could lead to an unwillingness on the part of pharmaceutical companies to fund expensive clinical trials.
Note: Even these scientists realize that though this discovery could be a huge benefit to mankind, because the drug companies will lose profits, they almost certainly will not fund studies. Expensive AIDS drugs with promising results, on the other hand, are rushed through the studies to market. For more reliable, verifiable information on how hugely beneficial health advances are shut down to keep profits high, click here and here.
Doctors have used ultrasound to successfully treat prostate cancer in a new study promising a new alternative to surgery. Prostate is the second most deadly type of cancer in men, with lung cancer the only variant to claim more lives. Treatment is challenging because surgery and radiation can leave men incontinent or impotent. However, a pioneering new technique avoids the risks by using a rod-shaped device inserted into the urethra while guided by magnetic resonance to administer precise bursts of ultrasound. The sound waves heat and destroy the tumour, leaving surrounding areas unharmed. The new study was presented at the annual meeting of the Radiological Society of North America and involved 115 men with localised prostate cancer. After treatment with ultrasound, clinically significant cancer was eliminated in 80 per cent of the group, with 65 per cent having no signs of cancer after one year. Most of the men also saw reduced blood-antigen markers for prostate cancer, and overall no bowel complications were reported. Study co-author Steven Raman, professor of radiology and urology at the University of California at Los Angeles, said: “It’s an outpatient procedure with minimal recovery time. “We saw very good results in the patients, with a dramatic reduction of over 90 per cent in prostate volume and low rates of impotence with almost no incontinence.” The process, called Tulsa-Pro, has been approved for clinical use in Europe.
Note: Why isn't this exciting new development approved or even reported in the US? And learn about a man who developed a similar treatment almost a century ago only to have it quashed by the medical establishment.
Bees may soon be able to take some of the sting out of cancer by detecting it early and getting patients into treatment sooner. Honeybees are known for their exquisitely sensitive sense of smell. They don't have noses, but their feet, tongues and antennae are packed with olfactory glands. They can also be quickly trained to do their "waggle dance" when they associate a specific smell with a food source. Taking advantage of these facts, Portuguese scientist Susana Soares has invented a two-chambered glass dome that uses bees to snuff out cancer. "The glass objects have two enclosures: a smaller chamber that serves as the diagnostic space and a bigger chamber where previously trained bees are kept for the short period of time necessary for them to detect general health," Soares wrote on her website. "People exhale into the smaller chamber, and the bees rush into it if they detect on the breath the odor that they were trained to target." Soares said she could train bees in 10 minutes to identify cancer and other diseases, such as tuberculosis and diabetes in their early stages. By exposing the insects to the odor molecules produced by an illness and then feeding them sugar, they learn to associate the smell with a food reward. Soares said that her bee chamber was an inexpensive, sustainable and highly accurate diagnostic tool. And, she points out, bees, as well as wasps, are already used regularly to sniff out land mines and illegal drugs.
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Dr. Seema Doshi was shocked and terrified when she found a lump in her breast that was eventually confirmed to be cancerous. "That rocked my world," said Dr. Doshi, a dermatologist in private practice. "I thought, â€That's it. I will have to do chemotherapy.'" She was wrong. Dr. Doshi was the beneficiary of a quiet revolution in breast cancer treatment, a slow chipping away at the number of people for whom chemotherapy is recommended. Chemotherapy for decades was considered "the rule, the dogma," for treating breast cancer and other cancers, said Dr. Gabriel Hortobagyi, a breast cancer specialist. But data from a variety of sources offers some confirmation of what many oncologists say anecdotally – the method is on the wane for many cancer patients. Genetic tests can now reveal whether chemotherapy would be beneficial. For many there are better options with an ever-expanding array of drugs, including estrogen blockers and drugs that destroy cancers by attacking specific proteins on the surface of tumors. And there is a growing willingness among oncologists to scale back unhelpful treatments. The result spares thousands each year from the dreaded chemotherapy treatment, with its accompanying hair loss, nausea, fatigue, and potential to cause permanent damage to the heart and to nerves in the hands and feet. The diminution of chemotherapy treatment is happening for some other cancers, too, including lung cancer.
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